TopFIND 4.0

O60832: H/ACA ribonucleoprotein complex subunit DKC1

General Information

Protein names
- H/ACA ribonucleoprotein complex subunit DKC1
- 5.4.99.- {ECO:0000305|PubMed:25219674}
- CBF5 homolog
- Dyskerin
- Nopp140-associated protein of 57 kDa
- Nucleolar protein NAP57
- Nucleolar protein family A member 4
- snoRNP protein DKC1
Gene names DKC1
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID O60832

11

N-termini

5

C-termini

4

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MADAEVIILP KKHKKKKERK SLPEEDVAEI QHAEEFLIKP ESKVAKLDTS QWPLLLKNFD 
        70         80         90        100        110        120 
KLNVRTTHYT PLACGSNPLK REIGDYIRTG FINLDKPSNP SSHEVVAWIR RILRVEKTGH 
       130        140        150        160        170        180 
SGTLDPKVTG CLIVCIERAT RLVKSQQSAG KEYVGIVRLH NAIEGGTQLS RALETLTGAL 
       190        200        210        220        230        240 
FQRPPLIAAV KRQLRVRTIY ESKMIEYDPE RRLGIFWVSC EAGTYIRTLC VHLGLLLGVG 
       250        260        270        280        290        300 
GQMQELRRVR SGVMSEKDHM VTMHDVLDAQ WLYDNHKDES YLRRVVYPLE KLLTSHKRLV 
       310        320        330        340        350        360 
MKDSAVNAIC YGAKIMLPGV LRYEDGIEVN QEIVVITTKG EAICMAIALM TTAVISTCDH 
       370        380        390        400        410        420 
GIVAKIKRVI MERDTYPRKW GLGPKASQKK LMIKQGLLDK HGKPTDSTPA TWKQEYVDYS 
       430        440        450        460        470        480 
ESAKKEVVAE VVKAPQVVAE AAKTAKRKRE SESESDETPP AAPQLIKKEK KKSKKDKKAK 
       490        500        510    
AGLESGAEPG DGDSDTTKKK KKKKKAKEVE LVSE

Isoforms

- Isoform 3 of H/ACA ribonucleoprotein complex subunit 4 - Isoform 3 of H/ACA ribonucleoprotein complex subunit DKC1

Sequence View

        10         20         30         40         50         60 
MADAEVIILP KKHKKKKERK SLPEEDVAEI QHAEEFLIKP ESKVAKLDTS QWPLLLKNFD 
        70         80         90        100        110        120 
KLNVRTTHYT PLACGSNPLK REIGDYIRTG FINLDKPSNP SSHEVVAWIR RILRVEKTGH 
       130        140        150        160        170        180 
SGTLDPKVTG CLIVCIERAT RLVKSQQSAG KEYVGIVRLH NAIEGGTQLS RALETLTGAL 
       190        200        210        220        230        240 
FQRPPLIAAV KRQLRVRTIY ESKMIEYDPE RRLGIFWVSC EAGTYIRTLC VHLGLLLGVG 
       250        260        270        280        290        300 
GQMQELRRVR SGVMSEKDHM VTMHDVLDAQ WLYDNHKDES YLRRVVYPLE KLLTSHKRLV 
       310        320        330        340        350        360 
MKDSAVNAIC YGAKIMLPGV LRYEDGIEVN QEIVVITTKG EAICMAIALM TTAVISTCDH 
       370        380        390        400        410        420 
GIVAKIKRVI MERDTYPRKW GLGPKASQKK LMIKQGLLDK HGKPTDSTPA TWKQEYVDYS 
       430        440        450        460        470        480 
ESAKKEVVAE VVKAPQVVAE AAKTAKRKRE SESESDETPP AAPQLIKKEK KKSKKDKKAK 
       490        500        510    
AGLESGAEPG DGDSDTTKKK KKKKKAKEVE LVSE         10         20         30         40         50         60 
MADAEVIILP KKHKKKKERK SLPEEDVAEI QHAEEFLIKP ESKVAKLDTS QWPLLLKNFD 
        70         80         90        100        110        120 
KLNVRTTHYT PLACGSNPLK REIGDYIRTG FINLDKPSNP SSHEVVAWIR RILRVEKTGH 
       130        140        150        160        170        180 
SGTLDPKVTG CLIVCIERAT RLVKSQQSAG KEYVGIVRLH NAIEGGTQLS RALETLTGAL 
       190        200        210        220        230        240 
FQRPPLIAAV KRQLRVRTIY ESKMIEYDPE RRLGIFWVSC EAGTYIRTLC VHLGLLLGVG 
       250        260        270        280        290        300 
GQMQELRRVR SGVMSEKDHM VTMHDVLDAQ WLYDNHKDES YLRRVVYPLE KLLTSHKRLV 
       310        320        330        340        350        360 
MKDSAVNAIC YGAKIMLPGV LRYEDGIEVN QEIVVITTKG EAICMAIALM TTAVISTCDH 
       370        380        390        400        410        420 
GIVAKIKRVI MERDTYPRKW GLGPKASQKK LMIKQGLLDK HGKPTDSTPA TWKQEYVDYS 
       430        440        450        460        470        480 
ESAKKEVVAE VVKAPQVVAE AAKTAKRKRE SESESDETPP AAPQLIKKEK KKSKKDKKAK 
       490        500        510    
AGLESGAEPG DGDSDTTKKK KKKKKAKEVE LVSE



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Evidence Names:


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Protein Neighborhood

Domains & Features

11 N-termini - 5 C-termini - 4 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)