O15247: Chloride intracellular channel protein 2

General Information

Protein names	- Chloride intracellular channel protein 2 - XAP121
Gene names	CLIC2
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	O15247

2 N-termini

3 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MSGLRPGTQV DPEIELFVKA GSDGESIGNC PFCQRLFMIL WLKGVKFNVT TVDMTRKPEE
        70         80         90        100        110        120
LKDLAPGTNP PFLVYNKELK TDFIKIEEFL EQTLAPPRYP HLSPKYKESF DVGCNLFAKF
       130        140        150        160        170        180
SAYIKNTQKE ANKNFEKSLL KEFKRLDDYL NTPLLDEIDP DSAEEPPVSR RLFLDGDQLT
       190        200        210        220        230        240
LADCSLLPKL NIIKVAAKKY RDFDIPAEFS GVWRYLHNAY AREEFTHTCP EDKEIENTYA

NVAKQKS

Isoforms

Sequence View

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(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

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Protein Neighborhood

Domains & Features

2 N-termini - 3 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
O15247-1-unknown	MSGLRP...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
O15247-162-unknown	SAEEPP...	162		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC10708

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...EIDPDS	161	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10708
...RLFLDG	175	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000470577
...RLFLDG	175	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000318558
...AKQKS	247	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAB_HUMAN	161	DPDS.\|.SAEE	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Complementary positional proteo... (M14.017)	20526345,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)