Q6NZY4: Zinc finger CCHC domain-containing protein 8
Protein names | - Zinc finger CCHC domain-containing protein 8 - TRAMP-like complex RNA-binding factor ZCCHC8 |
---|---|
Gene names | ZCCHC8 |
Organism | Homo sapiens |
Protease Family | |
Protease ID | |
Chromosome location | |
UniProt ID | Q6NZY4 |
8
N-termini
2
C-termini
1
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MAAEVYFGDL ELFEPFDHPE ESIPKPVHTR FKDDDGDEED ENGVGDAELR ERLRQCEETI
70 80 90 100 110 120
EQLRAENQEL KRKLNILTRP SGILVNDTKL DGPILQILFM NNAISKQYHQ EIEEFVSNLV
130 140 150 160 170 180
KRFEEQQKND VEKTSFNLLP QPSSIVLEED HKVEESCAIK NNKEAFSVVG SVLYFTNFCL
190 200 210 220 230 240
DKLGQPLLNE NPQLSEGWEI PKYHQVFSHI VSLEGQEIQV KAKRPKPHCF NCGSEEHQMK
250 260 270 280 290 300
DCPMPRNAAR ISEKRKEYMD ACGEANNQNF QQRYHAEEVE ERFGRFKPGV ISEELQDALG
310 320 330 340 350 360
VTDKSLPPFI YRMRQLGYPP GWLKEAELEN SGLALYDGKD GTDGETEVGE IQQNKSVTYD
370 380 390 400 410 420
LSKLVNYPGF NISTPRGIPD EWRIFGSIPM QACQQKDVFA NYLTSNFQAP GVKSGNKRSS
430 440 450 460 470 480
SHSSPGSPKK QKNESNSAGS PADMELDSDM EVPHGSQSSE SFQFQPPLPP DTPPLPRGTP
490 500 510 520 530 540
PPVFTPPLPK GTPPLTPSDS PQTRTASGAV DEDALTLEEL EEQQRRIWAA LEQAESVNSD
550 560 570 580 590 600
SDVPVDTPLT GNSVASSPCP NELDLPVPEG KTSEKQTLDE PEVPEIFTKK SEAGHASSPD
610 620 630 640 650 660
SEVTSLCQKE KAELAPVNTE GALLDNGSVV PNCDISNGGS QKLFPADTSP STATKIHSPI
670 680 690 700
PDMSKFATGI TPFEFENMAE STGMYLRIRS LLKNSPRNQQ KNKKASE
Isoforms
- Isoform 2 of Zinc finger CCHC domain-containing protein 8Sequence View
10 20 30 40 50 60
MAAEVYFGDL ELFEPFDHPE ESIPKPVHTR FKDDDGDEED ENGVGDAELR ERLRQCEETI
70 80 90 100 110 120
EQLRAENQEL KRKLNILTRP SGILVNDTKL DGPILQILFM NNAISKQYHQ EIEEFVSNLV
130 140 150 160 170 180
KRFEEQQKND VEKTSFNLLP QPSSIVLEED HKVEESCAIK NNKEAFSVVG SVLYFTNFCL
190 200 210 220 230 240
DKLGQPLLNE NPQLSEGWEI PKYHQVFSHI VSLEGQEIQV KAKRPKPHCF NCGSEEHQMK
250 260 270 280 290 300
DCPMPRNAAR ISEKRKEYMD ACGEANNQNF QQRYHAEEVE ERFGRFKPGV ISEELQDALG
310 320 330 340 350 360
VTDKSLPPFI YRMRQLGYPP GWLKEAELEN SGLALYDGKD GTDGETEVGE IQQNKSVTYD
370 380 390 400 410 420
LSKLVNYPGF NISTPRGIPD EWRIFGSIPM QACQQKDVFA NYLTSNFQAP GVKSGNKRSS
430 440 450 460 470 480
SHSSPGSPKK QKNESNSAGS PADMELDSDM EVPHGSQSSE SFQFQPPLPP DTPPLPRGTP
490 500 510 520 530 540
PPVFTPPLPK GTPPLTPSDS PQTRTASGAV DEDALTLEEL EEQQRRIWAA LEQAESVNSD
550 560 570 580 590 600
SDVPVDTPLT GNSVASSPCP NELDLPVPEG KTSEKQTLDE PEVPEIFTKK SEAGHASSPD
610 620 630 640 650 660
SEVTSLCQKE KAELAPVNTE GALLDNGSVV PNCDISNGGS QKLFPADTSP STATKIHSPI
670 680 690 700
PDMSKFATGI TPFEFENMAE STGMYLRIRS LLKNSPRNQQ KNKKASE
Protein Neighborhood
Domains & Features
8 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
Q6NZY4-2-unknown | MAAEVY... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
Q6NZY4-2-Acetylation | AAEVYF... | 2 | acetylation- | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | ||
Q6NZY4-239-unknown | MKDCPM... | 239 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt95040 | |||
Q6NZY4-344- | GETEVG... | 344 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
Q6NZY4-344- | GETEVG... | 344 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1SDBJurkat_Mix | 23264352 | |||
Q6NZY4-344-unknown | GETEVG... | 344 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt171622 | |||
Q6NZY4-505- | TASGAV... | 505 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
Q6NZY4-505- | TASGAV... | 505 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1SDBJurkat_Mix | 23264352 | |||
Q6NZY4-505-unknown | TASGAV... | 505 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt173827 | |||
Q6NZY4-514-unknown | ALTLEE... | 514 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC12589 | |||
Q6NZY4-514-unknown | ALTLEE... | 514 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt149244 |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...AVDEDA | 513 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC12589 | |||
...AVDEDA | 513 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt132629 | |||
...KKASE | 707 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
...KKASE | 707 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt90658 | |||
...KKASE | 707 | COFRADIC | Gevaert K. | Van Damme P et al.: Complementary positional proteomics for screening substrates... | 20526345, | |||
...KKASE | 707 | COFRADIC | Gevaert K. | Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates... | 20526345, |
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
GRAB_HUMAN | 513 | DEDA.|.ALTL | inferred from experiment | unknown | MEROPS | Gevaert K | Van Damme P et al.:Analysis of protein processing ... (S01.010) | 18836177, |
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
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