Q9NQ55: Suppressor of SWI4 1 homolog

General Information

Protein names	- Suppressor of SWI4 1 homolog - Ssf-1 - Brix domain-containing protein 3 - Peter Pan homolog
Gene names	PPAN
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9NQ55

9 N-termini

5 C-termini

4 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Suppressor of SWI4 1 homolog - Isoform 3 of Suppressor of SWI4 1 homolog

Sequence View

        10         20         30         40         50         60
MGQSGRSRHQ KRARAQAQLR NLEAYAANPH SFVFTRGCTG RNIRQLSLDV RRVMEPLTAS
        70         80         90        100        110        120
RLQVRKKNSL KDCVAVAGPL GVTHFLILSK TETNVYFKLM RLPGGPTLTF QVKKYSLVRD
       130        140        150        160        170        180
VVSSLRRHRM HEQQFAHPPL LVLNSFGPHG MHVKLMATMF QNLFPSINVH KVNLNTIKRC
       190        200        210        220        230        240
LLIDYNPDSQ ELDFRHYSIK VVPVGASRGM KKLLQEKFPN MSRLQDISEL LATGAGLSES
       250        260        270        280        290        300
EAEPDGDHNI TELPQAVAGR GNMRAQQSAV RLTEIGPRMT LQLIKVQEGV GEGKVMFHSF
       310        320        330        340        350        360
VSKTEEELQA ILEAKEKKLR LKAQRQAQQA QNVQRKQEQR EAHRKKSLEG MKKARVGGSD
       370        380        390        400        410        420
EEASGIPSRT ASLELGEDDD EQEDDDIEYF CQAVGEAPSE DLFPEAKQKR LAKSPGRKRK
       430        440        450        460        470
RWEMDRGRGR LCDQKFPKTK DKSQGAQARR GPRGASRDGG RGRGRGRPGK RVA         10         20         30         40         50         60
MGQSGRSRHQ KRARAQAQLR NLEAYAANPH SFVFTRGCTG RNIRQLSLDV RRVMEPLTAS
        70         80         90        100        110        120
RLQVRKKNSL KDCVAVAGPL GVTHFLILSK TETNVYFKLM RLPGGPTLTF QVKKYSLVRD
       130        140        150        160        170        180
VVSSLRRHRM HEQQFAHPPL LVLNSFGPHG MHVKLMATMF QNLFPSINVH KVNLNTIKRC
       190        200        210        220        230        240
LLIDYNPDSQ ELDFRHYSIK VVPVGASRGM KKLLQEKFPN MSRLQDISEL LATGAGLSES
       250        260        270        280        290        300
EAEPDGDHNI TELPQAVAGR GNMRAQQSAV RLTEIGPRMT LQLIKVQEGV GEGKVMFHSF
       310        320        330        340        350        360
VSKTEEELQA ILEAKEKKLR LKAQRQAQQA QNVQRKQEQR EAHRKKSLEG MKKARVGGSD
       370        380        390        400        410        420
EEASGIPSRT ASLELGEDDD EQEDDDIEYF CQAVGEAPSE DLFPEAKQKR LAKSPGRKRK
       430        440        450        460        470
RWEMDRGRGR LCDQKFPKTK DKSQGAQARR GPRGASRDGG RGRGRGRPGK RVA

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

9 N-termini - 5 C-termini - 4 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q9NQ55-1-unknown	MGQSGR...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9NQ55-1-unknown	MGQSGR...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt90759
Q9NQ55-1-unknown	MGQSGR...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt90760
Q9NQ55-221-unknown	MSRLQD...	221	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC15010
Q9NQ55-221-unknown	MSRLQD...	221	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt147394
Q9NQ55-221-unknown	MSRLQD...	221	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt147395
Q9NQ55-231-unknown	LATGAG...	231	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC15013
Q9NQ55-231-unknown	LATGAG...	231	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt147775
Q9NQ55-231-unknown	LATGAG...	231	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt147776
Q9NQ55-232-unknown	ATGAGL...	232	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC15016
Q9NQ55-232-unknown	ATGAGL...	232	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt147814
Q9NQ55-232-unknown	ATGAGL...	232	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt147815
Q9NQ55-246-unknown	GDHNIT...	246	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt168380
Q9NQ55-246-unknown	GDHNIT...	246	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt168381
Q9NQ55-246-	GDHNIT...	246		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
Q9NQ55-246-	GDHNIT...	246		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q9NQ55-246-	GDHNIT...	246		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q9NQ55-246-	GDHNIT...	246		Subtiligase Based Positive Selection		Wells	apoptotic_RPMI_Dox	23264352
Q9NQ55-246-	GDHNIT...	246		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
Q9NQ55-393-unknown	AVGEAP...	393	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt171001
Q9NQ55-393-unknown	AVGEAP...	393	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt171002
Q9NQ55-393-	AVGEAP...	393		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q9NQ55-393-	AVGEAP...	393		Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
Q9NQ55-402-unknown	LFPEAK...	402	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC13377
Q9NQ55-402-unknown	LFPEAK...	402	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt152024
Q9NQ55-402-unknown	LFPEAK...	402	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt152025

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...EKFPNM	220	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC15010
...EKFPNM	220	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt130741
...EKFPNM	220	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt130742
...DISELL	230	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC15013
...DISELL	230	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt131131
...DISELL	230	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt131132
...ISELLA	231	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC15016
...ISELLA	231	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt131169
...ISELLA	231	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt131170
...APSEDL	401	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC13377
...APSEDL	401	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt135434
...APSEDL	401	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt135435
...GKRVA	473	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAM_HUMAN	220	FPNM.\|.MSRL	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,
GRAM_HUMAN	230	SELL.\|.LATG	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,
GRAM_HUMAN	231	ELLA.\|.ATGA	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,
GRAB_HUMAN	401	SEDL.\|.LFPE	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Complementary positional proteo... (M14.017)	20526345,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)