Q9Y450: HBS1-like protein
Protein names | - HBS1-like protein - ERFS |
---|---|
Gene names | HBS1L |
Organism | Homo sapiens |
Protease Family | |
Protease ID | |
Chromosome location | |
UniProt ID | Q9Y450 |
8
N-termini
3
C-termini
2
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MARHRNVRGY NYDEDFEDDD LYGQSVEDDY CISPSTAAQF IYSRRDKPSV EPVEEYDYED
70 80 90 100 110 120
LKESSNSVSN HQLSGFDQAR LYSCLDHMRE VLGDAVPDEI LIEAVLKNKF DVQKALSGVL
130 140 150 160 170 180
EQDRVQSLKD KNEATVSTGK IAKGKPVDSQ TSRSESEIVP KVAKMTVSGK KQTMGFEVPG
190 200 210 220 230 240
VSSEENGHSF HTPQKGPPIE DAIASSDVLE TASKSANPPH TIQASEEQSS TPAPVKKSGK
250 260 270 280 290 300
LRQQIDVKAE LEKRQGGKQL LNLVVIGHVD AGKSTLMGHM LYLLGNINKR TMHKYEQESK
310 320 330 340 350 360
KAGKASFAYA WVLDETGEER ERGVTMDVGM TKFETTTKVI TLMDAPGHKD FIPNMITGAA
370 380 390 400 410 420
QADVAVLVVD ASRGEFEAGF ETGGQTREHG LLVRSLGVTQ LAVAVNKMDQ VNWQQERFQE
430 440 450 460 470 480
ITGKLGHFLK QAGFKESDVG FIPTSGLSGE NLITRSQSSE LTKWYKGLCL LEQIDSFKPP
490 500 510 520 530 540
QRSIDKPFRL CVSDVFKDQG SGFCITGKIE AGYIQTGDRL LAMPPNETCT VKGITLHDEP
550 560 570 580 590 600
VDWAAAGDHV SLTLVGMDII KINVGCIFCG PKVPIKACTR FRARILIFNI EIPITKGFPV
610 620 630 640 650 660
LLHYQTVSEP AVIKRLISVL NKSTGEVTKK KPKFLTKGQN ALVELQTQRP IALELYKDFK
670 680
ELGRFMLRYG GSTIAAGVVT EIKE
Isoforms
- Isoform 2 of HBS1-like protein - Isoform 3 of HBS1-like proteinSequence View
10 20 30 40 50 60
MARHRNVRGY NYDEDFEDDD LYGQSVEDDY CISPSTAAQF IYSRRDKPSV EPVEEYDYED
70 80 90 100 110 120
LKESSNSVSN HQLSGFDQAR LYSCLDHMRE VLGDAVPDEI LIEAVLKNKF DVQKALSGVL
130 140 150 160 170 180
EQDRVQSLKD KNEATVSTGK IAKGKPVDSQ TSRSESEIVP KVAKMTVSGK KQTMGFEVPG
190 200 210 220 230 240
VSSEENGHSF HTPQKGPPIE DAIASSDVLE TASKSANPPH TIQASEEQSS TPAPVKKSGK
250 260 270 280 290 300
LRQQIDVKAE LEKRQGGKQL LNLVVIGHVD AGKSTLMGHM LYLLGNINKR TMHKYEQESK
310 320 330 340 350 360
KAGKASFAYA WVLDETGEER ERGVTMDVGM TKFETTTKVI TLMDAPGHKD FIPNMITGAA
370 380 390 400 410 420
QADVAVLVVD ASRGEFEAGF ETGGQTREHG LLVRSLGVTQ LAVAVNKMDQ VNWQQERFQE
430 440 450 460 470 480
ITGKLGHFLK QAGFKESDVG FIPTSGLSGE NLITRSQSSE LTKWYKGLCL LEQIDSFKPP
490 500 510 520 530 540
QRSIDKPFRL CVSDVFKDQG SGFCITGKIE AGYIQTGDRL LAMPPNETCT VKGITLHDEP
550 560 570 580 590 600
VDWAAAGDHV SLTLVGMDII KINVGCIFCG PKVPIKACTR FRARILIFNI EIPITKGFPV
610 620 630 640 650 660
LLHYQTVSEP AVIKRLISVL NKSTGEVTKK KPKFLTKGQN ALVELQTQRP IALELYKDFK
670 680
ELGRFMLRYG GSTIAAGVVT EIKE
10 20 30 40 50 60
MARHRNVRGY NYDEDFEDDD LYGQSVEDDY CISPSTAAQF IYSRRDKPSV EPVEEYDYED
70 80 90 100 110 120
LKESSNSVSN HQLSGFDQAR LYSCLDHMRE VLGDAVPDEI LIEAVLKNKF DVQKALSGVL
130 140 150 160 170 180
EQDRVQSLKD KNEATVSTGK IAKGKPVDSQ TSRSESEIVP KVAKMTVSGK KQTMGFEVPG
190 200 210 220 230 240
VSSEENGHSF HTPQKGPPIE DAIASSDVLE TASKSANPPH TIQASEEQSS TPAPVKKSGK
250 260 270 280 290 300
LRQQIDVKAE LEKRQGGKQL LNLVVIGHVD AGKSTLMGHM LYLLGNINKR TMHKYEQESK
310 320 330 340 350 360
KAGKASFAYA WVLDETGEER ERGVTMDVGM TKFETTTKVI TLMDAPGHKD FIPNMITGAA
370 380 390 400 410 420
QADVAVLVVD ASRGEFEAGF ETGGQTREHG LLVRSLGVTQ LAVAVNKMDQ VNWQQERFQE
430 440 450 460 470 480
ITGKLGHFLK QAGFKESDVG FIPTSGLSGE NLITRSQSSE LTKWYKGLCL LEQIDSFKPP
490 500 510 520 530 540
QRSIDKPFRL CVSDVFKDQG SGFCITGKIE AGYIQTGDRL LAMPPNETCT VKGITLHDEP
550 560 570 580 590 600
VDWAAAGDHV SLTLVGMDII KINVGCIFCG PKVPIKACTR FRARILIFNI EIPITKGFPV
610 620 630 640 650 660
LLHYQTVSEP AVIKRLISVL NKSTGEVTKK KPKFLTKGQN ALVELQTQRP IALELYKDFK
670 680
ELGRFMLRYG GSTIAAGVVT EIKE
Protein Neighborhood
Domains & Features
8 N-termini - 3 C-termini - 2 Cleavages - 0 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
Q9Y450-1-unknown | MARHRN... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
Q9Y450-1-unknown | MARHRN... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt76775 | |||
Q9Y450-1-unknown | MARHRN... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt76776 | |||
Q9Y450-36-unknown | TAAQFI... | 36 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC15171 | |||
Q9Y450-36-unknown | TAAQFI... | 36 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC13638 | |||
Q9Y450-36-unknown | TAAQFI... | 36 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt138012 | |||
Q9Y450-49-unknown | SVEPVE... | 49 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt175974 | |||
Q9Y450-49- | SVEPVE... | 49 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1s_bort | 23264352 | |||
Q9Y450-67-unknown | SVSNHQ... | 67 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt176588 | |||
Q9Y450-67- | SVSNHQ... | 67 | Subtiligase Based Positive Selection | Wells | MM1SDBJurkat_Untreated | 23264352 | |||
Q9Y450-215-unknown | SANPPH... | 215 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt168191 | |||
Q9Y450-215- | SANPPH... | 215 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_bortezomib | 23264352 | |||
Q9Y450-215- | SANPPH... | 215 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1SDBJurkat_Mix | 23264352 | |||
Q9Y450-215- | SANPPH... | 215 | Subtiligase Based Positive Selection | Wells | apoptosis_U266_bortezomib_induced | 23264352 |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...CISPST | 35 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC15171 | |||
...CISPST | 35 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC13638 | |||
...CISPST | 35 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt121026 | |||
...CISPST | 35 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt153778 | |||
...TEIKE | 684 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
...TEIKE | 684 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt72394 | |||
...TEIKE | 684 | COFRADIC | Gevaert K. | Van Damme P et al.: Complementary positional proteomics for screening substrates... | 20526345, | |||
...TEIKE | 684 | COFRADIC | Gevaert K. | Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates... | 20526345, | |||
...TEIKE | 684 | COFRADIC | Gevaert K. | Van Damme P et al.: Complementary positional proteomics for screening substrates... | 20526345, | |||
...TEIKE | 684 | COFRADIC | Gevaert K. | Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates... | 20526345, |
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
GRAM_HUMAN | 35 | SPST.|.TAAQ | inferred from experiment | unknown | MEROPS | Bovenschen N | de Poot SA et al.:Human and mouse granzyme M disp... (S01.139) | 21564021, |
GRAB_HUMAN | 35 | SPST.|.TAAQ | inferred from experiment | unknown | MEROPS | Gevaert K | Van Damme P et al.:Complementary positional proteo... (M14.017) | 20526345, |
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|