O60499: Syntaxin-10

General Information

Protein names	- Syntaxin-10 - Syn10
Gene names	STX10
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	O60499

6 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MSLEDPFFVV RGEVQKAVNT ARGLYQRWCE LLQESAAVGR EELDWTTNEL RNGLRSIEWD
        70         80         90        100        110        120
LEDLEETIGI VEANPGKFKL PAGDLQERKV FVERMREAVQ EMKDHMVSPT AVAFLERNNR
       130        140        150        160        170        180
EILAGKPAAQ KSPSDLLDAS AVSATSRYIE EQQATQQLIM DEQDQQLEMV SGSIQVLKHM
       190        200        210        220        230        240
SGRVGEELDE QGIMLDAFAQ EMDHTQSRMD GVLRKLAKVS HMTSDRRQWC AIAVLVGVLL

LVLILLFSL

Isoforms

- Isoform 2 of Syntaxin-10

Sequence View

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Protein Neighborhood

Domains & Features

6 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
O60499-1-unknown	MSLEDP...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt90991
O60499-2-unknown	MSLEDP...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
O60499-2-Acetylation	SLEDPF...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
O60499-2-Acetylation	SLEDPF...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
O60499-2-Acetylation	SLEDPF...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
O60499-2-Acetylation	SLEDPF...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt111162
O60499-139-	ASAVSA...	139			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_Etoposide	23264352
O60499-139-unknown	ASAVSA...	139			unknown			Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
O60499-139-unknown	ASAVSA...	139		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt162171
O60499-197-unknown	AFAQEM...	197		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC10823
O60499-197-unknown	AFAQEM...	197			unknown			Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
O60499-197-unknown	AFAQEM...	197		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt144631

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...GIMLDA	196	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10823
...GIMLDA	196	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt127898
...LLFSL	249	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...LLFSL	249	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt86609

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAB_HUMAN	196	MLDA.\|.AFAQ	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Analysis of protein processing ... (S01.010)	18836177,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)