P63151: Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform

General Information

Protein names	- Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform - PP2A subunit B isoform B55-alpha - PP2A subunit B isoform PR55-alpha - PP2A subunit B isoform R2-alpha - PP2A subunit B isoform alpha
Gene names	PPP2R2A
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P63151

3 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAGAGGGNDI QWCFSQVKGA VDDDVAEADI ISTVEFNHSG ELLATGDKGG RVVIFQQEQE
        70         80         90        100        110        120
NKIQSHSRGE YNVYSTFQSH EPEFDYLKSL EIEEKINKIR WLPQKNAAQF LLSTNDKTIK
       130        140        150        160        170        180
LWKISERDKR PEGYNLKEED GRYRDPTTVT TLRVPVFRPM DLMVEASPRR IFANAHTYHI
       190        200        210        220        230        240
NSISINSDYE TYLSADDLRI NLWHLEITDR SFNIVDIKPA NMEELTEVIT AAEFHPNSCN
       250        260        270        280        290        300
TFVYSSSKGT IRLCDMRASA LCDRHSKLFE EPEDPSNRSF FSEIISSISD VKFSHSGRYM
       310        320        330        340        350        360
MTRDYLSVKI WDLNMENRPV ETYQVHEYLR SKLCSLYEND CIFDKFECCW NGSDSVVMTG
       370        380        390        400        410        420
SYNNFFRMFD RNTKRDITLE ASRENNKPRT VLKPRKVCAS GKRKKDEISV DSLDFNKKIL
       430        440
HTAWHPKENI IAVATTNNLY IFQDKVN

Isoforms

- Isoform 2 of Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform

Sequence View

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Protein Neighborhood

Domains & Features

3 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name
P63151-2-unknown	MAGAGG...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P63151-2-Acetylation	AGAGGG...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P63151-2-Acetylation	AGAGGG...	2	acetylation-		other		CNRS/ISV	Large_scale_NTA_Human
P63151-412-unknown	SLDFNK...	412		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC11787
P63151-412-unknown	SLDFNK...	412		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt152359

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...EISVDS	411	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC11787
...EISVDS	411	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt135770
...QDKVN	447	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...QDKVN	447	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt61366

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAB_HUMAN	411	SVDS.\|.SLDF	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Analysis of protein processing ... (S01.010)	18836177,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)