Q9NUQ8: ATP-binding cassette sub-family F member 3

General Information

Protein names	- ATP-binding cassette sub-family F member 3
Gene names	ABCF3
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9NUQ8

5 N-termini

3 C-termini

2 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MATCAEILRS EFPEIDGQVF DYVTGVLHSG SADFESVDDL VEAVGELLQE VSGDSKDDAG
        70         80         90        100        110        120
IRAVCQRMYN TLRLAEPQSQ GNSQVLLDAP IQLSKITENY DCGTKLPGLL KREQSSTVNA
       130        140        150        160        170        180
KKLEKAEARL KAKQEKRSEK DTLKTSNPLV LEEASASQAG SRKESRLESS GKNKSYDVRI
       190        200        210        220        230        240
ENFDVSFGDR VLLAGADVNL AWGRRYGLVG RNGLGKTTLL KMLATRSLRV PAHISLLHVE
       250        260        270        280        290        300
QEVAGDDTPA LQSVLESDSV REDLLRRERE LTAQIAAGRA EGSEAAELAE IYAKLEEIEA
       310        320        330        340        350        360
DKAPARASVI LAGLGFTPKM QQQPTREFSG GWRMRLALAR ALFARPDLLL LDEPTNMLDV
       370        380        390        400        410        420
RAILWLENYL QTWPSTILVV SHDRNFLNAI ATDIIHLHSQ RLDGYRGDFE TFIKSKQERL
       430        440        450        460        470        480
LNQQREYEAQ QQYRQHIQVF IDRFRYNANR ASQVQSKLKM LEKLPELKPV DKESEVVMKF
       490        500        510        520        530        540
PDGFEKFSPP ILQLDEVDFY YDPKHVIFSR LSVSADLESR ICVVGENGAG KSTMLKLLLG
       550        560        570        580        590        600
DLAPVRGIRH AHRNLKIGYF SQHHVEQLDL NVSAVELLAR KFPGRPEEEY RHQLGRYGIS
       610        620        630        640        650        660
GELAMRPLAS LSGGQKSRVA FAQMTMPCPN FYILDEPTNH LDMETIEALG RALNNFRGGV
       670        680        690        700
ILVSHDERFI RLVCRELWVC EGGGVTRVEG GFDQYRALLQ EQFRREGFL

Isoforms

- Isoform 2 of ATP-binding cassette sub-family F member 3

Sequence View

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Protein Neighborhood

Domains & Features

5 N-termini - 3 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q9NUQ8-2-unknown	MATCAE...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9NUQ8-1-unknown	MATCAE...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt65990
Q9NUQ8-2-Acetylation	ATCAEI...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9NUQ8-2-Acetylation	ATCAEI...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
Q9NUQ8-2-Acetylation	ATCAEI...	2	acetylation-		other		CNRS/ISV	Large_scale_NTA_Human
Q9NUQ8-2-Acetylation	ATCAEI...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
Q9NUQ8-2-Acetylation	ATCAEI...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt110086
Q9NUQ8-55-unknown	SKDDAG...	55		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC13415
Q9NUQ8-144-unknown	KTSNPL...	144		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC15051
Q9NUQ8-144-unknown	KTSNPL...	144		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt144226

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...EVSGDS	54	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC13415
...EVSGDS	54	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt122619
...EKDTLK	143	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC15051
...EKDTLK	143	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt127479
...REGFL	709	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...REGFL	709	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt61608

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAB_HUMAN	54	SGDS.\|.SKDD	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Complementary positional proteo... (M14.017)	20526345,
GRAM_HUMAN	143	DTLK.\|.KTSN	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)