P46976: Glycogenin-1

General Information

Protein names	- Glycogenin-1 - GN-1 - GN1 - 2.4.1.186 {ECO:0000269\|PubMed:22160680, ECO:0000269\|PubMed:30356213}
Gene names	GYG1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P46976

4 N-termini

3 C-termini

1 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform GN-1 of Glycogenin-1 - Isoform GN-1S of Glycogenin-1

Sequence View

        10         20         30         40         50         60
MTDQAFVTLT TNDAYAKGAL VLGSSLKQHR TTRRLVVLAT PQVSDSMRKV LETVFDEVIM
        70         80         90        100        110        120
VDVLDSGDSA HLTLMKRPEL GVTLTKLHCW SLTQYSKCVF MDADTLVLAN IDDLFDREEL
       130        140        150        160        170        180
SAAPDPGWPD CFNSGVFVYQ PSVETYNQLL HLASEQGSFD GGDQGILNTF FSSWATTDIR
       190        200        210        220        230        240
KHLPFIYNLS SISIYSYLPA FKVFGASAKV VHFLGRVKPW NYTYDPKTKS VKSEAHDPNM
       250        260        270        280        290        300
THPEFLILWW NIFTTNVLPL LQQFGLVKDT CSYVNVLSDL VYTLAFSCGF CRKEDVSGAI
       310        320        330        340        350
SHLSLGEIPA MAQPFVSSEE RKERWEQGQA DYMGADSFDN IKRKLDTYLQ         10         20         30         40         50         60
MTDQAFVTLT TNDAYAKGAL VLGSSLKQHR TTRRLVVLAT PQVSDSMRKV LETVFDEVIM
        70         80         90        100        110        120
VDVLDSGDSA HLTLMKRPEL GVTLTKLHCW SLTQYSKCVF MDADTLVLAN IDDLFDREEL
       130        140        150        160        170        180
SAAPDPGWPD CFNSGVFVYQ PSVETYNQLL HLASEQGSFD GGDQGILNTF FSSWATTDIR
       190        200        210        220        230        240
KHLPFIYNLS SISIYSYLPA FKVFGASAKV VHFLGRVKPW NYTYDPKTKS VKSEAHDPNM
       250        260        270        280        290        300
THPEFLILWW NIFTTNVLPL LQQFGLVKDT CSYVNVLSDL VYTLAFSCGF CRKEDVSGAI
       310        320        330        340        350
SHLSLGEIPA MAQPFVSSEE RKERWEQGQA DYMGADSFDN IKRKLDTYLQ

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

4 N-termini - 3 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name
P46976-1-unknown	MTDQAF...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt76118
P46976-1-unknown	MTDQAF...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt76119
P46976-2-unknown	MTDQAF...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P46976-2-Acetylation	TDQAFV...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P46976-2-Acetylation	TDQAFV...	2	acetylation-		other		CNRS/ISV	Large_scale_NTA_Human
P46976-2-Acetylation	TDQAFV...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt111616
P46976-2-Acetylation	TDQAFV...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt111615
P46976-337-unknown	SFDNIK...	337		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC11547
P46976-337-unknown	SFDNIK...	337		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt150326

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
...YMGADS	336	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC11547
...YMGADS	336	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt133721
...DTYLQ	350	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
...DTYLQ	350	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt71736
...DTYLQ	350		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...DTYLQ	350		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAB_HUMAN	336	GADS.\|.SFDN	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Analysis of protein processing ... (S01.010)	18836177,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)