O43903: Growth arrest-specific protein 2

General Information

Protein names	- Growth arrest-specific protein 2 - GAS-2
Gene names	GAS2
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	O43903

3 N-termini

7 C-termini

2 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MCTALSPKVR SGPGLSDMHQ YSQWLASRHE ANLLPMKEDL ALWLTNLLGK EITAETFMEK
        70         80         90        100        110        120
LDNGALLCQL AETMQEKFKE SMDANKPTKN LPLKKIPCKT SAPSGSFFAR DNTANFLSWC
       130        140        150        160        170        180
RDLGVDETCL FESEGLVLHK QPREVCLCLL ELGRIAARYG VEPPGLIKLE KEIEQEETLS
       190        200        210        220        230        240
APSPSPSPSS KSSGKKSTGN LLDDAVKRIS EDPPCKCPNK FCVERLSQGR YRVGEKILFI
       250        260        270        280        290        300
RMLHNKHVMV RVGGGWETFA GYLLKHDPCR MLQISRVDGK TSPIQSKSPT LKDMNPDNYL
       310
VVSASYKAKK EIK

Isoforms

- Isoform 2 of Growth arrest-specific protein 2

Sequence View

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Protein Neighborhood

Domains & Features

3 N-termini - 7 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
O43903-1-unknown	MCTALS...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
O43903-279-unknown	GKTSPI...	279	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC1437
O43903-298-unknown	NYLVVS...	298	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10805

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...ESEGLV	136	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000434478
...ELGRIA	155	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000433182
...ETLSAP	181	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000432584
...LLDDAV	205	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000435946
...ISRVDG	278	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC1437
...DMNPDN	297	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10805
...KKEIK	313	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CASP3_HUMAN	278	RVDG.\|.GKTS	inferred from experiment	unknown	MEROPS	Brancolini C	Sgorbissa A et al.:Caspase-3 and caspase-7 but not... (C14.003)	10564664,
GRAB_HUMAN	297	NPDN.\|.NYLV	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Analysis of protein processing ... (S01.010)	18836177,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)