Q96BK5: PIN2/TERF1-interacting telomerase inhibitor 1

General Information

Protein names	- PIN2/TERF1-interacting telomerase inhibitor 1 - Liver-related putative tumor suppressor - Pin2-interacting protein X1 - Protein 67-11-3 - TRF1-interacting protein 1
Gene names	PINX1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q96BK5

3 N-termini

3 C-termini

2 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MSMLAERRRK QKWAVDPQNT AWSNDDSKFG QRMLEKMGWS KGKGLGAQEQ GATDHIKVQV
        70         80         90        100        110        120
KNNHLGLGAT INNEDNWIAH QDDFNQLLAE LNTCHGQETT DSSDKKEKKS FSLEEKSKIS
       130        140        150        160        170        180
KNRVHYMKFT KGKDLSSRSK TDLDCIFGKR QSKKTPEGDA SPSTPEENET TTTSAFTIQE
       190        200        210        220        230        240
YFAKRMAALK NKPQVPVPGS DISETQVERK RGKKRNKEAT GKDVESYLQP KAKRHTEGKP
       250        260        270        280        290        300
ERAEAQERVA KKKSAPAEEQ LRGPCWDQSS KASAQDAGDH VQPPEGRDFT LKPKKRRGKK
       310        320
KLQKPVEIAE DATLEETLVK KKKKKDSK

Isoforms

- Isoform 2 of PIN2/TERF1-interacting telomerase inhibitor 1

Sequence View

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Evidence Codes:

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Evidence Names:

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Protein Neighborhood

Domains & Features

3 N-termini - 3 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q96BK5-1-unknown	MSMLAE...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q96BK5-1-unknown	MSMLAE...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt85254
Q96BK5-47-unknown	AQEQGA...	47	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC6658
Q96BK5-47-unknown	AQEQGA...	47	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt138866
Q96BK5-312-unknown	ATLEET...	312	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC13049

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...GKGLGA	46	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC6658
...GKGLGA	46	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt121930
...EIAEDA	311	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC13049
...KKDSK	328	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATL1_HUMAN	46	GLGA.\|.AQEQ	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
GRAB_HUMAN	311	AEDA.\|.ATLE	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Complementary positional proteo... (M14.017)	20526345,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)