O75152: Zinc finger CCCH domain-containing protein 11A

General Information

Protein names	- Zinc finger CCCH domain-containing protein 11A
Gene names	ZC3H11A
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	O75152

10 N-termini

4 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MPNQGEDCYF FFYSTCTKGD SCPFRHCEAA IGNETVCTLW QEGRCFRQVC RFRHMEIDKK
        70         80         90        100        110        120
RSEIPCYWEN QPTGCQKLNC AFHHNRGRYV DGLFLPPSKT VLPTVPESPE EEVKASQLSV
       130        140        150        160        170        180
QQNKLSVQSN PSPQLRSVMK VESSENVPSP THPPVVINAA DDDEDDDDQF SEEGDETKTP
       190        200        210        220        230        240
TLQPTPEVHN GLRVTSVRKP AVNIKQGECL NFGIKTLEEI KSKKMKEKSK KQGEGSSGVS
       250        260        270        280        290        300
SLLLHPEPVP GPEKENVRTV VRTVTLSTKQ GEEPLVRLSL TERLGKRKFS AGGDSDPPLK
       310        320        330        340        350        360
RSLAQRLGKK VEAPETNIDK TPKKAQVSKS LKERLGMSAD PDNEDATDKV NKVGEIHVKT
       370        380        390        400        410        420
LEEILLERAS QKRGELQTKL KTEGPSKTDD STSGARSSST IRIKTFSEVL AEKKHRQQEA
       430        440        450        460        470        480
ERQKSKKDTT CIKLKIDSEI KKTVVLPPIV ASRGQSEEPA GKTKSMQEVH IKTLEEIKLE
       490        500        510        520        530        540
KALRVQQSSE SSTSSPSQHE ATPGARRLLR ITKRTGMKEE KNLQEGNEVD SQSSIRTEAK
       550        560        570        580        590        600
EASGETTGVD ITKIQVKRCE TMREKHMQKQ QEREKSVLTP LRGDVASCNT QVAEKPVLTA
       610        620        630        640        650        660
VPGITRHLTK RLPTKSSQKV EVETSGIGDS LLNVKCAAQT LEKRGKAKPK VNVKPSVVKV
       670        680        690        700        710        720
VSSPKLAPKR KAVEMHAAVI AAVKPLSSSS VLQEPPAKKA AVAVVPLVSE DKSVTVPEAE
       730        740        750        760        770        780
NPRDSLVLPP TQSSSDSSPP EVSGPSSSQM SMKTRRLSSA STGKPPLSVE DDFEKLIWEI
       790        800        810
SGGKLEAEID LDPGKDEDDL LLELSEMIDS

Isoforms

Sequence View

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Evidence Codes:

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Protease Assignment Confidence:

Evidence Names:

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Protein Neighborhood

Domains & Features

10 N-termini - 4 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
O75152-1-unknown	MPNQGE...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
O75152-290-	SAGGDS...	290		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
O75152-336-unknown	GMSADP...	336		unknown			Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
O75152-336-	GMSADP...	336		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
O75152-349-	KVNKVG...	349		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
O75152-349-	KVNKVG...	349		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
O75152-349-	KVNKVG...	349		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
O75152-531-	SQSSIR...	531		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
O75152-682-	AVKPLS...	682		Subtiligase Based Positive Selection		Wells	DB_Untreated	23264352
O75152-682-	AVKPLS...	682		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
O75152-712-unknown	KSVTVP...	712	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC10910
O75152-759-	SASTGK...	759		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
O75152-761-	STGKPP...	761		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...FRQVCR	50	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000406531
...ITKRTG	515	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000415072
...LVSEDK	711	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10910
...EMIDS	810	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAB_HUMAN	711	SEDK.\|.KSVT	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Complementary positional proteo... (M14.017)	20526345,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)