Q12982: BCL2/adenovirus E1B 19 kDa protein-interacting protein 2

General Information

Protein names	- BCL2/adenovirus E1B 19 kDa protein-interacting protein 2
Gene names	BNIP2
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q12982

6 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MEGVELKEEW QDEDFPIPLP EDDSIEADIL AITGPEDQPG SLEVNGNKVR KKLMAPDISL
        70         80         90        100        110        120
TLDPSDGSVL SDDLDESGEI DLDGLDTPSE NSNEFEWEDD LPKPKTTEVI RKGSITEYTA
       130        140        150        160        170        180
AEEKEDGRRW RMFRIGEQDH RVDMKAIEPY KKVISHGGYY GDGLNAIVVF AVCFMPESSQ
       190        200        210        220        230        240
PNYRYLMDNL FKYVIGTLEL LVAENYMIVY LNGATTRRKM PSLGWLRKCY QQIDRRLRKN
       250        260        270        280        290        300
LKSLIIVHPS WFIRTLLAVT RPFISSKFSQ KIRYVFNLAE LAELVPMEYV GIPECIKQVD
       310
QELNGKQDEP KNEQ

Isoforms

- Isoform 2 of BCL2/adenovirus E1B 19 kDa protein-interacting protein 2

Sequence View

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Protein Neighborhood

Domains & Features

6 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q12982-1-unknown	MEGVEL...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q12982-1-unknown	MEGVEL...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt103588
Q12982-29-unknown	ILAITG...	29	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC11991
Q12982-29-unknown	ILAITG...	29	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt141905
Q12982-84-	GLDTPS...	84		Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
Q12982-84-	GLDTPS...	84		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
Q12982-84-	GLDTPS...	84		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q12982-84-	GLDTPS...	84		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q12982-84-	GLDTPS...	84		Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
Q12982-84-	GLDTPS...	84		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
Q12982-84-unknown	GLDTPS...	84	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt165760
Q12982-89-	SENSNE...	89		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q12982-89-	SENSNE...	89		Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
Q12982-89-unknown	SENSNE...	89	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt175403

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...SIEADI	28	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC11991
...SIEADI	28	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt125085
...PKNEQ	314	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...PKNEQ	314	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt64165

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAB_HUMAN	28	EADI.\|.ILAI	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Complementary positional proteo... (M14.017)	20526345,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)