O14602: Eukaryotic translation initiation factor 1A, Y-chromosomal

General Information

Protein names	- Eukaryotic translation initiation factor 1A, Y-chromosomal - eIF-1A Y isoform - Eukaryotic translation initiation factor 4C - eIF-4C
Gene names	EIF1AY
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	O14602

2 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MPKNKGKGGK NRRRGKNENE SEKRELVFKE DGQEYAQVIK MLGNGRLEAL CFDGVKRLCH
        70         80         90        100        110        120
IRGKLRKKVW INTSDIILVG LRDYQDNKAD VILKYNADEA RSLKAYGELP EHAKINETDT
       130        140
FGPGDDDEIQ FDDIGDDDED IDDI

Isoforms

Sequence View

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

2 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
O14602-2-unknown	PKNKGK...	2	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
O14602-2-unknown	PKNKGK...	2	inferred from similarity	unknown	UniProtKB		inferred from uniprot (by similarity)
O14602-2-unknown	PKNKGK...	2		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
O14602-2-unknown	PKNKGK...	2		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
O14602-133-unknown	DIGDDD...	133	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC10667

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...EIQFDD	132	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC10667
	...DIDDI	144	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAB_HUMAN	132	QFDD.\|.DIGD	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Complementary positional proteo... (M14.017)	20526345,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)