Q4G0J3: La-related protein 7

General Information

Protein names	- La-related protein 7 - La ribonucleoprotein domain family member 7 - P-TEFb-interaction protein for 7SK stability - PIP7S
Gene names	LARP7
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q4G0J3

3 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of La-related protein 7 - Isoform 3 of La-related protein 7

Sequence View

        10         20         30         40         50         60
METESGNQEK VMEEESTEKK KEVEKKKRSR VKQVLADIAK QVDFWFGDAN LHKDRFLREQ
        70         80         90        100        110        120
IEKSRDGYVD ISLLVSFNKM KKLTTDGKLI ARALRSSAVV ELDLEGTRIR RKKPLGERPK
       130        140        150        160        170        180
DEDERTVYVE LLPKNVNHSW IERVFGKCGN VVYISIPHYK STGDPKGFAF VEFETKEQAA
       190        200        210        220        230        240
KAIEFLNNPP EEAPRKPGIF PKTVKNKPIP ALRVVEEKKK KKKKKGRMKK EDNIQAKEEN
       250        260        270        280        290        300
MDTSNTSISK MKRSRPTSEG SDIESTEPQK QCSKKKKKRD RVEASSLPEV RTGKRKRSSS
       310        320        330        340        350        360
EDAESLAPRS KVKKIIQKDI IKEASEASKE NRDIEISTEE EKDTGDLKDS SLLKTKRKHK
       370        380        390        400        410        420
KKHKERHKMG EEVIPLRVLS KSEWMDLKKE YLALQKASMA SLKKTISQIK SESEMETDSG
       430        440        450        460        470        480
VPQNTGMKNE KTANREECRT QEKVNATGPQ FVSGVIVKII STEPLPGRKQ VRDTLAAISE
       490        500        510        520        530        540
VLYVDLLEGD TECHARFKTP EDAQAVINAY TEINKKHCWK LEILSGDHEQ RYWQKILVDR
       550        560        570        580
QAKLNQPREK KRGTEKLITK AEKIRLAKTQ QASKHIRFSE YD         10         20         30         40         50         60
METESGNQEK VMEEESTEKK KEVEKKKRSR VKQVLADIAK QVDFWFGDAN LHKDRFLREQ
        70         80         90        100        110        120
IEKSRDGYVD ISLLVSFNKM KKLTTDGKLI ARALRSSAVV ELDLEGTRIR RKKPLGERPK
       130        140        150        160        170        180
DEDERTVYVE LLPKNVNHSW IERVFGKCGN VVYISIPHYK STGDPKGFAF VEFETKEQAA
       190        200        210        220        230        240
KAIEFLNNPP EEAPRKPGIF PKTVKNKPIP ALRVVEEKKK KKKKKGRMKK EDNIQAKEEN
       250        260        270        280        290        300
MDTSNTSISK MKRSRPTSEG SDIESTEPQK QCSKKKKKRD RVEASSLPEV RTGKRKRSSS
       310        320        330        340        350        360
EDAESLAPRS KVKKIIQKDI IKEASEASKE NRDIEISTEE EKDTGDLKDS SLLKTKRKHK
       370        380        390        400        410        420
KKHKERHKMG EEVIPLRVLS KSEWMDLKKE YLALQKASMA SLKKTISQIK SESEMETDSG
       430        440        450        460        470        480
VPQNTGMKNE KTANREECRT QEKVNATGPQ FVSGVIVKII STEPLPGRKQ VRDTLAAISE
       490        500        510        520        530        540
VLYVDLLEGD TECHARFKTP EDAQAVINAY TEINKKHCWK LEILSGDHEQ RYWQKILVDR
       550        560        570        580
QAKLNQPREK KRGTEKLITK AEKIRLAKTQ QASKHIRFSE YD

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

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Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

3 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q4G0J3-1-Acetylation	METESG...	1	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q4G0J3-1-Acetylation	METESG...	1	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
Q4G0J3-1-Acetylation	METESG...	1	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt101228
Q4G0J3-369-unknown	MGEEVI...	369		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt79389
Q4G0J3-369-unknown	MGEEVI...	369		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt97547
Q4G0J3-419-unknown	SGVPQN...	419		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC12450
Q4G0J3-419-unknown	SGVPQN...	419		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt139280
Q4G0J3-419-unknown	SGVPQN...	419		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt152429

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...EMETDS	418	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC12450
...EMETDS	418	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt122355
...EMETDS	418	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt135839
...FSEYD	582	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...FSEYD	582	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt75007
...FSEYD	582	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt75008

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAB_HUMAN	418	ETDS.\|.SGVP	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Complementary positional proteo... (M14.017)	20526345,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)