Q9UHR6: Zinc finger HIT domain-containing protein 2

General Information

Protein names	- Zinc finger HIT domain-containing protein 2 - Protein FON
Gene names	ZNHIT2
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9UHR6

3 N-termini

3 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MEPAGPCGFC PAGEVQPARY TCPRCNAPYC SLRCYRTHGT CAENFYRDQV LGELRGCSAP
        70         80         90        100        110        120
PSRLASALRR LRQQRETEDE PGEAGLSSGP APGGLSGLWE RLAPGEKAAF ERLLSRGEAG
       130        140        150        160        170        180
RLLPPWRPWW WNRGAGPQLL EELDNAPGSD AAELELAPAR TPPDSVKDAS AAEPAAAERV
       190        200        210        220        230        240
LGDVPGACTP VVPTRIPAIV SLSRGPVSPL VRFQLPNVLF AYAHTLALYH GGDDALLSDF
       250        260        270        280        290        300
CATLLGVSGA LGAQQVFASA EEALQAAAHV LEAGEHPPGP LGTRGAMHEV ARILLGEGPT
       310        320        330        340        350        360
NQKGYTLAAL GDLAQTLGRA RKQAVAREER DHLYRARKKC QFLLAWTNEN EAALTPLALD
       370        380        390        400
CARAHQAHAV VAEEVAALTG ELERLWGGPV PPAPRTLIEE LPS

Isoforms

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

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Biological System:

Protease Assignment Confidence:

Evidence Names:

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Protein Neighborhood

Domains & Features

3 N-termini - 3 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q9UHR6-1-Acetylation	MEPAGP...	1	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9UHR6-1-Acetylation	MEPAGP...	1	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
Q9UHR6-1-Acetylation	MEPAGP...	1	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
Q9UHR6-145-	NAPGSD...	145			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q9UHR6-145-	NAPGSD...	145			Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q9UHR6-151-unknown	AAELEL...	151		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC13531

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
...APGSDA	150	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC13531
...TNENEA	351	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000436896
...EELPS	403	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
...EELPS	403		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...EELPS	403		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAB_HUMAN	150	GSDA.\|.AAEL	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Complementary positional proteo... (M14.017)	20526345,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)