Q5JSZ5: Protein PRRC2B
Protein names | - Protein PRRC2B - HLA-B-associated transcript 2-like 1 - Proline-rich coiled-coil protein 2B |
---|---|
Gene names | PRRC2B |
Organism | Homo sapiens |
Protease Family | |
Protease ID | |
Chromosome location | |
UniProt ID | Q5JSZ5 |
9
N-termini
5
C-termini
3
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MSDRLGQITK GKDGKSKYST LSLFDKYKGK SVDAIRSSVI PRHGLQSLGK VAAARRMPPP
70 80 90 100 110 120
ANLPSLKSEN KGNDPNIVIV PKDGTGWANK QDQQDPKSSS ATASQPPESL PQPGLQKSVS
130 140 150 160 170 180
NLQKPTQSIS QENTNSVPGG PKSWAQLNGK PVGHEGGLRG SSRLLSFSPE EFPTLKAAGG
190 200 210 220 230 240
QDKAGKEKGV LDLSYGPGPS LRPQNVTSWR EGGGRHIISA TSLSTSPTEL GSRNSSTGDG
250 260 270 280 290 300
APSSACTSDS KDPSLRPAQP VRKGASQFMG NVYHPPTYHD MLPAFMCSPK SSENQGTVER
310 320 330 340 350 360
GSFPLPQLRL EPRVPFRQFQ MNDQDGKENR LGLSRPLRPL RQLVERAPRP TIINAENLKG
370 380 390 400 410 420
LDDLDADADD GWAGLHEEVD YSEKLKFSDD EEEEEVVKDG RPKWNSWDPR RQRQLSMSSA
430 440 450 460 470 480
DSADAKRTRE EGKDWAEAVG ASRVVRKAPD PQPPPRKLHG WAPGPDYQKS SMGSMFRQQS
490 500 510 520 530 540
IEDKEDKPPP RQKFIQSEMS EAVERARKRR EEEERRAREE RLAACAAKLK QLDQKCKQAR
550 560 570 580 590 600
KAGEARKQAE KEVPWSPSAE KASPQENGPA VHKGSPEFPA QETPTTFPEE APTVSPAVAQ
610 620 630 640 650 660
SNSSEEEARE AGSPAQEFKY QKSLPPRFQR QQQQQQQEQL YKMQHWQPVY PPPSHPQRTF
670 680 690 700 710 720
YPHHPQMLGF DPRWMMMPSY MDPRITPTRT PVDFYPSALH PSGLMKPMMP QESLNGTGCR
730 740 750 760 770 780
SEDQNCVPPL QERKVTPIDS PPVWSPEGYM ALQSKGYPLP HPKSSDTLAM DMRVRNESSF
790 800 810 820 830 840
SASLGRAGGV SAQRDLFEER GEEYLSAFDK KAQADFDSCI SSQRIGQELL FPPQENVQDA
850 860 870 880 890 900
GAPGGHTQNL RCSPLEPDFV PDEKKPECGS WDVSHQPETA DTAHGVERET PREGTAFNIS
910 920 930 940 950 960
SWDKNGSPNK QPSSEPEWTP EPRSSSSQHP EQTGRTRRSG PIKKPVLKAL KVEDKEKELE
970 980 990 1000 1010 1020
KIKQELGEES TRLAKEKEQS PTAEKDEDEE NDASLANSST TTLEDKGPGH ATFGREATKF
1030 1040 1050 1060 1070 1080
EEEEKPDKAW EARPPRESSD VPPMKRNNWI FIDEEQAFGV RGQARGRGRG FREFTFRGRP
1090 1100 1110 1120 1130 1140
AGGNGSGLCG GGVLGARSIY CSSQRSGRGR GLREFARPED CPRAKPRRRV ASETHSEGSE
1150 1160 1170 1180 1190 1200
YEELPKRRRQ RGSENGNEGS LLEREESTLK KGDCRDSWRS NKGCSEDHSG LDAKSRGPRA
1210 1220 1230 1240 1250 1260
FGRALPPRLS NCGYGRRTFV SKESPHWQSK SPGSSWQEYG PSDTCGSRRP TDRDYVPDSY
1270 1280 1290 1300 1310 1320
RHPDAFGGRG FEDSRAEDKR SFFQDEHVAD SENAENRPFR RRRPPRQDKP PRFRRLRQER
1330 1340 1350 1360 1370 1380
ESLGLWGPEE EPHLLAGQWP GRPKLCSGDK SGTVGRRSPE LSYQNSSDHA NEEWETASES
1390 1400 1410 1420 1430 1440
SDFSERRERR EGPGSEPDSQ VDGGLSGASL GEKKELAKRS FSSQRPVVDR QSRKLEPGGF
1450 1460 1470 1480 1490 1500
GEKPVRPGGG DTSPRYESQQ NGTPLKVKRS PDEALPGGLS GCSSGSGHSP YALERAAHAS
1510 1520 1530 1540 1550 1560
ADLPEASSKK AEKEAKLAAP RAGEQGEAMK QFDLNYGSAI IENCGSSPGE ESEVGSMVGE
1570 1580 1590 1600 1610 1620
GFIEVLTKKQ RRLLEEERRK KEQAVQVPVK GRGLSSRIPP RFAKKQNNLC LEQGDVTVPG
1630 1640 1650 1660 1670 1680
SSLGTEIWES SSQALPVQAP ANDSWRKAVT AFSSTETGSA EQGFKSSQGD SGVDLSAESR
1690 1700 1710 1720 1730 1740
ESSATSSQRS SPYGTLKPEE MSGPGLAEPK ADSHKEQAPK PSEQKDSEQG SGQSKEHRPG
1750 1760 1770 1780 1790 1800
PIGNERSLKN RKGSEGAERL QGAVVPPVNG VEIHVDSVLP VPPIEFGVSP KDSDFSLPPG
1810 1820 1830 1840 1850 1860
SASGPTGSPV VKLQDALASN AGLTQSIPIL RRDHHIQRAI GLSPMSFPTA DLTLKMESAR
1870 1880 1890 1900 1910 1920
KAWENSPSLP EQSSPGGAGS GIQPPSSVGA SSGVNYSSFG GVSMPPMPVA SVAPSASMPG
1930 1940 1950 1960 1970 1980
SHLPPLYLDG HVFASQPRLV PQTIPQQQSY QQAAAAQQIP ISLHTSLQAQ AQLGLRGGLP
1990 2000 2010 2020 2030 2040
VSQSQEIFSS LQPFRSQVYM HPSLSPPSTM ILSGGTALKP PYSAFPGMQP LEMVKPQSGS
2050 2060 2070 2080 2090 2100
PYQPMSGNQA LVYEGQLSQA AGLGASQMLD SQLPQLTMPL PRYGSGQQPL ILPQSIQLPP
2110 2120 2130 2140 2150 2160
GQSLSVGAPR RIPPPGSQPP VLNTSREPSQ MEMKGFHFAD SKQNVPSGGP VPSPQTYRPS
2170 2180 2190 2200 2210 2220
SASPSGKPSG SAVNMGSVQG HYVQQAKQRV DEKPSLGAVK LQEAPSAASQ MKRTGAIKPR
AVKVEESKA
Isoforms
- Isoform 2 of Protein PRRC2B - Isoform 3 of Protein PRRC2B - Isoform 4 of Protein PRRC2B - Isoform 1 of Protein PRRC2BSequence View
10 20 30 40 50 60
MSDRLGQITK GKDGKSKYST LSLFDKYKGK SVDAIRSSVI PRHGLQSLGK VAAARRMPPP
70 80 90 100 110 120
ANLPSLKSEN KGNDPNIVIV PKDGTGWANK QDQQDPKSSS ATASQPPESL PQPGLQKSVS
130 140 150 160 170 180
NLQKPTQSIS QENTNSVPGG PKSWAQLNGK PVGHEGGLRG SSRLLSFSPE EFPTLKAAGG
190 200 210 220 230 240
QDKAGKEKGV LDLSYGPGPS LRPQNVTSWR EGGGRHIISA TSLSTSPTEL GSRNSSTGDG
250 260 270 280 290 300
APSSACTSDS KDPSLRPAQP VRKGASQFMG NVYHPPTYHD MLPAFMCSPK SSENQGTVER
310 320 330 340 350 360
GSFPLPQLRL EPRVPFRQFQ MNDQDGKENR LGLSRPLRPL RQLVERAPRP TIINAENLKG
370 380 390 400 410 420
LDDLDADADD GWAGLHEEVD YSEKLKFSDD EEEEEVVKDG RPKWNSWDPR RQRQLSMSSA
430 440 450 460 470 480
DSADAKRTRE EGKDWAEAVG ASRVVRKAPD PQPPPRKLHG WAPGPDYQKS SMGSMFRQQS
490 500 510 520 530 540
IEDKEDKPPP RQKFIQSEMS EAVERARKRR EEEERRAREE RLAACAAKLK QLDQKCKQAR
550 560 570 580 590 600
KAGEARKQAE KEVPWSPSAE KASPQENGPA VHKGSPEFPA QETPTTFPEE APTVSPAVAQ
610 620 630 640 650 660
SNSSEEEARE AGSPAQEFKY QKSLPPRFQR QQQQQQQEQL YKMQHWQPVY PPPSHPQRTF
670 680 690 700 710 720
YPHHPQMLGF DPRWMMMPSY MDPRITPTRT PVDFYPSALH PSGLMKPMMP QESLNGTGCR
730 740 750 760 770 780
SEDQNCVPPL QERKVTPIDS PPVWSPEGYM ALQSKGYPLP HPKSSDTLAM DMRVRNESSF
790 800 810 820 830 840
SASLGRAGGV SAQRDLFEER GEEYLSAFDK KAQADFDSCI SSQRIGQELL FPPQENVQDA
850 860 870 880 890 900
GAPGGHTQNL RCSPLEPDFV PDEKKPECGS WDVSHQPETA DTAHGVERET PREGTAFNIS
910 920 930 940 950 960
SWDKNGSPNK QPSSEPEWTP EPRSSSSQHP EQTGRTRRSG PIKKPVLKAL KVEDKEKELE
970 980 990 1000 1010 1020
KIKQELGEES TRLAKEKEQS PTAEKDEDEE NDASLANSST TTLEDKGPGH ATFGREATKF
1030 1040 1050 1060 1070 1080
EEEEKPDKAW EARPPRESSD VPPMKRNNWI FIDEEQAFGV RGQARGRGRG FREFTFRGRP
1090 1100 1110 1120 1130 1140
AGGNGSGLCG GGVLGARSIY CSSQRSGRGR GLREFARPED CPRAKPRRRV ASETHSEGSE
1150 1160 1170 1180 1190 1200
YEELPKRRRQ RGSENGNEGS LLEREESTLK KGDCRDSWRS NKGCSEDHSG LDAKSRGPRA
1210 1220 1230 1240 1250 1260
FGRALPPRLS NCGYGRRTFV SKESPHWQSK SPGSSWQEYG PSDTCGSRRP TDRDYVPDSY
1270 1280 1290 1300 1310 1320
RHPDAFGGRG FEDSRAEDKR SFFQDEHVAD SENAENRPFR RRRPPRQDKP PRFRRLRQER
1330 1340 1350 1360 1370 1380
ESLGLWGPEE EPHLLAGQWP GRPKLCSGDK SGTVGRRSPE LSYQNSSDHA NEEWETASES
1390 1400 1410 1420 1430 1440
SDFSERRERR EGPGSEPDSQ VDGGLSGASL GEKKELAKRS FSSQRPVVDR QSRKLEPGGF
1450 1460 1470 1480 1490 1500
GEKPVRPGGG DTSPRYESQQ NGTPLKVKRS PDEALPGGLS GCSSGSGHSP YALERAAHAS
1510 1520 1530 1540 1550 1560
ADLPEASSKK AEKEAKLAAP RAGEQGEAMK QFDLNYGSAI IENCGSSPGE ESEVGSMVGE
1570 1580 1590 1600 1610 1620
GFIEVLTKKQ RRLLEEERRK KEQAVQVPVK GRGLSSRIPP RFAKKQNNLC LEQGDVTVPG
1630 1640 1650 1660 1670 1680
SSLGTEIWES SSQALPVQAP ANDSWRKAVT AFSSTETGSA EQGFKSSQGD SGVDLSAESR
1690 1700 1710 1720 1730 1740
ESSATSSQRS SPYGTLKPEE MSGPGLAEPK ADSHKEQAPK PSEQKDSEQG SGQSKEHRPG
1750 1760 1770 1780 1790 1800
PIGNERSLKN RKGSEGAERL QGAVVPPVNG VEIHVDSVLP VPPIEFGVSP KDSDFSLPPG
1810 1820 1830 1840 1850 1860
SASGPTGSPV VKLQDALASN AGLTQSIPIL RRDHHIQRAI GLSPMSFPTA DLTLKMESAR
1870 1880 1890 1900 1910 1920
KAWENSPSLP EQSSPGGAGS GIQPPSSVGA SSGVNYSSFG GVSMPPMPVA SVAPSASMPG
1930 1940 1950 1960 1970 1980
SHLPPLYLDG HVFASQPRLV PQTIPQQQSY QQAAAAQQIP ISLHTSLQAQ AQLGLRGGLP
1990 2000 2010 2020 2030 2040
VSQSQEIFSS LQPFRSQVYM HPSLSPPSTM ILSGGTALKP PYSAFPGMQP LEMVKPQSGS
2050 2060 2070 2080 2090 2100
PYQPMSGNQA LVYEGQLSQA AGLGASQMLD SQLPQLTMPL PRYGSGQQPL ILPQSIQLPP
2110 2120 2130 2140 2150 2160
GQSLSVGAPR RIPPPGSQPP VLNTSREPSQ MEMKGFHFAD SKQNVPSGGP VPSPQTYRPS
2170 2180 2190 2200 2210 2220
SASPSGKPSG SAVNMGSVQG HYVQQAKQRV DEKPSLGAVK LQEAPSAASQ MKRTGAIKPR
AVKVEESKA
10 20 30 40 50 60
MSDRLGQITK GKDGKSKYST LSLFDKYKGK SVDAIRSSVI PRHGLQSLGK VAAARRMPPP
70 80 90 100 110 120
ANLPSLKSEN KGNDPNIVIV PKDGTGWANK QDQQDPKSSS ATASQPPESL PQPGLQKSVS
130 140 150 160 170 180
NLQKPTQSIS QENTNSVPGG PKSWAQLNGK PVGHEGGLRG SSRLLSFSPE EFPTLKAAGG
190 200 210 220 230 240
QDKAGKEKGV LDLSYGPGPS LRPQNVTSWR EGGGRHIISA TSLSTSPTEL GSRNSSTGDG
250 260 270 280 290 300
APSSACTSDS KDPSLRPAQP VRKGASQFMG NVYHPPTYHD MLPAFMCSPK SSENQGTVER
310 320 330 340 350 360
GSFPLPQLRL EPRVPFRQFQ MNDQDGKENR LGLSRPLRPL RQLVERAPRP TIINAENLKG
370 380 390 400 410 420
LDDLDADADD GWAGLHEEVD YSEKLKFSDD EEEEEVVKDG RPKWNSWDPR RQRQLSMSSA
430 440 450 460 470 480
DSADAKRTRE EGKDWAEAVG ASRVVRKAPD PQPPPRKLHG WAPGPDYQKS SMGSMFRQQS
490 500 510 520 530 540
IEDKEDKPPP RQKFIQSEMS EAVERARKRR EEEERRAREE RLAACAAKLK QLDQKCKQAR
550 560 570 580 590 600
KAGEARKQAE KEVPWSPSAE KASPQENGPA VHKGSPEFPA QETPTTFPEE APTVSPAVAQ
610 620 630 640 650 660
SNSSEEEARE AGSPAQEFKY QKSLPPRFQR QQQQQQQEQL YKMQHWQPVY PPPSHPQRTF
670 680 690 700 710 720
YPHHPQMLGF DPRWMMMPSY MDPRITPTRT PVDFYPSALH PSGLMKPMMP QESLNGTGCR
730 740 750 760 770 780
SEDQNCVPPL QERKVTPIDS PPVWSPEGYM ALQSKGYPLP HPKSSDTLAM DMRVRNESSF
790 800 810 820 830 840
SASLGRAGGV SAQRDLFEER GEEYLSAFDK KAQADFDSCI SSQRIGQELL FPPQENVQDA
850 860 870 880 890 900
GAPGGHTQNL RCSPLEPDFV PDEKKPECGS WDVSHQPETA DTAHGVERET PREGTAFNIS
910 920 930 940 950 960
SWDKNGSPNK QPSSEPEWTP EPRSSSSQHP EQTGRTRRSG PIKKPVLKAL KVEDKEKELE
970 980 990 1000 1010 1020
KIKQELGEES TRLAKEKEQS PTAEKDEDEE NDASLANSST TTLEDKGPGH ATFGREATKF
1030 1040 1050 1060 1070 1080
EEEEKPDKAW EARPPRESSD VPPMKRNNWI FIDEEQAFGV RGQARGRGRG FREFTFRGRP
1090 1100 1110 1120 1130 1140
AGGNGSGLCG GGVLGARSIY CSSQRSGRGR GLREFARPED CPRAKPRRRV ASETHSEGSE
1150 1160 1170 1180 1190 1200
YEELPKRRRQ RGSENGNEGS LLEREESTLK KGDCRDSWRS NKGCSEDHSG LDAKSRGPRA
1210 1220 1230 1240 1250 1260
FGRALPPRLS NCGYGRRTFV SKESPHWQSK SPGSSWQEYG PSDTCGSRRP TDRDYVPDSY
1270 1280 1290 1300 1310 1320
RHPDAFGGRG FEDSRAEDKR SFFQDEHVAD SENAENRPFR RRRPPRQDKP PRFRRLRQER
1330 1340 1350 1360 1370 1380
ESLGLWGPEE EPHLLAGQWP GRPKLCSGDK SGTVGRRSPE LSYQNSSDHA NEEWETASES
1390 1400 1410 1420 1430 1440
SDFSERRERR EGPGSEPDSQ VDGGLSGASL GEKKELAKRS FSSQRPVVDR QSRKLEPGGF
1450 1460 1470 1480 1490 1500
GEKPVRPGGG DTSPRYESQQ NGTPLKVKRS PDEALPGGLS GCSSGSGHSP YALERAAHAS
1510 1520 1530 1540 1550 1560
ADLPEASSKK AEKEAKLAAP RAGEQGEAMK QFDLNYGSAI IENCGSSPGE ESEVGSMVGE
1570 1580 1590 1600 1610 1620
GFIEVLTKKQ RRLLEEERRK KEQAVQVPVK GRGLSSRIPP RFAKKQNNLC LEQGDVTVPG
1630 1640 1650 1660 1670 1680
SSLGTEIWES SSQALPVQAP ANDSWRKAVT AFSSTETGSA EQGFKSSQGD SGVDLSAESR
1690 1700 1710 1720 1730 1740
ESSATSSQRS SPYGTLKPEE MSGPGLAEPK ADSHKEQAPK PSEQKDSEQG SGQSKEHRPG
1750 1760 1770 1780 1790 1800
PIGNERSLKN RKGSEGAERL QGAVVPPVNG VEIHVDSVLP VPPIEFGVSP KDSDFSLPPG
1810 1820 1830 1840 1850 1860
SASGPTGSPV VKLQDALASN AGLTQSIPIL RRDHHIQRAI GLSPMSFPTA DLTLKMESAR
1870 1880 1890 1900 1910 1920
KAWENSPSLP EQSSPGGAGS GIQPPSSVGA SSGVNYSSFG GVSMPPMPVA SVAPSASMPG
1930 1940 1950 1960 1970 1980
SHLPPLYLDG HVFASQPRLV PQTIPQQQSY QQAAAAQQIP ISLHTSLQAQ AQLGLRGGLP
1990 2000 2010 2020 2030 2040
VSQSQEIFSS LQPFRSQVYM HPSLSPPSTM ILSGGTALKP PYSAFPGMQP LEMVKPQSGS
2050 2060 2070 2080 2090 2100
PYQPMSGNQA LVYEGQLSQA AGLGASQMLD SQLPQLTMPL PRYGSGQQPL ILPQSIQLPP
2110 2120 2130 2140 2150 2160
GQSLSVGAPR RIPPPGSQPP VLNTSREPSQ MEMKGFHFAD SKQNVPSGGP VPSPQTYRPS
2170 2180 2190 2200 2210 2220
SASPSGKPSG SAVNMGSVQG HYVQQAKQRV DEKPSLGAVK LQEAPSAASQ MKRTGAIKPR
AVKVEESKA
10 20 30 40 50 60
MSDRLGQITK GKDGKSKYST LSLFDKYKGK SVDAIRSSVI PRHGLQSLGK VAAARRMPPP
70 80 90 100 110 120
ANLPSLKSEN KGNDPNIVIV PKDGTGWANK QDQQDPKSSS ATASQPPESL PQPGLQKSVS
130 140 150 160 170 180
NLQKPTQSIS QENTNSVPGG PKSWAQLNGK PVGHEGGLRG SSRLLSFSPE EFPTLKAAGG
190 200 210 220 230 240
QDKAGKEKGV LDLSYGPGPS LRPQNVTSWR EGGGRHIISA TSLSTSPTEL GSRNSSTGDG
250 260 270 280 290 300
APSSACTSDS KDPSLRPAQP VRKGASQFMG NVYHPPTYHD MLPAFMCSPK SSENQGTVER
310 320 330 340 350 360
GSFPLPQLRL EPRVPFRQFQ MNDQDGKENR LGLSRPLRPL RQLVERAPRP TIINAENLKG
370 380 390 400 410 420
LDDLDADADD GWAGLHEEVD YSEKLKFSDD EEEEEVVKDG RPKWNSWDPR RQRQLSMSSA
430 440 450 460 470 480
DSADAKRTRE EGKDWAEAVG ASRVVRKAPD PQPPPRKLHG WAPGPDYQKS SMGSMFRQQS
490 500 510 520 530 540
IEDKEDKPPP RQKFIQSEMS EAVERARKRR EEEERRAREE RLAACAAKLK QLDQKCKQAR
550 560 570 580 590 600
KAGEARKQAE KEVPWSPSAE KASPQENGPA VHKGSPEFPA QETPTTFPEE APTVSPAVAQ
610 620 630 640 650 660
SNSSEEEARE AGSPAQEFKY QKSLPPRFQR QQQQQQQEQL YKMQHWQPVY PPPSHPQRTF
670 680 690 700 710 720
YPHHPQMLGF DPRWMMMPSY MDPRITPTRT PVDFYPSALH PSGLMKPMMP QESLNGTGCR
730 740 750 760 770 780
SEDQNCVPPL QERKVTPIDS PPVWSPEGYM ALQSKGYPLP HPKSSDTLAM DMRVRNESSF
790 800 810 820 830 840
SASLGRAGGV SAQRDLFEER GEEYLSAFDK KAQADFDSCI SSQRIGQELL FPPQENVQDA
850 860 870 880 890 900
GAPGGHTQNL RCSPLEPDFV PDEKKPECGS WDVSHQPETA DTAHGVERET PREGTAFNIS
910 920 930 940 950 960
SWDKNGSPNK QPSSEPEWTP EPRSSSSQHP EQTGRTRRSG PIKKPVLKAL KVEDKEKELE
970 980 990 1000 1010 1020
KIKQELGEES TRLAKEKEQS PTAEKDEDEE NDASLANSST TTLEDKGPGH ATFGREATKF
1030 1040 1050 1060 1070 1080
EEEEKPDKAW EARPPRESSD VPPMKRNNWI FIDEEQAFGV RGQARGRGRG FREFTFRGRP
1090 1100 1110 1120 1130 1140
AGGNGSGLCG GGVLGARSIY CSSQRSGRGR GLREFARPED CPRAKPRRRV ASETHSEGSE
1150 1160 1170 1180 1190 1200
YEELPKRRRQ RGSENGNEGS LLEREESTLK KGDCRDSWRS NKGCSEDHSG LDAKSRGPRA
1210 1220 1230 1240 1250 1260
FGRALPPRLS NCGYGRRTFV SKESPHWQSK SPGSSWQEYG PSDTCGSRRP TDRDYVPDSY
1270 1280 1290 1300 1310 1320
RHPDAFGGRG FEDSRAEDKR SFFQDEHVAD SENAENRPFR RRRPPRQDKP PRFRRLRQER
1330 1340 1350 1360 1370 1380
ESLGLWGPEE EPHLLAGQWP GRPKLCSGDK SGTVGRRSPE LSYQNSSDHA NEEWETASES
1390 1400 1410 1420 1430 1440
SDFSERRERR EGPGSEPDSQ VDGGLSGASL GEKKELAKRS FSSQRPVVDR QSRKLEPGGF
1450 1460 1470 1480 1490 1500
GEKPVRPGGG DTSPRYESQQ NGTPLKVKRS PDEALPGGLS GCSSGSGHSP YALERAAHAS
1510 1520 1530 1540 1550 1560
ADLPEASSKK AEKEAKLAAP RAGEQGEAMK QFDLNYGSAI IENCGSSPGE ESEVGSMVGE
1570 1580 1590 1600 1610 1620
GFIEVLTKKQ RRLLEEERRK KEQAVQVPVK GRGLSSRIPP RFAKKQNNLC LEQGDVTVPG
1630 1640 1650 1660 1670 1680
SSLGTEIWES SSQALPVQAP ANDSWRKAVT AFSSTETGSA EQGFKSSQGD SGVDLSAESR
1690 1700 1710 1720 1730 1740
ESSATSSQRS SPYGTLKPEE MSGPGLAEPK ADSHKEQAPK PSEQKDSEQG SGQSKEHRPG
1750 1760 1770 1780 1790 1800
PIGNERSLKN RKGSEGAERL QGAVVPPVNG VEIHVDSVLP VPPIEFGVSP KDSDFSLPPG
1810 1820 1830 1840 1850 1860
SASGPTGSPV VKLQDALASN AGLTQSIPIL RRDHHIQRAI GLSPMSFPTA DLTLKMESAR
1870 1880 1890 1900 1910 1920
KAWENSPSLP EQSSPGGAGS GIQPPSSVGA SSGVNYSSFG GVSMPPMPVA SVAPSASMPG
1930 1940 1950 1960 1970 1980
SHLPPLYLDG HVFASQPRLV PQTIPQQQSY QQAAAAQQIP ISLHTSLQAQ AQLGLRGGLP
1990 2000 2010 2020 2030 2040
VSQSQEIFSS LQPFRSQVYM HPSLSPPSTM ILSGGTALKP PYSAFPGMQP LEMVKPQSGS
2050 2060 2070 2080 2090 2100
PYQPMSGNQA LVYEGQLSQA AGLGASQMLD SQLPQLTMPL PRYGSGQQPL ILPQSIQLPP
2110 2120 2130 2140 2150 2160
GQSLSVGAPR RIPPPGSQPP VLNTSREPSQ MEMKGFHFAD SKQNVPSGGP VPSPQTYRPS
2170 2180 2190 2200 2210 2220
SASPSGKPSG SAVNMGSVQG HYVQQAKQRV DEKPSLGAVK LQEAPSAASQ MKRTGAIKPR
AVKVEESKA
10 20 30 40 50 60
MSDRLGQITK GKDGKSKYST LSLFDKYKGK SVDAIRSSVI PRHGLQSLGK VAAARRMPPP
70 80 90 100 110 120
ANLPSLKSEN KGNDPNIVIV PKDGTGWANK QDQQDPKSSS ATASQPPESL PQPGLQKSVS
130 140 150 160 170 180
NLQKPTQSIS QENTNSVPGG PKSWAQLNGK PVGHEGGLRG SSRLLSFSPE EFPTLKAAGG
190 200 210 220 230 240
QDKAGKEKGV LDLSYGPGPS LRPQNVTSWR EGGGRHIISA TSLSTSPTEL GSRNSSTGDG
250 260 270 280 290 300
APSSACTSDS KDPSLRPAQP VRKGASQFMG NVYHPPTYHD MLPAFMCSPK SSENQGTVER
310 320 330 340 350 360
GSFPLPQLRL EPRVPFRQFQ MNDQDGKENR LGLSRPLRPL RQLVERAPRP TIINAENLKG
370 380 390 400 410 420
LDDLDADADD GWAGLHEEVD YSEKLKFSDD EEEEEVVKDG RPKWNSWDPR RQRQLSMSSA
430 440 450 460 470 480
DSADAKRTRE EGKDWAEAVG ASRVVRKAPD PQPPPRKLHG WAPGPDYQKS SMGSMFRQQS
490 500 510 520 530 540
IEDKEDKPPP RQKFIQSEMS EAVERARKRR EEEERRAREE RLAACAAKLK QLDQKCKQAR
550 560 570 580 590 600
KAGEARKQAE KEVPWSPSAE KASPQENGPA VHKGSPEFPA QETPTTFPEE APTVSPAVAQ
610 620 630 640 650 660
SNSSEEEARE AGSPAQEFKY QKSLPPRFQR QQQQQQQEQL YKMQHWQPVY PPPSHPQRTF
670 680 690 700 710 720
YPHHPQMLGF DPRWMMMPSY MDPRITPTRT PVDFYPSALH PSGLMKPMMP QESLNGTGCR
730 740 750 760 770 780
SEDQNCVPPL QERKVTPIDS PPVWSPEGYM ALQSKGYPLP HPKSSDTLAM DMRVRNESSF
790 800 810 820 830 840
SASLGRAGGV SAQRDLFEER GEEYLSAFDK KAQADFDSCI SSQRIGQELL FPPQENVQDA
850 860 870 880 890 900
GAPGGHTQNL RCSPLEPDFV PDEKKPECGS WDVSHQPETA DTAHGVERET PREGTAFNIS
910 920 930 940 950 960
SWDKNGSPNK QPSSEPEWTP EPRSSSSQHP EQTGRTRRSG PIKKPVLKAL KVEDKEKELE
970 980 990 1000 1010 1020
KIKQELGEES TRLAKEKEQS PTAEKDEDEE NDASLANSST TTLEDKGPGH ATFGREATKF
1030 1040 1050 1060 1070 1080
EEEEKPDKAW EARPPRESSD VPPMKRNNWI FIDEEQAFGV RGQARGRGRG FREFTFRGRP
1090 1100 1110 1120 1130 1140
AGGNGSGLCG GGVLGARSIY CSSQRSGRGR GLREFARPED CPRAKPRRRV ASETHSEGSE
1150 1160 1170 1180 1190 1200
YEELPKRRRQ RGSENGNEGS LLEREESTLK KGDCRDSWRS NKGCSEDHSG LDAKSRGPRA
1210 1220 1230 1240 1250 1260
FGRALPPRLS NCGYGRRTFV SKESPHWQSK SPGSSWQEYG PSDTCGSRRP TDRDYVPDSY
1270 1280 1290 1300 1310 1320
RHPDAFGGRG FEDSRAEDKR SFFQDEHVAD SENAENRPFR RRRPPRQDKP PRFRRLRQER
1330 1340 1350 1360 1370 1380
ESLGLWGPEE EPHLLAGQWP GRPKLCSGDK SGTVGRRSPE LSYQNSSDHA NEEWETASES
1390 1400 1410 1420 1430 1440
SDFSERRERR EGPGSEPDSQ VDGGLSGASL GEKKELAKRS FSSQRPVVDR QSRKLEPGGF
1450 1460 1470 1480 1490 1500
GEKPVRPGGG DTSPRYESQQ NGTPLKVKRS PDEALPGGLS GCSSGSGHSP YALERAAHAS
1510 1520 1530 1540 1550 1560
ADLPEASSKK AEKEAKLAAP RAGEQGEAMK QFDLNYGSAI IENCGSSPGE ESEVGSMVGE
1570 1580 1590 1600 1610 1620
GFIEVLTKKQ RRLLEEERRK KEQAVQVPVK GRGLSSRIPP RFAKKQNNLC LEQGDVTVPG
1630 1640 1650 1660 1670 1680
SSLGTEIWES SSQALPVQAP ANDSWRKAVT AFSSTETGSA EQGFKSSQGD SGVDLSAESR
1690 1700 1710 1720 1730 1740
ESSATSSQRS SPYGTLKPEE MSGPGLAEPK ADSHKEQAPK PSEQKDSEQG SGQSKEHRPG
1750 1760 1770 1780 1790 1800
PIGNERSLKN RKGSEGAERL QGAVVPPVNG VEIHVDSVLP VPPIEFGVSP KDSDFSLPPG
1810 1820 1830 1840 1850 1860
SASGPTGSPV VKLQDALASN AGLTQSIPIL RRDHHIQRAI GLSPMSFPTA DLTLKMESAR
1870 1880 1890 1900 1910 1920
KAWENSPSLP EQSSPGGAGS GIQPPSSVGA SSGVNYSSFG GVSMPPMPVA SVAPSASMPG
1930 1940 1950 1960 1970 1980
SHLPPLYLDG HVFASQPRLV PQTIPQQQSY QQAAAAQQIP ISLHTSLQAQ AQLGLRGGLP
1990 2000 2010 2020 2030 2040
VSQSQEIFSS LQPFRSQVYM HPSLSPPSTM ILSGGTALKP PYSAFPGMQP LEMVKPQSGS
2050 2060 2070 2080 2090 2100
PYQPMSGNQA LVYEGQLSQA AGLGASQMLD SQLPQLTMPL PRYGSGQQPL ILPQSIQLPP
2110 2120 2130 2140 2150 2160
GQSLSVGAPR RIPPPGSQPP VLNTSREPSQ MEMKGFHFAD SKQNVPSGGP VPSPQTYRPS
2170 2180 2190 2200 2210 2220
SASPSGKPSG SAVNMGSVQG HYVQQAKQRV DEKPSLGAVK LQEAPSAASQ MKRTGAIKPR
AVKVEESKA
Protein Neighborhood
Domains & Features
9 N-termini - 5 C-termini - 3 Cleavages - 0 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
Q5JSZ5-1-unknown | MSDRLG... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
Q5JSZ5-1-unknown | MSDRLG... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt86098 | |||
Q5JSZ5-416-unknown | SMSSAD... | 416 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC14560 | |||
Q5JSZ5-416-unknown | SMSSAD... | 416 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt152270 | |||
Q5JSZ5-1442-unknown | EKPVRP... | 1442 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC6517 | |||
Q5JSZ5-1561-unknown | GFIEVL... | 1561 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC12471 | |||
Q5JSZ5-1561-unknown | GFIEVL... | 1561 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt156737 | |||
Q5JSZ5-1777-unknown | SVLPVP... | 1777 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt165835 | |||
Q5JSZ5-1777- | SVLPVP... | 1777 | Subtiligase Based Positive Selection | Wells | apoptotic_DB_Doxo | 23264352 | |||
Q5JSZ5-1777- | SVLPVP... | 1777 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_bortezomib | 23264352 | |||
Q5JSZ5-1777- | SVLPVP... | 1777 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
Q5JSZ5-1777- | SVLPVP... | 1777 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1s_bort | 23264352 | |||
Q5JSZ5-1777- | SVLPVP... | 1777 | Subtiligase Based Positive Selection | Wells | apoptosis_U266_bortezomib_induced | 23264352 | |||
Q5JSZ5-1904-unknown | MPPMPV... | 1904 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt86095 | |||
Q5JSZ5-1904-unknown | MPPMPV... | 1904 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt86096 | |||
Q5JSZ5-1904-unknown | MPPMPV... | 1904 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt86097 | |||
Q5JSZ5-1904-unknown | MPPMPV... | 1904 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt100398 | |||
Q5JSZ5-1930-unknown | GHVFAS... | 1930 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt175617 | |||
Q5JSZ5-1930-unknown | GHVFAS... | 1930 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt175618 | |||
Q5JSZ5-1930-unknown | GHVFAS... | 1930 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt175619 | |||
Q5JSZ5-1930-unknown | GHVFAS... | 1930 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt175616 | |||
Q5JSZ5-1930- | GHVFAS... | 1930 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1s_bort | 23264352 | |||
Q5JSZ5-1930- | GHVFAS... | 1930 | Subtiligase Based Positive Selection | Wells | apoptotic_RPMI_Dox | 23264352 |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...RQRQLS | 415 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC14560 | |||
...RQRQLS | 415 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt135680 | |||
...PGGFGE | 1441 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC6517 | |||
...QFDLNY | 1535 | COFRADIC | Gevaert K. | Van Damme P et al.: Complementary positional proteomics for screening substrates... | 20526345, | |||
...QFDLNY | 1535 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt143971 | |||
...SMVGEG | 1560 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC12471 | |||
...SMVGEG | 1560 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt140225 | |||
...EESKA | 2229 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
...EESKA | 2229 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt81713 | |||
...EESKA | 2229 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt81714 | |||
...EESKA | 2229 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt81716 |
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
GRAM_HUMAN | 415 | RQLS.|.SMSS | inferred from experiment | unknown | MEROPS | Bovenschen N | de Poot SA et al.:Human and mouse granzyme M disp... (S01.139) | 21564021, |
CATL1_HUMAN | 1441 | GFGE.|.EKPV | inferred from experiment | unknown | MEROPS | Schilling O | Biniossek ML et al.:Proteomic identification of pro... (C01.060) | 21967108, |
GRAB_HUMAN | 1560 | VGEG.|.GFIE | inferred from experiment | unknown | MEROPS | Gevaert K | Van Damme P et al.:Complementary positional proteo... (M14.017) | 20526345, |
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|