Q9UIG0: Tyrosine-protein kinase BAZ1B
Protein names | - Tyrosine-protein kinase BAZ1B - 2.7.10.2 - Bromodomain adjacent to zinc finger domain protein 1B - Williams syndrome transcription factor - Williams-Beuren syndrome chromosomal region 10 protein - Williams-Beuren syndrome chromosomal region 9 protein - hWALp2 |
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Gene names | BAZ1B |
Organism | Homo sapiens |
Protease Family | |
Protease ID | |
Chromosome location | |
UniProt ID | Q9UIG0 |
5
N-termini
3
C-termini
2
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MAPLLGRKPF PLVKPLPGEE PLFTIPHTQE AFRTREEYEA RLERYSERIW TCKSTGSSQL
70 80 90 100 110 120
THKEAWEEEQ EVAELLKEEF PAWYEKLVLE MVHHNTASLE KLVDTAWLEI MTKYAVGEEC
130 140 150 160 170 180
DFEVGKEKML KVKIVKIHPL EKVDEEATEK KSDGACDSPS SDKENSSQIA QDHQKKETVV
190 200 210 220 230 240
KEDEGRRESI NDRARRSPRK LPTSLKKGER KWAPPKFLPH KYDVKLQNED KIISNVPADS
250 260 270 280 290 300
LIRTERPPNK EIVRYFIRHN ALRAGTGENA PWVVEDELVK KYSLPSKFSD FLLDPYKYMT
310 320 330 340 350 360
LNPSTKRKNT GSPDRKPSKK SKTDNSSLSS PLNPKLWCHV HLKKSLSGSP LKVKNSKNSK
370 380 390 400 410 420
SPEEHLEEMM KMMSPNKLHT NFHIPKKGPP AKKPGKHSDK PLKAKGRSKG ILNGQKSTGN
430 440 450 460 470 480
SKSPKKGLKT PKTKMKQMTL LDMAKGTQKM TRAPRNSGGT PRTSSKPHKH LPPAALHLIA
490 500 510 520 530 540
YYKENKDRED KRSALSCVIS KTARLLSSED RARLPEELRS LVQKRYELLE HKKRWASMSE
550 560 570 580 590 600
EQRKEYLKKK REELKKKLKE KAKERREKEM LERLEKQKRY EDQELTGKNL PAFRLVDTPE
610 620 630 640 650 660
GLPNTLFGDV AMVVEFLSCY SGLLLPDAQY PITAVSLMEA LSADKGGFLY LNRVLVILLQ
670 680 690 700 710 720
TLLQDEIAED YGELGMKLSE IPLTLHSVSE LVRLCLRRSD VQEESEGSDT DDNKDSAAFE
730 740 750 760 770 780
DNEVQDEFLE KLETSEFFEL TSEEKLQILT ALCHRILMTY SVQDHMETRQ QMSAELWKER
790 800 810 820 830 840
LAVLKEENDK KRAEKQKRKE MEAKNKENGK VENGLGKTDR KKEIVKFEPQ VDTEAEDMIS
850 860 870 880 890 900
AVKSRRLLAI QAKKEREIQE REMKVKLERQ AEEERIRKHK AAAEKAFQEG IAKAKLVMRR
910 920 930 940 950 960
TPIGTDRNHN RYWLFSDEVP GLFIEKGWVH DSIDYRFNHH CKDHTVSGDE DYCPRSKKAN
970 980 990 1000 1010 1020
LGKNASMNTQ HGTATEVAVE TTTPKQGQNL WFLCDSQKEL DELLNCLHPQ GIRESQLKER
1030 1040 1050 1060 1070 1080
LEKRYQDIIH SIHLARKPNL GLKSCDGNQE LLNFLRSDLI EVATRLQKGG LGYVEETSEF
1090 1100 1110 1120 1130 1140
EARVISLEKL KDFGECVIAL QASVIKKFLQ GFMAPKQKRR KLQSEDSAKT EEVDEEKKMV
1150 1160 1170 1180 1190 1200
EEAKVASALE KWKTAIREAQ TFSRMHVLLG MLDACIKWDM SAENARCKVC RKKGEDDKLI
1210 1220 1230 1240 1250 1260
LCDECNKAFH LFCLRPALYE VPDGEWQCPA CQPATARRNS RGRNYTEESA SEDSEDDESD
1270 1280 1290 1300 1310 1320
EEEEEEEEEE EEEDYEVAGL RLRPRKTIRG KHSVIPPAAR SGRRPGKKPH STRRSQPKAP
1330 1340 1350 1360 1370 1380
PVDDAEVDEL VLQTKRSSRR QSLELQKCEE ILHKIVKYRF SWPFREPVTR DEAEDYYDVI
1390 1400 1410 1420 1430 1440
THPMDFQTVQ NKCSCGSYRS VQEFLTDMKQ VFTNAEVYNC RGSHVLSCMV KTEQCLVALL
1450 1460 1470 1480
HKHLPGHPYV RRKRKKFPDR LAEDEGDSEP EAVGQSRGRR QKK
Isoforms
- Isoform 2 of Tyrosine-protein kinase BAZ1BSequence View
10 20 30 40 50 60
MAPLLGRKPF PLVKPLPGEE PLFTIPHTQE AFRTREEYEA RLERYSERIW TCKSTGSSQL
70 80 90 100 110 120
THKEAWEEEQ EVAELLKEEF PAWYEKLVLE MVHHNTASLE KLVDTAWLEI MTKYAVGEEC
130 140 150 160 170 180
DFEVGKEKML KVKIVKIHPL EKVDEEATEK KSDGACDSPS SDKENSSQIA QDHQKKETVV
190 200 210 220 230 240
KEDEGRRESI NDRARRSPRK LPTSLKKGER KWAPPKFLPH KYDVKLQNED KIISNVPADS
250 260 270 280 290 300
LIRTERPPNK EIVRYFIRHN ALRAGTGENA PWVVEDELVK KYSLPSKFSD FLLDPYKYMT
310 320 330 340 350 360
LNPSTKRKNT GSPDRKPSKK SKTDNSSLSS PLNPKLWCHV HLKKSLSGSP LKVKNSKNSK
370 380 390 400 410 420
SPEEHLEEMM KMMSPNKLHT NFHIPKKGPP AKKPGKHSDK PLKAKGRSKG ILNGQKSTGN
430 440 450 460 470 480
SKSPKKGLKT PKTKMKQMTL LDMAKGTQKM TRAPRNSGGT PRTSSKPHKH LPPAALHLIA
490 500 510 520 530 540
YYKENKDRED KRSALSCVIS KTARLLSSED RARLPEELRS LVQKRYELLE HKKRWASMSE
550 560 570 580 590 600
EQRKEYLKKK REELKKKLKE KAKERREKEM LERLEKQKRY EDQELTGKNL PAFRLVDTPE
610 620 630 640 650 660
GLPNTLFGDV AMVVEFLSCY SGLLLPDAQY PITAVSLMEA LSADKGGFLY LNRVLVILLQ
670 680 690 700 710 720
TLLQDEIAED YGELGMKLSE IPLTLHSVSE LVRLCLRRSD VQEESEGSDT DDNKDSAAFE
730 740 750 760 770 780
DNEVQDEFLE KLETSEFFEL TSEEKLQILT ALCHRILMTY SVQDHMETRQ QMSAELWKER
790 800 810 820 830 840
LAVLKEENDK KRAEKQKRKE MEAKNKENGK VENGLGKTDR KKEIVKFEPQ VDTEAEDMIS
850 860 870 880 890 900
AVKSRRLLAI QAKKEREIQE REMKVKLERQ AEEERIRKHK AAAEKAFQEG IAKAKLVMRR
910 920 930 940 950 960
TPIGTDRNHN RYWLFSDEVP GLFIEKGWVH DSIDYRFNHH CKDHTVSGDE DYCPRSKKAN
970 980 990 1000 1010 1020
LGKNASMNTQ HGTATEVAVE TTTPKQGQNL WFLCDSQKEL DELLNCLHPQ GIRESQLKER
1030 1040 1050 1060 1070 1080
LEKRYQDIIH SIHLARKPNL GLKSCDGNQE LLNFLRSDLI EVATRLQKGG LGYVEETSEF
1090 1100 1110 1120 1130 1140
EARVISLEKL KDFGECVIAL QASVIKKFLQ GFMAPKQKRR KLQSEDSAKT EEVDEEKKMV
1150 1160 1170 1180 1190 1200
EEAKVASALE KWKTAIREAQ TFSRMHVLLG MLDACIKWDM SAENARCKVC RKKGEDDKLI
1210 1220 1230 1240 1250 1260
LCDECNKAFH LFCLRPALYE VPDGEWQCPA CQPATARRNS RGRNYTEESA SEDSEDDESD
1270 1280 1290 1300 1310 1320
EEEEEEEEEE EEEDYEVAGL RLRPRKTIRG KHSVIPPAAR SGRRPGKKPH STRRSQPKAP
1330 1340 1350 1360 1370 1380
PVDDAEVDEL VLQTKRSSRR QSLELQKCEE ILHKIVKYRF SWPFREPVTR DEAEDYYDVI
1390 1400 1410 1420 1430 1440
THPMDFQTVQ NKCSCGSYRS VQEFLTDMKQ VFTNAEVYNC RGSHVLSCMV KTEQCLVALL
1450 1460 1470 1480
HKHLPGHPYV RRKRKKFPDR LAEDEGDSEP EAVGQSRGRR QKK
Protein Neighborhood
Domains & Features
5 N-termini - 3 C-termini - 2 Cleavages - 0 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
Q9UIG0-1-unknown | MAPLLG... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
Q9UIG0-1-unknown | MAPLLG... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt68236 | |||
Q9UIG0-716-unknown | SAAFED... | 716 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt175703 | |||
Q9UIG0-716- | SAAFED... | 716 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1s_bort | 23264352 | |||
Q9UIG0-716- | SAAFED... | 716 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1SDBJurkat_Mix | 23264352 | |||
Q9UIG0-833-unknown | TEAEDM... | 833 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC13532 | |||
Q9UIG0-833-unknown | TEAEDM... | 833 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt156603 | |||
Q9UIG0-1329-unknown | ELVLQT... | 1329 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC13534 | |||
Q9UIG0-1329-unknown | ELVLQT... | 1329 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt157936 |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...EPQVDT | 832 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC13532 | |||
...EPQVDT | 832 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt140088 | |||
...DAEVDE | 1328 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC13534 | |||
...DAEVDE | 1328 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt141433 | |||
...RRQKK | 1483 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
...RRQKK | 1483 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt63854 |
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
GRAB_HUMAN | 832 | QVDT.|.TEAE | inferred from experiment | unknown | MEROPS | Gevaert K | Van Damme P et al.:Complementary positional proteo... (M14.017) | 20526345, |
GRAB_HUMAN | 1328 | EVDE.|.ELVL | inferred from experiment | unknown | MEROPS | Gevaert K | Van Damme P et al.:Complementary positional proteo... (M14.017) | 20526345, |
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
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