B2RPK0: Putative high mobility group protein B1-like 1

General Information

Protein names	- Putative high mobility group protein B1-like 1 - High mobility group protein B1 pseudogene 1 - Putative high mobility group protein 1-like 1 - HMG-1L1
Gene names	HMGB1P1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	B2RPK0

6 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MGKGDPKKPR GKMSSYAFFV QTCREEHKKK HSDASVNFSE FSNKCSERWK TMSAKEKGKF
        70         80         90        100        110        120
EDMAKADKTH YERQMKTYIP PKGETKKKFK DPNAPKRPPS AFFLFCSEYH PKIKGEHPGL
       130        140        150        160        170        180
SIGDVAKKLG EMWNNTAADD KQPGEKKAAK LKEKYEKDIA AYQAKGKPEA AKKGVVKAEK
       190        200        210
SKKKKEEEED EEDEEDEEEE DEEDEEDDDD E

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

6 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
B2RPK0-1-acetylation	MGKGDP...	1	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
B2RPK0-1-acetylation	MGKGDP...	1	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
B2RPK0-2-	GKGDPK...	2			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
B2RPK0-2-	GKGDPK...	2			Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
B2RPK0-2-	GKGDPK...	2			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
B2RPK0-2-	GKGDPK...	2			Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
B2RPK0-2-unknown	GKGDPK...	2		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
B2RPK0-2-unknown	GKGDPK...	2		inferred from similarity	unknown	UniProtKB		inferred from uniprot (by similarity)
B2RPK0-2-unknown	GKGDPK...	2			COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
B2RPK0-2-unknown	GKGDPK...	2			COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
B2RPK0-17-unknown	AFFVQT...	17		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC10625
B2RPK0-52-	MSAKEK...	52			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
B2RPK0-77-	TYIPPK...	77			Subtiligase Based Positive Selection		Wells	apopotic_Jurkat_FasL	23264352

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...KMSSYA	16	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC10625
	...DDDDE	211	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAB_HUMAN	16	SSYA.\|.AFFV	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Complementary positional proteo... (M14.017)	20526345,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)