TopFIND 4.0

Q86YT6: E3 ubiquitin-protein ligase MIB1

General Information

Protein names
- E3 ubiquitin-protein ligase MIB1
- 2.3.2.27
- DAPK-interacting protein 1
- DIP-1
- Mind bomb homolog 1
- RING-type E3 ubiquitin transferase MIB1 {ECO:0000305}
- Zinc finger ZZ type with ankyrin repeat domain protein 2
Gene names MIB1
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q86YT6

2

N-termini

2

C-termini

1

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MSNSRNNRVM VEGVGARVVR GPDWKWGKQD GGEGHVGTVR SFESPEEVVV VWDNGTAANY 
        70         80         90        100        110        120 
RCSGAYDLRI LDSAPTGIKH DGTMCDTCRQ QPIIGIRWKC AECTNYDLCT VCYHGDKHHL 
       130        140        150        160        170        180 
RHRFYRITTP GSERVLLESR RKSKKITARG IFAGARVVRG VDWQWEDQDG GNGRRGKVTE 
       190        200        210        220        230        240 
IQDWSASSPH SAAYVLWDNG AKNLYRVGFE GMSDLKCVQD AKGGSFYRDH CPVLGEQNGN 
       250        260        270        280        290        300 
RNPGGLQIGD LVNIDLDLEI VQSLQHGHGG WTDGMFETLT TTGTVCGIDE DHDIVVQYPS 
       310        320        330        340        350        360 
GNRWTFNPAV LTKANIVRSG DAAQGAEGGT SQFQVGDLVQ VCYDLERIKL LQRGHGEWAE 
       370        380        390        400        410        420 
AMLPTLGKVG RVQQIYSDSD LKVEVCGTSW TYNPAAVSKV ASAGSAISNA SGERLSQLLK 
       430        440        450        460        470        480 
KLFETQESGD LNEELVKAAA NGDVAKVEDL LKRPDVDVNG QCAGHTAMQA ASQNGHVDIL 
       490        500        510        520        530        540 
KLLLKQNVDV EAEDKDGDRA VHHAAFGDEG AVIEVLHRGS ADLNARNKRR QTPLHIAVNK 
       550        560        570        580        590        600 
GHLQVVKTLL DFGCHPSLQD SEGDTPLHDA ISKKRDDILA VLLEAGADVT ITNNNGFNAL 
       610        620        630        640        650        660 
HHAALRGNPS AMRVLLSKLP RPWIVDEKKD DGYTALHLAA LNNHVEVAEL LVHQGNANLD 
       670        680        690        700        710        720 
IQNVNQQTAL HLAVERQHTQ IVRLLVRAGA KLDIQDKDGD TPLHEALRHH TLSQLRQLQD 
       730        740        750        760        770        780 
MQDVGKVDAA WEPSKNTLIM GLGTQGAEKK SAASIACFLA ANGADLSIRN KKGQSPLDLC 
       790        800        810        820        830        840 
PDPNLCKALA KCHKEKVSGQ VGSRSPSMIS NDSETLEECM VCSDMKRDTL FGPCGHIATC 
       850        860        870        880        890        900 
SLCSPRVKKC LICKEQVQSR TKIEECVVCS DKKAAVLFQP CGHMCACENC ANLMKKCVQC 
       910        920        930        940        950        960 
RAVVERRVPF IMCCGGKSSE DATDDISSGN IPVLQKDKDN TNVNADVQKL QQQLQDIKEQ 
       970        980        990       1000    
TMCPVCLDRL KNMIFLCGHG TCQLCGDRMS ECPICRKAIE RRILLY

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

2 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q86YT6-1-unknown MSNSRN... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q86YT6-813-unknown SETLEE... 813 inferred from cleavage unknown TopFIND Inferred from cleavage TC12777

C-termini

Cleavages

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)