Q9UPN7: Serine/threonine-protein phosphatase 6 regulatory subunit 1
Protein names | - Serine/threonine-protein phosphatase 6 regulatory subunit 1 - SAPS domain family member 1 |
---|---|
Gene names | PPP6R1 |
Organism | Homo sapiens |
Protease Family | |
Protease ID | |
Chromosome location | |
UniProt ID | Q9UPN7 |
7
N-termini
3
C-termini
1
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MFWKFDLHTS SHLDTLLERE DLSLPELLDE EDVLQECKVV NRKLLDFLLQ PPHLQAMVAW
70 80 90 100 110 120
VTQEPPDSGE ERLRYKYPSV ACEILTSDVP QINDALGADE SLLNRLYGFL QSTGSLNPLL
130 140 150 160 170 180
ASFFSKVMGI LINRKTDQLV SFLRKKDDFV DLLLQHIGTS AIMDLLLRLL TCVERPQLRQ
190 200 210 220 230 240
DVVNWLNEEK IVQRLIEQIH PSKDENQHSN ASQSLCDIIR LSREQMIQVQ DSPEPDQLLA
250 260 270 280 290 300
TLEKQETIEQ LLSNMFEGEQ SQSVIVSGIQ VLLTLLEPRR PRSESVTVNS FFSSVDGQLE
310 320 330 340 350 360
LLAQGALEST VSSVGALHAL RPRLSCFHQL LLEPPKLEPL QMTWGMLAPP LGNTRLHVVK
370 380 390 400 410 420
LLASALSAND AALTHELLAL DVPNTMLDLF FHYVFNNFLH AQVEGCVSTM LSLGPPPDSS
430 440 450 460 470 480
PETPIQNPVV KHLLQQCRLV ERILTSWEEN DRVQCAGGPR KGYMGHLTRV AGALVQNTEK
490 500 510 520 530 540
GPNAEQLRQL LKELPSEQQE QWEAFVSGPL AETNKKNMVD LVNTHHLHSS SDDEDDRLKE
550 560 570 580 590 600
FNFPEEAVLQ QAFMDFQMQR MTSAFIDHFG FNDEEFGEQE ESVNAPFDKT ANITFSLNAD
610 620 630 640 650 660
DENPNANLLE ICYKDRIQQF DDDEEEEDEE EAQGSGESDG EDGAWQGSQL ARGARLGQPP
670 680 690 700 710 720
GVRSGGSTDS EDEEEEDEEE EEDEEGIGCA ARGGATPLSY PSPGPQPPGP SWTATFDPVP
730 740 750 760 770 780
TDAPTSPRVS GEEELHTGPP APQGPLSVPQ GLPTQSLASP PARDALQLRS QDPTPPSAPQ
790 800 810 820 830 840
EATEGSKVTE PSAPCQALVS IGDLQATFHG IRSAPSSSDS ATRDPSTSVP ASGAHQPPQT
850 860 870 880
TEGEKSPEPL GLPQSQSAQA LTPPPIPNGS APEGPASPGS Q
Isoforms
Sequence View
Protein Neighborhood
Domains & Features
7 N-termini - 3 C-termini - 1 Cleavages - 0 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
Q9UPN7-1-unknown | MFWKFD... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
Q9UPN7-58- | VAWVTQ... | 58 | Subtiligase Based Positive Selection | Wells | apoptosis_U266_bortezomib_induced | 23264352 | |||
Q9UPN7-60- | WVTQEP... | 60 | Subtiligase Based Positive Selection | Wells | apoptosis_U266_bortezomib_induced | 23264352 | |||
Q9UPN7-297- | GQLELL... | 297 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_bortezomib | 23264352 | |||
Q9UPN7-297- | GQLELL... | 297 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_Etoposide | 23264352 | |||
Q9UPN7-297- | GQLELL... | 297 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
Q9UPN7-297- | GQLELL... | 297 | Subtiligase Based Positive Selection | Wells | apoptosis_U266_bortezomib_induced | 23264352 | |||
Q9UPN7-359-unknown | VKLLAS... | 359 | unknown | Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage... | 18722006 | ||||
Q9UPN7-552- | AFMDFQ... | 552 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_bortezomib | 23264352 | |||
Q9UPN7-598-unknown | NADDEN... | 598 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC15143 |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...LLQHIG | 157 | inferred from electronic annotation | unknown | Ensembl | inferred from ensembl protein ENSP00000466332 | |||
...ITFSLN | 597 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC15143 | |||
...SPGSQ | 881 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
GRAM_HUMAN | 597 | FSLN.|.NADD | inferred from experiment | unknown | MEROPS | Bovenschen N | de Poot SA et al.:Human and mouse granzyme M disp... (S01.139) | 21564021, |
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
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