Q9UKM9: RNA-binding protein Raly

General Information

Protein names	- RNA-binding protein Raly - Autoantigen p542 - Heterogeneous nuclear ribonucleoprotein C-like 2 - hnRNP core protein C-like 2 - hnRNP associated with lethal yellow protein homolog
Gene names	RALY
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9UKM9

36 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MSLKLQASNV TNKNDPKSIN SRVFIGNLNT ALVKKSDVET IFSKYGRVAG CSVHKGYAFV
        70         80         90        100        110        120
QYSNERHARA AVLGENGRVL AGQTLDINMA GEPKPDRPKG LKRAASAIYS GYIFDYDYYR
       130        140        150        160        170        180
DDFYDRLFDY RGRLSPVPVP RAVPVKRPRV TVPLVRRVKT NVPVKLFARS TAVTTSSAKI
       190        200        210        220        230        240
KLKSSELQAI KTELTQIKSN IDALLSRLEQ IAAEQKANPD GKKKGDGGGA GGGGGGGGSG
       250        260        270        280        290        300
GGGSGGGGGG GSSRPPAPQE NTTSEAGLPQ GEARTRDDGD EEGLLTHSEE ELEHSQDTDA

DDGALQ

Isoforms

- Isoform 1 of RNA-binding protein Raly

Sequence View

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Evidence Codes:

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Protein Neighborhood

Domains & Features

36 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q9UKM9-1-unknown	MSLKLQ...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt86942
Q9UKM9-2-unknown	MSLKLQ...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9UKM9-2-Acetylation	SLKLQA...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9UKM9-2-Acetylation	SLKLQA...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
Q9UKM9-2-Acetylation	SLKLQA...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
Q9UKM9-2-Acetylation	SLKLQA...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt111540
Q9UKM9-5-unknown	LQASNV...	5		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt169946
Q9UKM9-5-	LQASNV...	5			Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
Q9UKM9-7-	ASNVTN...	7			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
Q9UKM9-7-	ASNVTN...	7			Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
Q9UKM9-7-unknown	ASNVTN...	7		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt167072
Q9UKM9-70-	AAVLGE...	70			Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
Q9UKM9-70-unknown	AAVLGE...	70		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt178299
Q9UKM9-142-	AVPVKR...	142			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q9UKM9-142-unknown	AVPVKR...	142		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt172254
Q9UKM9-167-unknown	FARSTA...	167		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC15106
Q9UKM9-167-unknown	FARSTA...	167		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt144763
Q9UKM9-170-unknown	STAVTT...	170		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt164932
Q9UKM9-170-	STAVTT...	170			Subtiligase Based Positive Selection		Wells	DB_Untreated	23264352
Q9UKM9-232-unknown	GGGGGG...	232		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt172250
Q9UKM9-232-	GGGGGG...	232			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q9UKM9-232-	GGGGGG...	232			Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q9UKM9-233-	GGGGGG...	233			Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q9UKM9-233-unknown	GGGGGG...	233		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt174619
Q9UKM9-241-	GGGSGG...	241			Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
Q9UKM9-241-	GGGSGG...	241			Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q9UKM9-241-unknown	GGGSGG...	241		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt165462
Q9UKM9-245-	GGGGGG...	245			Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
Q9UKM9-245-	GGGGGG...	245			Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q9UKM9-245-unknown	GGGGGG...	245		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt165460
Q9UKM9-246-	GGGGGG...	246			Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q9UKM9-246-unknown	GGGGGG...	246		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt174621
Q9UKM9-247-	GGGGGS...	247			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
Q9UKM9-247-	GGGGGS...	247			Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q9UKM9-247-	GGGGGS...	247			Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
Q9UKM9-247-unknown	GGGGGS...	247		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt167068
Q9UKM9-248-	GGGGSS...	248			Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q9UKM9-248-unknown	GGGGSS...	248		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt174617
Q9UKM9-251-	GSSRPP...	251			Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
Q9UKM9-251-	GSSRPP...	251			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q9UKM9-251-	GSSRPP...	251			Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q9UKM9-251-unknown	GSSRPP...	251		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt165464
Q9UKM9-252-	SSRPPA...	252			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
Q9UKM9-252-	SSRPPA...	252			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q9UKM9-252-	SSRPPA...	252			Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q9UKM9-252-	SSRPPA...	252			Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
Q9UKM9-252-unknown	SSRPPA...	252		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt167070
Q9UKM9-253-	SRPPAP...	253			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q9UKM9-253-	SRPPAP...	253			Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q9UKM9-253-	SRPPAP...	253			Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
Q9UKM9-253-unknown	SRPPAP...	253		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt172252
Q9UKM9-262-unknown	TTSEAG...	262		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt174623
Q9UKM9-262-	TTSEAG...	262			Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...VPVKLF	166	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC15106
...VPVKLF	166	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt128038
...DGALQ	306	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...DGALQ	306	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt82560

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAM_HUMAN	166	VKLF.\|.FARS	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)