Q6PL24: Protein TMED8

General Information

Protein names	- Protein TMED8
Gene names	TMED8
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q6PL24

3 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MSDLQAAEGP GSWSPTARPG SAGGVGDCQG VEGSQAAASE NEDLENKDTS LLASATDPEP
        70         80         90        100        110        120
CSSPHRPQMV SPVSKDATED LRKATGPLEA QALVKQDLLP ADQAQVLNEM AKYQVPQRSG
       130        140        150        160        170        180
DIVMIQSEHT GAIDVLSADL ESADLLGDHR KVSPPLMAPP CIWTFAKVKE FKSKLGKEKN
       190        200        210        220        230        240
SRLVVKRGEV VTIRVPTHPE GKRVCWEFAT DDYDIGFGVY FDWTPVTSTD ITVQVSDSSD
       250        260        270        280        290        300
DEDEEEEEEE EIEEPVPAGD VERGSRSSLR GRYGEVMPVY RRDSHRDVQA GSHDYPGEGI
       310        320
YLLKFDNSYS LLRNKTLYFH IYYTS

Isoforms

Sequence View

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Evidence Names:

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Protein Neighborhood

Domains & Features

3 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q6PL24-1-unknown	MSDLQA...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q6PL24-132-	AIDVLS...	132		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
Q6PL24-132-	AIDVLS...	132		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q6PL24-132-	AIDVLS...	132		Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
Q6PL24-137-unknown	SADLES...	137	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC14630

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...AIDVLS	136	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC14630
	...IYYTS	325	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAM_HUMAN	136	DVLS.\|.SADL	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)