Q14011: Cold-inducible RNA-binding protein

General Information

Protein names	- Cold-inducible RNA-binding protein - A18 hnRNP - Glycine-rich RNA-binding protein CIRP
Gene names	CIRBP
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q14011

3 N-termini

7 C-termini

1 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Cold-inducible RNA-binding protein - Isoform 3 of Cold-inducible RNA-binding protein

Sequence View

        10         20         30         40         50         60
MASDEGKLFV GGLSFDTNEQ SLEQVFSKYG QISEVVVVKD RETQRSRGFG FVTFENIDDA
        70         80         90        100        110        120
KDAMMAMNGK SVDGRQIRVD QAGKSSDNRS RGYRGGSAGG RGFFRGGRGR GRGFSRGGGD
       130        140        150        160        170
RGYGGNRFES RSGGYGGSRD YYSSRSQSGG YSDRSSGGSY RDSYDSYATH NE         10         20         30         40         50         60
MASDEGKLFV GGLSFDTNEQ SLEQVFSKYG QISEVVVVKD RETQRSRGFG FVTFENIDDA
        70         80         90        100        110        120
KDAMMAMNGK SVDGRQIRVD QAGKSSDNRS RGYRGGSAGG RGFFRGGRGR GRGFSRGGGD
       130        140        150        160        170
RGYGGNRFES RSGGYGGSRD YYSSRSQSGG YSDRSSGGSY RDSYDSYATH NE

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(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

3 N-termini - 7 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name	Publications (PMID)
Q14011-1-unknown	MASDEG...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q14011-65-unknown	MAMNGK...	65	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC14476
Q14011-132-unknown	SGGYGG...	132		unknown		Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
...KYGQIS	32	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000468016
...AKDAMM	64	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC14476
...AMNGKS	70	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000466238
...RGFFRG	105	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000465338
...SSGGSY	159	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000466712
...ATHNE	172		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...ATHNE	172		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,
...ATHNE	172	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
...ATHNE	172		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...ATHNE	172		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAM_HUMAN	64	DAMM.\|.MAMN	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)