Q14331: Protein FRG1

General Information

Protein names	- Protein FRG1 - FSHD region gene 1 protein
Gene names	FRG1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q14331

3 N-termini

4 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAEYSYVKST KLVLKGTKTK SKKKKSKDKK RKREEDEETQ LDIVGIWWTV TNFGEISGTI
        70         80         90        100        110        120
AIEMDKGTYI HALDNGLFTL GAPHKEVDEG PSPPEQFTAV KLSDSRIALK SGYGKYLGIN
       130        140        150        160        170        180
SDGLVVGRSD AIGPREQWEP VFQNGKMALL ASNSCFIRCN EAGDIEAKSK TAGEEEMIKI
       190        200        210        220        230        240
RSCAERETKK KDDIPEEDKG NVKQCEINYV KKFQSFQDHK LKISKEDSKI LKKARKDGFL
       250
HETLLDRRAK LKADRYCK

Isoforms

Sequence View

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Evidence Codes:

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Evidence Names:

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Protein Neighborhood

Domains & Features

3 N-termini - 4 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q14331-1-unknown	MAEYSY...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q14331-15-unknown	KGTKTK...	15	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC14487
Q14331-64-unknown	MDKGTY...	64	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000457797
Q14331-64-unknown	MDKGTY...	64	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000435943

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...TKLVLK	14	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC14487
...EEMIKI	179	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000457797
...EEMIKI	179	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000435943
...EDSKIL	230	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000455022
...EDSKIL	230	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000435067
...DRYCK	258	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAM_HUMAN	14	LVLK.\|.KGTK	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)