Q9UIK4: Death-associated protein kinase 2
Protein names | - Death-associated protein kinase 2 - DAP kinase 2 - 2.7.11.1 {ECO:0000269|PubMed:10376525, ECO:0000269|PubMed:26047703} - DAP-kinase-related protein 1 - DRP-1 |
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Gene names | DAPK2 |
Organism | Homo sapiens |
Protease Family | |
Protease ID | |
Chromosome location | |
UniProt ID | Q9UIK4 |
2
N-termini
2
C-termini
1
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MFQASMRSPN MEPFKQQKVE DFYDIGEELG SGQFAIVKKC REKSTGLEYA AKFIKKRQSR
70 80 90 100 110 120
ASRRGVSREE IEREVSILRQ VLHHNVITLH DVYENRTDVV LILELVSGGE LFDFLAQKES
130 140 150 160 170 180
LSEEEATSFI KQILDGVNYL HTKKIAHFDL KPENIMLLDK NIPIPHIKLI DFGLAHEIED
190 200 210 220 230 240
GVEFKNIFGT PEFVAPEIVN YEPLGLEADM WSIGVITYIL LSGASPFLGD TKQETLANIT
250 260 270 280 290 300
AVSYDFDEEF FSQTSELAKD FIRKLLVKET RKRLTIQEAL RHPWITPVDN QQAMVRRESV
310 320 330 340 350 360
VNLENFRKQY VRRRWKLSFS IVSLCNHLTR SLMKKVHLRP DEDLRNCESD TEEDIARRKA
370
LHPRRRSSTS
Isoforms
- Isoform 2 of Death-associated protein kinase 2Sequence View
10 20 30 40 50 60
MFQASMRSPN MEPFKQQKVE DFYDIGEELG SGQFAIVKKC REKSTGLEYA AKFIKKRQSR
70 80 90 100 110 120
ASRRGVSREE IEREVSILRQ VLHHNVITLH DVYENRTDVV LILELVSGGE LFDFLAQKES
130 140 150 160 170 180
LSEEEATSFI KQILDGVNYL HTKKIAHFDL KPENIMLLDK NIPIPHIKLI DFGLAHEIED
190 200 210 220 230 240
GVEFKNIFGT PEFVAPEIVN YEPLGLEADM WSIGVITYIL LSGASPFLGD TKQETLANIT
250 260 270 280 290 300
AVSYDFDEEF FSQTSELAKD FIRKLLVKET RKRLTIQEAL RHPWITPVDN QQAMVRRESV
310 320 330 340 350 360
VNLENFRKQY VRRRWKLSFS IVSLCNHLTR SLMKKVHLRP DEDLRNCESD TEEDIARRKA
370
LHPRRRSSTS
Protein Neighborhood
Domains & Features
2 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
Q9UIK4-1-unknown | MFQASM... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
Q9UIK4-1-unknown | MFQASM... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt72345 | |||
Q9UIK4-52-unknown | KFIKKR... | 52 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC15104 | |||
Q9UIK4-52-unknown | KFIKKR... | 52 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt139305 |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...LEYAAK | 51 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC15104 | |||
...LEYAAK | 51 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt122380 | |||
...RSSTS | 370 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
GRAM_HUMAN | 51 | YAAK.|.KFIK | inferred from experiment | unknown | MEROPS | Bovenschen N | de Poot SA et al.:Human and mouse granzyme M disp... (S01.139) | 21564021, |
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
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