Q13823: Nucleolar GTP-binding protein 2

General Information

Protein names	- Nucleolar GTP-binding protein 2 - Autoantigen NGP-1
Gene names	GNL2
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q13823

4 N-termini

4 C-termini

2 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MVKPKYKGRS TINPSKASTN PDRVQGAGGQ NMRDRATIRR LNMYRQKERR NSRGKIIKPL
        70         80         90        100        110        120
QYQSTVASGT VARVEPNIKW FGNTRVIKQS SLQKFQEEMD TVMKDPYKVV MKQSKLPMSL
       130        140        150        160        170        180
LHDRIRPHNL KVHILDTESF ETTFGPKSQR KRPNLFASDM QSLIENAEMS TESYDQGKDR
       190        200        210        220        230        240
DLVTEDTGVR NEAQEEIYKK GQSKRIWGEL YKVIDSSDVV VQVLDARDPM GTRSPHIETY
       250        260        270        280        290        300
LKKEKPWKHL IFVLNKCDLV PTWATKRWVA VLSQDYPTLA FHASLTNPFG KGAFIQLLRQ
       310        320        330        340        350        360
FGKLHTDKKQ ISVGFIGYPN VGKSSVINTL RSKKVCNVAP IAGETKVWQY ITLMRRIFLI
       370        380        390        400        410        420
DCPGVVYPSE DSETDIVLKG VVQVEKIKSP EDHIGAVLER AKPEYISKTY KIDSWENAED
       430        440        450        460        470        480
FLEKLAFRTG KLLKGGEPDL QTVGKMVLND WQRGRIPFFV KPPNAEPLVA PQLLPSSSLE
       490        500        510        520        530        540
VVPEAAQNNP GEEVTETAGE GSESIIKEET EENSHCDANT EMQQILTRVR QNFGKINVVP
       550        560        570        580        590        600
QFSGDDLVPV EVSDLEEELE SFSDEEEEEQ EQQRDDAEES SSEPEEENVG NDTKAVIKAL
       610        620        630        640        650        660
DEKIAKYQKF LDKAKAKKFS AVRISKGLSE KIFAKPEEQR KTLEEDVDDR APSKKGKKRK
       670        680        690        700        710        720
AQREEEQEHS NKAPRALTSK ERRRAVRQQR PKKVGVRYYE THNVKNRNRN KKKTNDSEGQ
       730
KHKRKKFRQK Q

Isoforms

Sequence View

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Protease Assignment Confidence:

Evidence Names:

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Protein Neighborhood

Domains & Features

4 N-termini - 4 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q13823-1-Acetylation	MVKPKY...	1	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q13823-2-unknown	VKPKYK...	2			COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
Q13823-2-unknown	VKPKYK...	2			COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
Q13823-61-unknown	QYQSTV...	61		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC14466
Q13823-94-unknown	KFQEEM...	94		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC14467

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...IIKPLQ	60	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC14466
...QSSLQK	93	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC14467
...LKGVVQ	382	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000441288
...FRQKQ	731	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAM_HUMAN	60	KPLQ.\|.QYQS	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,
GRAM_HUMAN	93	SLQK.\|.KFQE	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)