O94966: Ubiquitin carboxyl-terminal hydrolase 19
Protein names | - Ubiquitin carboxyl-terminal hydrolase 19 - 3.4.19.12 - Deubiquitinating enzyme 19 - Ubiquitin thioesterase 19 - Ubiquitin-specific-processing protease 19 - Zinc finger MYND domain-containing protein 9 |
---|---|
Gene names | USP19 |
Organism | Homo sapiens |
Protease Family | |
Protease ID | C19.024 |
Chromosome location | |
UniProt ID | O94966 |
9
N-termini
2
C-termini
1
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MSGGASATGP RRGPPGLEDT TSKKKQKDRA NQESKDGDPR KETGSRYVAQ AGLEPLASGD
70 80 90 100 110 120
PSASASHAAG ITGSRHRTRL FFPSSSGSAS TPQEEQTKEG ACEDPHDLLA TPTPELLLDW
130 140 150 160 170 180
RQSAEEVIVK LRVGVGPLQL EDVDAAFTDT DCVVRFAGGQ QWGGVFYAEI KSSCAKVQTR
190 200 210 220 230 240
KGSLLHLTLP KKVPMLTWPS LLVEADEQLC IPPLNSQTCL LGSEENLAPL AGEKAVPPGN
250 260 270 280 290 300
DPVSPAMVRS RNPGKDDCAK EEMAVAADAA TLVDEPESMV NLAFVKNDSY EKGPDSVVVH
310 320 330 340 350 360
VYVKEICRDT SRVLFREQDF TLIFQTRDGN FLRLHPGCGP HTTFRWQVKL RNLIEPEQCT
370 380 390 400 410 420
FCFTASRIDI CLRKRQSQRW GGLEAPAARV GGAKVAVPTG PTPLDSTPPG GAPHPLTGQE
430 440 450 460 470 480
EARAVEKDKS KARSEDTGLD SVATRTPMEH VTPKPETHLA SPKPTCMVPP MPHSPVSGDS
490 500 510 520 530 540
VEEEEEEEKK VCLPGFTGLV NLGNTCFMNS VIQSLSNTRE LRDFFHDRSF EAEINYNNPL
550 560 570 580 590 600
GTGGRLAIGF AVLLRALWKG THHAFQPSKL KAIVASKASQ FTGYAQHDAQ EFMAFLLDGL
610 620 630 640 650 660
HEDLNRIQNK PYTETVDSDG RPDEVVAEEA WQRHKMRNDS FIVDLFQGQY KSKLVCPVCA
670 680 690 700 710 720
KVSITFDPFL YLPVPLPQKQ KVLPVFYFAR EPHSKPIKFL VSVSKENSTA SEVLDSLSQS
730 740 750 760 770 780
VHVKPENLRL AEVIKNRFHR VFLPSHSLDT VSPSDTLLCF ELLSSELAKE RVVVLEVQQR
790 800 810 820 830 840
PQVPSVPISK CAACQRKQQS EDEKLKRCTR CYRVGYCNQL CQKTHWPDHK GLCRPENIGY
850 860 870 880 890 900
PFLVSVPASR LTYARLAQLL EGYARYSVSV FQPPFQPGRM ALESQSPGCT TLLSTGSLEA
910 920 930 940 950 960
GDSERDPIQP PELQLVTPMA EGDTGLPRVW AAPDRGPVPS TSGISSEMLA SGPIEVGSLP
970 980 990 1000 1010 1020
AGERVSRPEA AVPGYQHPSE AMNAHTPQFF IYKIDSSNRE QRLEDKGDTP LELGDDCSLA
1030 1040 1050 1060 1070 1080
LVWRNNERLQ EFVLVASKEL ECAEDPGSAG EAARAGHFTL DQCLNLFTRP EVLAPEEAWY
1090 1100 1110 1120 1130 1140
CPQCKQHREA SKQLLLWRLP NVLIVQLKRF SFRSFIWRDK INDLVEFPVR NLDLSKFCIG
1150 1160 1170 1180 1190 1200
QKEEQLPSYD LYAVINHYGG MIGGHYTACA RLPNDRSSQR SDVGWRLFDD STVTTVDESQ
1210 1220 1230 1240 1250 1260
VVTRYAYVLF YRRRNSPVER PPRAGHSEHH PDLGPAAEAA ASQASRIWQE LEAEEEPVPE
1270 1280 1290 1300 1310
GSGPLGPWGP QDWVGPLPRG PTTPDEGCLR YFVLGTVAAL VALVLNVFYP LVSQSRWR
Isoforms
- Isoform 2 of Ubiquitin carboxyl-terminal hydrolase 19 - Isoform 3 of Ubiquitin carboxyl-terminal hydrolase 19 - Isoform 4 of Ubiquitin carboxyl-terminal hydrolase 19 - Isoform 5 of Ubiquitin carboxyl-terminal hydrolase 19 - Isoform 6 of Ubiquitin carboxyl-terminal hydrolase 19 - Isoform 7 of Ubiquitin carboxyl-terminal hydrolase 19Sequence View
10 20 30 40 50 60
MSGGASATGP RRGPPGLEDT TSKKKQKDRA NQESKDGDPR KETGSRYVAQ AGLEPLASGD
70 80 90 100 110 120
PSASASHAAG ITGSRHRTRL FFPSSSGSAS TPQEEQTKEG ACEDPHDLLA TPTPELLLDW
130 140 150 160 170 180
RQSAEEVIVK LRVGVGPLQL EDVDAAFTDT DCVVRFAGGQ QWGGVFYAEI KSSCAKVQTR
190 200 210 220 230 240
KGSLLHLTLP KKVPMLTWPS LLVEADEQLC IPPLNSQTCL LGSEENLAPL AGEKAVPPGN
250 260 270 280 290 300
DPVSPAMVRS RNPGKDDCAK EEMAVAADAA TLVDEPESMV NLAFVKNDSY EKGPDSVVVH
310 320 330 340 350 360
VYVKEICRDT SRVLFREQDF TLIFQTRDGN FLRLHPGCGP HTTFRWQVKL RNLIEPEQCT
370 380 390 400 410 420
FCFTASRIDI CLRKRQSQRW GGLEAPAARV GGAKVAVPTG PTPLDSTPPG GAPHPLTGQE
430 440 450 460 470 480
EARAVEKDKS KARSEDTGLD SVATRTPMEH VTPKPETHLA SPKPTCMVPP MPHSPVSGDS
490 500 510 520 530 540
VEEEEEEEKK VCLPGFTGLV NLGNTCFMNS VIQSLSNTRE LRDFFHDRSF EAEINYNNPL
550 560 570 580 590 600
GTGGRLAIGF AVLLRALWKG THHAFQPSKL KAIVASKASQ FTGYAQHDAQ EFMAFLLDGL
610 620 630 640 650 660
HEDLNRIQNK PYTETVDSDG RPDEVVAEEA WQRHKMRNDS FIVDLFQGQY KSKLVCPVCA
670 680 690 700 710 720
KVSITFDPFL YLPVPLPQKQ KVLPVFYFAR EPHSKPIKFL VSVSKENSTA SEVLDSLSQS
730 740 750 760 770 780
VHVKPENLRL AEVIKNRFHR VFLPSHSLDT VSPSDTLLCF ELLSSELAKE RVVVLEVQQR
790 800 810 820 830 840
PQVPSVPISK CAACQRKQQS EDEKLKRCTR CYRVGYCNQL CQKTHWPDHK GLCRPENIGY
850 860 870 880 890 900
PFLVSVPASR LTYARLAQLL EGYARYSVSV FQPPFQPGRM ALESQSPGCT TLLSTGSLEA
910 920 930 940 950 960
GDSERDPIQP PELQLVTPMA EGDTGLPRVW AAPDRGPVPS TSGISSEMLA SGPIEVGSLP
970 980 990 1000 1010 1020
AGERVSRPEA AVPGYQHPSE AMNAHTPQFF IYKIDSSNRE QRLEDKGDTP LELGDDCSLA
1030 1040 1050 1060 1070 1080
LVWRNNERLQ EFVLVASKEL ECAEDPGSAG EAARAGHFTL DQCLNLFTRP EVLAPEEAWY
1090 1100 1110 1120 1130 1140
CPQCKQHREA SKQLLLWRLP NVLIVQLKRF SFRSFIWRDK INDLVEFPVR NLDLSKFCIG
1150 1160 1170 1180 1190 1200
QKEEQLPSYD LYAVINHYGG MIGGHYTACA RLPNDRSSQR SDVGWRLFDD STVTTVDESQ
1210 1220 1230 1240 1250 1260
VVTRYAYVLF YRRRNSPVER PPRAGHSEHH PDLGPAAEAA ASQASRIWQE LEAEEEPVPE
1270 1280 1290 1300 1310
GSGPLGPWGP QDWVGPLPRG PTTPDEGCLR YFVLGTVAAL VALVLNVFYP LVSQSRWR
10 20 30 40 50 60
MSGGASATGP RRGPPGLEDT TSKKKQKDRA NQESKDGDPR KETGSRYVAQ AGLEPLASGD
70 80 90 100 110 120
PSASASHAAG ITGSRHRTRL FFPSSSGSAS TPQEEQTKEG ACEDPHDLLA TPTPELLLDW
130 140 150 160 170 180
RQSAEEVIVK LRVGVGPLQL EDVDAAFTDT DCVVRFAGGQ QWGGVFYAEI KSSCAKVQTR
190 200 210 220 230 240
KGSLLHLTLP KKVPMLTWPS LLVEADEQLC IPPLNSQTCL LGSEENLAPL AGEKAVPPGN
250 260 270 280 290 300
DPVSPAMVRS RNPGKDDCAK EEMAVAADAA TLVDEPESMV NLAFVKNDSY EKGPDSVVVH
310 320 330 340 350 360
VYVKEICRDT SRVLFREQDF TLIFQTRDGN FLRLHPGCGP HTTFRWQVKL RNLIEPEQCT
370 380 390 400 410 420
FCFTASRIDI CLRKRQSQRW GGLEAPAARV GGAKVAVPTG PTPLDSTPPG GAPHPLTGQE
430 440 450 460 470 480
EARAVEKDKS KARSEDTGLD SVATRTPMEH VTPKPETHLA SPKPTCMVPP MPHSPVSGDS
490 500 510 520 530 540
VEEEEEEEKK VCLPGFTGLV NLGNTCFMNS VIQSLSNTRE LRDFFHDRSF EAEINYNNPL
550 560 570 580 590 600
GTGGRLAIGF AVLLRALWKG THHAFQPSKL KAIVASKASQ FTGYAQHDAQ EFMAFLLDGL
610 620 630 640 650 660
HEDLNRIQNK PYTETVDSDG RPDEVVAEEA WQRHKMRNDS FIVDLFQGQY KSKLVCPVCA
670 680 690 700 710 720
KVSITFDPFL YLPVPLPQKQ KVLPVFYFAR EPHSKPIKFL VSVSKENSTA SEVLDSLSQS
730 740 750 760 770 780
VHVKPENLRL AEVIKNRFHR VFLPSHSLDT VSPSDTLLCF ELLSSELAKE RVVVLEVQQR
790 800 810 820 830 840
PQVPSVPISK CAACQRKQQS EDEKLKRCTR CYRVGYCNQL CQKTHWPDHK GLCRPENIGY
850 860 870 880 890 900
PFLVSVPASR LTYARLAQLL EGYARYSVSV FQPPFQPGRM ALESQSPGCT TLLSTGSLEA
910 920 930 940 950 960
GDSERDPIQP PELQLVTPMA EGDTGLPRVW AAPDRGPVPS TSGISSEMLA SGPIEVGSLP
970 980 990 1000 1010 1020
AGERVSRPEA AVPGYQHPSE AMNAHTPQFF IYKIDSSNRE QRLEDKGDTP LELGDDCSLA
1030 1040 1050 1060 1070 1080
LVWRNNERLQ EFVLVASKEL ECAEDPGSAG EAARAGHFTL DQCLNLFTRP EVLAPEEAWY
1090 1100 1110 1120 1130 1140
CPQCKQHREA SKQLLLWRLP NVLIVQLKRF SFRSFIWRDK INDLVEFPVR NLDLSKFCIG
1150 1160 1170 1180 1190 1200
QKEEQLPSYD LYAVINHYGG MIGGHYTACA RLPNDRSSQR SDVGWRLFDD STVTTVDESQ
1210 1220 1230 1240 1250 1260
VVTRYAYVLF YRRRNSPVER PPRAGHSEHH PDLGPAAEAA ASQASRIWQE LEAEEEPVPE
1270 1280 1290 1300 1310
GSGPLGPWGP QDWVGPLPRG PTTPDEGCLR YFVLGTVAAL VALVLNVFYP LVSQSRWR
10 20 30 40 50 60
MSGGASATGP RRGPPGLEDT TSKKKQKDRA NQESKDGDPR KETGSRYVAQ AGLEPLASGD
70 80 90 100 110 120
PSASASHAAG ITGSRHRTRL FFPSSSGSAS TPQEEQTKEG ACEDPHDLLA TPTPELLLDW
130 140 150 160 170 180
RQSAEEVIVK LRVGVGPLQL EDVDAAFTDT DCVVRFAGGQ QWGGVFYAEI KSSCAKVQTR
190 200 210 220 230 240
KGSLLHLTLP KKVPMLTWPS LLVEADEQLC IPPLNSQTCL LGSEENLAPL AGEKAVPPGN
250 260 270 280 290 300
DPVSPAMVRS RNPGKDDCAK EEMAVAADAA TLVDEPESMV NLAFVKNDSY EKGPDSVVVH
310 320 330 340 350 360
VYVKEICRDT SRVLFREQDF TLIFQTRDGN FLRLHPGCGP HTTFRWQVKL RNLIEPEQCT
370 380 390 400 410 420
FCFTASRIDI CLRKRQSQRW GGLEAPAARV GGAKVAVPTG PTPLDSTPPG GAPHPLTGQE
430 440 450 460 470 480
EARAVEKDKS KARSEDTGLD SVATRTPMEH VTPKPETHLA SPKPTCMVPP MPHSPVSGDS
490 500 510 520 530 540
VEEEEEEEKK VCLPGFTGLV NLGNTCFMNS VIQSLSNTRE LRDFFHDRSF EAEINYNNPL
550 560 570 580 590 600
GTGGRLAIGF AVLLRALWKG THHAFQPSKL KAIVASKASQ FTGYAQHDAQ EFMAFLLDGL
610 620 630 640 650 660
HEDLNRIQNK PYTETVDSDG RPDEVVAEEA WQRHKMRNDS FIVDLFQGQY KSKLVCPVCA
670 680 690 700 710 720
KVSITFDPFL YLPVPLPQKQ KVLPVFYFAR EPHSKPIKFL VSVSKENSTA SEVLDSLSQS
730 740 750 760 770 780
VHVKPENLRL AEVIKNRFHR VFLPSHSLDT VSPSDTLLCF ELLSSELAKE RVVVLEVQQR
790 800 810 820 830 840
PQVPSVPISK CAACQRKQQS EDEKLKRCTR CYRVGYCNQL CQKTHWPDHK GLCRPENIGY
850 860 870 880 890 900
PFLVSVPASR LTYARLAQLL EGYARYSVSV FQPPFQPGRM ALESQSPGCT TLLSTGSLEA
910 920 930 940 950 960
GDSERDPIQP PELQLVTPMA EGDTGLPRVW AAPDRGPVPS TSGISSEMLA SGPIEVGSLP
970 980 990 1000 1010 1020
AGERVSRPEA AVPGYQHPSE AMNAHTPQFF IYKIDSSNRE QRLEDKGDTP LELGDDCSLA
1030 1040 1050 1060 1070 1080
LVWRNNERLQ EFVLVASKEL ECAEDPGSAG EAARAGHFTL DQCLNLFTRP EVLAPEEAWY
1090 1100 1110 1120 1130 1140
CPQCKQHREA SKQLLLWRLP NVLIVQLKRF SFRSFIWRDK INDLVEFPVR NLDLSKFCIG
1150 1160 1170 1180 1190 1200
QKEEQLPSYD LYAVINHYGG MIGGHYTACA RLPNDRSSQR SDVGWRLFDD STVTTVDESQ
1210 1220 1230 1240 1250 1260
VVTRYAYVLF YRRRNSPVER PPRAGHSEHH PDLGPAAEAA ASQASRIWQE LEAEEEPVPE
1270 1280 1290 1300 1310
GSGPLGPWGP QDWVGPLPRG PTTPDEGCLR YFVLGTVAAL VALVLNVFYP LVSQSRWR
10 20 30 40 50 60
MSGGASATGP RRGPPGLEDT TSKKKQKDRA NQESKDGDPR KETGSRYVAQ AGLEPLASGD
70 80 90 100 110 120
PSASASHAAG ITGSRHRTRL FFPSSSGSAS TPQEEQTKEG ACEDPHDLLA TPTPELLLDW
130 140 150 160 170 180
RQSAEEVIVK LRVGVGPLQL EDVDAAFTDT DCVVRFAGGQ QWGGVFYAEI KSSCAKVQTR
190 200 210 220 230 240
KGSLLHLTLP KKVPMLTWPS LLVEADEQLC IPPLNSQTCL LGSEENLAPL AGEKAVPPGN
250 260 270 280 290 300
DPVSPAMVRS RNPGKDDCAK EEMAVAADAA TLVDEPESMV NLAFVKNDSY EKGPDSVVVH
310 320 330 340 350 360
VYVKEICRDT SRVLFREQDF TLIFQTRDGN FLRLHPGCGP HTTFRWQVKL RNLIEPEQCT
370 380 390 400 410 420
FCFTASRIDI CLRKRQSQRW GGLEAPAARV GGAKVAVPTG PTPLDSTPPG GAPHPLTGQE
430 440 450 460 470 480
EARAVEKDKS KARSEDTGLD SVATRTPMEH VTPKPETHLA SPKPTCMVPP MPHSPVSGDS
490 500 510 520 530 540
VEEEEEEEKK VCLPGFTGLV NLGNTCFMNS VIQSLSNTRE LRDFFHDRSF EAEINYNNPL
550 560 570 580 590 600
GTGGRLAIGF AVLLRALWKG THHAFQPSKL KAIVASKASQ FTGYAQHDAQ EFMAFLLDGL
610 620 630 640 650 660
HEDLNRIQNK PYTETVDSDG RPDEVVAEEA WQRHKMRNDS FIVDLFQGQY KSKLVCPVCA
670 680 690 700 710 720
KVSITFDPFL YLPVPLPQKQ KVLPVFYFAR EPHSKPIKFL VSVSKENSTA SEVLDSLSQS
730 740 750 760 770 780
VHVKPENLRL AEVIKNRFHR VFLPSHSLDT VSPSDTLLCF ELLSSELAKE RVVVLEVQQR
790 800 810 820 830 840
PQVPSVPISK CAACQRKQQS EDEKLKRCTR CYRVGYCNQL CQKTHWPDHK GLCRPENIGY
850 860 870 880 890 900
PFLVSVPASR LTYARLAQLL EGYARYSVSV FQPPFQPGRM ALESQSPGCT TLLSTGSLEA
910 920 930 940 950 960
GDSERDPIQP PELQLVTPMA EGDTGLPRVW AAPDRGPVPS TSGISSEMLA SGPIEVGSLP
970 980 990 1000 1010 1020
AGERVSRPEA AVPGYQHPSE AMNAHTPQFF IYKIDSSNRE QRLEDKGDTP LELGDDCSLA
1030 1040 1050 1060 1070 1080
LVWRNNERLQ EFVLVASKEL ECAEDPGSAG EAARAGHFTL DQCLNLFTRP EVLAPEEAWY
1090 1100 1110 1120 1130 1140
CPQCKQHREA SKQLLLWRLP NVLIVQLKRF SFRSFIWRDK INDLVEFPVR NLDLSKFCIG
1150 1160 1170 1180 1190 1200
QKEEQLPSYD LYAVINHYGG MIGGHYTACA RLPNDRSSQR SDVGWRLFDD STVTTVDESQ
1210 1220 1230 1240 1250 1260
VVTRYAYVLF YRRRNSPVER PPRAGHSEHH PDLGPAAEAA ASQASRIWQE LEAEEEPVPE
1270 1280 1290 1300 1310
GSGPLGPWGP QDWVGPLPRG PTTPDEGCLR YFVLGTVAAL VALVLNVFYP LVSQSRWR
10 20 30 40 50 60
MSGGASATGP RRGPPGLEDT TSKKKQKDRA NQESKDGDPR KETGSRYVAQ AGLEPLASGD
70 80 90 100 110 120
PSASASHAAG ITGSRHRTRL FFPSSSGSAS TPQEEQTKEG ACEDPHDLLA TPTPELLLDW
130 140 150 160 170 180
RQSAEEVIVK LRVGVGPLQL EDVDAAFTDT DCVVRFAGGQ QWGGVFYAEI KSSCAKVQTR
190 200 210 220 230 240
KGSLLHLTLP KKVPMLTWPS LLVEADEQLC IPPLNSQTCL LGSEENLAPL AGEKAVPPGN
250 260 270 280 290 300
DPVSPAMVRS RNPGKDDCAK EEMAVAADAA TLVDEPESMV NLAFVKNDSY EKGPDSVVVH
310 320 330 340 350 360
VYVKEICRDT SRVLFREQDF TLIFQTRDGN FLRLHPGCGP HTTFRWQVKL RNLIEPEQCT
370 380 390 400 410 420
FCFTASRIDI CLRKRQSQRW GGLEAPAARV GGAKVAVPTG PTPLDSTPPG GAPHPLTGQE
430 440 450 460 470 480
EARAVEKDKS KARSEDTGLD SVATRTPMEH VTPKPETHLA SPKPTCMVPP MPHSPVSGDS
490 500 510 520 530 540
VEEEEEEEKK VCLPGFTGLV NLGNTCFMNS VIQSLSNTRE LRDFFHDRSF EAEINYNNPL
550 560 570 580 590 600
GTGGRLAIGF AVLLRALWKG THHAFQPSKL KAIVASKASQ FTGYAQHDAQ EFMAFLLDGL
610 620 630 640 650 660
HEDLNRIQNK PYTETVDSDG RPDEVVAEEA WQRHKMRNDS FIVDLFQGQY KSKLVCPVCA
670 680 690 700 710 720
KVSITFDPFL YLPVPLPQKQ KVLPVFYFAR EPHSKPIKFL VSVSKENSTA SEVLDSLSQS
730 740 750 760 770 780
VHVKPENLRL AEVIKNRFHR VFLPSHSLDT VSPSDTLLCF ELLSSELAKE RVVVLEVQQR
790 800 810 820 830 840
PQVPSVPISK CAACQRKQQS EDEKLKRCTR CYRVGYCNQL CQKTHWPDHK GLCRPENIGY
850 860 870 880 890 900
PFLVSVPASR LTYARLAQLL EGYARYSVSV FQPPFQPGRM ALESQSPGCT TLLSTGSLEA
910 920 930 940 950 960
GDSERDPIQP PELQLVTPMA EGDTGLPRVW AAPDRGPVPS TSGISSEMLA SGPIEVGSLP
970 980 990 1000 1010 1020
AGERVSRPEA AVPGYQHPSE AMNAHTPQFF IYKIDSSNRE QRLEDKGDTP LELGDDCSLA
1030 1040 1050 1060 1070 1080
LVWRNNERLQ EFVLVASKEL ECAEDPGSAG EAARAGHFTL DQCLNLFTRP EVLAPEEAWY
1090 1100 1110 1120 1130 1140
CPQCKQHREA SKQLLLWRLP NVLIVQLKRF SFRSFIWRDK INDLVEFPVR NLDLSKFCIG
1150 1160 1170 1180 1190 1200
QKEEQLPSYD LYAVINHYGG MIGGHYTACA RLPNDRSSQR SDVGWRLFDD STVTTVDESQ
1210 1220 1230 1240 1250 1260
VVTRYAYVLF YRRRNSPVER PPRAGHSEHH PDLGPAAEAA ASQASRIWQE LEAEEEPVPE
1270 1280 1290 1300 1310
GSGPLGPWGP QDWVGPLPRG PTTPDEGCLR YFVLGTVAAL VALVLNVFYP LVSQSRWR
10 20 30 40 50 60
MSGGASATGP RRGPPGLEDT TSKKKQKDRA NQESKDGDPR KETGSRYVAQ AGLEPLASGD
70 80 90 100 110 120
PSASASHAAG ITGSRHRTRL FFPSSSGSAS TPQEEQTKEG ACEDPHDLLA TPTPELLLDW
130 140 150 160 170 180
RQSAEEVIVK LRVGVGPLQL EDVDAAFTDT DCVVRFAGGQ QWGGVFYAEI KSSCAKVQTR
190 200 210 220 230 240
KGSLLHLTLP KKVPMLTWPS LLVEADEQLC IPPLNSQTCL LGSEENLAPL AGEKAVPPGN
250 260 270 280 290 300
DPVSPAMVRS RNPGKDDCAK EEMAVAADAA TLVDEPESMV NLAFVKNDSY EKGPDSVVVH
310 320 330 340 350 360
VYVKEICRDT SRVLFREQDF TLIFQTRDGN FLRLHPGCGP HTTFRWQVKL RNLIEPEQCT
370 380 390 400 410 420
FCFTASRIDI CLRKRQSQRW GGLEAPAARV GGAKVAVPTG PTPLDSTPPG GAPHPLTGQE
430 440 450 460 470 480
EARAVEKDKS KARSEDTGLD SVATRTPMEH VTPKPETHLA SPKPTCMVPP MPHSPVSGDS
490 500 510 520 530 540
VEEEEEEEKK VCLPGFTGLV NLGNTCFMNS VIQSLSNTRE LRDFFHDRSF EAEINYNNPL
550 560 570 580 590 600
GTGGRLAIGF AVLLRALWKG THHAFQPSKL KAIVASKASQ FTGYAQHDAQ EFMAFLLDGL
610 620 630 640 650 660
HEDLNRIQNK PYTETVDSDG RPDEVVAEEA WQRHKMRNDS FIVDLFQGQY KSKLVCPVCA
670 680 690 700 710 720
KVSITFDPFL YLPVPLPQKQ KVLPVFYFAR EPHSKPIKFL VSVSKENSTA SEVLDSLSQS
730 740 750 760 770 780
VHVKPENLRL AEVIKNRFHR VFLPSHSLDT VSPSDTLLCF ELLSSELAKE RVVVLEVQQR
790 800 810 820 830 840
PQVPSVPISK CAACQRKQQS EDEKLKRCTR CYRVGYCNQL CQKTHWPDHK GLCRPENIGY
850 860 870 880 890 900
PFLVSVPASR LTYARLAQLL EGYARYSVSV FQPPFQPGRM ALESQSPGCT TLLSTGSLEA
910 920 930 940 950 960
GDSERDPIQP PELQLVTPMA EGDTGLPRVW AAPDRGPVPS TSGISSEMLA SGPIEVGSLP
970 980 990 1000 1010 1020
AGERVSRPEA AVPGYQHPSE AMNAHTPQFF IYKIDSSNRE QRLEDKGDTP LELGDDCSLA
1030 1040 1050 1060 1070 1080
LVWRNNERLQ EFVLVASKEL ECAEDPGSAG EAARAGHFTL DQCLNLFTRP EVLAPEEAWY
1090 1100 1110 1120 1130 1140
CPQCKQHREA SKQLLLWRLP NVLIVQLKRF SFRSFIWRDK INDLVEFPVR NLDLSKFCIG
1150 1160 1170 1180 1190 1200
QKEEQLPSYD LYAVINHYGG MIGGHYTACA RLPNDRSSQR SDVGWRLFDD STVTTVDESQ
1210 1220 1230 1240 1250 1260
VVTRYAYVLF YRRRNSPVER PPRAGHSEHH PDLGPAAEAA ASQASRIWQE LEAEEEPVPE
1270 1280 1290 1300 1310
GSGPLGPWGP QDWVGPLPRG PTTPDEGCLR YFVLGTVAAL VALVLNVFYP LVSQSRWR
Protein Neighborhood
Domains & Features
9 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
O94966-1-unknown | MSGGAS... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
O94966-1-unknown | MSGGAS... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt93649 | |||
O94966-1-unknown | MSGGAS... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt93650 | |||
O94966-1-unknown | MSGGAS... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt93651 | |||
O94966-1-unknown | MSGGAS... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt93652 | |||
O94966-1-unknown | MSGGAS... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt93653 | |||
O94966-1-unknown | MSGGAS... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt93654 | |||
O94966-2-acetylation | SGGASA... | 2 | acetylation- | COFRADIC | Gevaert K. | Van Damme P et al.: Complementary positional proteomics for screening substrates... | 20526345 | ||
O94966-2-acetylation | SGGASA... | 2 | acetylation- | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt163072 | ||
O94966-2-acetylation | SGGASA... | 2 | acetylation- | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt163073 | ||
O94966-2-acetylation | SGGASA... | 2 | acetylation- | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt163068 | ||
O94966-2-acetylation | SGGASA... | 2 | acetylation- | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt163069 | ||
O94966-2-acetylation | SGGASA... | 2 | acetylation- | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt163070 | ||
O94966-2-acetylation | SGGASA... | 2 | acetylation- | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt163071 | ||
O94966-57-unknown | ASGDPS... | 57 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC13857 | |||
O94966-57-unknown | ASGDPS... | 57 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt139651 | |||
O94966-57-unknown | ASGDPS... | 57 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt139652 | |||
O94966-57-unknown | ASGDPS... | 57 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt139654 | |||
O94966-57-unknown | ASGDPS... | 57 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt139656 | |||
O94966-57-unknown | ASGDPS... | 57 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt139657 | |||
O94966-57-unknown | ASGDPS... | 57 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt139658 | |||
O94966-396- | AVPTGP... | 396 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_bortezomib | 23264352 | |||
O94966-396- | AVPTGP... | 396 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
O94966-396- | AVPTGP... | 396 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1s_bort | 23264352 | |||
O94966-396-unknown | AVPTGP... | 396 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt167766 | |||
O94966-396-unknown | AVPTGP... | 396 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt167767 | |||
O94966-396-unknown | AVPTGP... | 396 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt167768 | |||
O94966-396-unknown | AVPTGP... | 396 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt167763 | |||
O94966-396-unknown | AVPTGP... | 396 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt167765 | |||
O94966-396-unknown | AVPTGP... | 396 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt167764 | |||
O94966-618-unknown | SDGRPD... | 618 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt176833 | |||
O94966-618-unknown | SDGRPD... | 618 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt176834 | |||
O94966-618-unknown | SDGRPD... | 618 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt176830 | |||
O94966-618-unknown | SDGRPD... | 618 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt176832 | |||
O94966-618-unknown | SDGRPD... | 618 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt176831 | |||
O94966-618- | SDGRPD... | 618 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1SDBJurkat_Mix | 23264352 | |||
O94966-620-unknown | GRPDEV... | 620 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt171873 | |||
O94966-620-unknown | GRPDEV... | 620 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt171874 | |||
O94966-620-unknown | GRPDEV... | 620 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt171870 | |||
O94966-620-unknown | GRPDEV... | 620 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt171872 | |||
O94966-620-unknown | GRPDEV... | 620 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt171871 | |||
O94966-620- | GRPDEV... | 620 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
O94966-620- | GRPDEV... | 620 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1SDBJurkat_Mix | 23264352 | |||
O94966-620- | GRPDEV... | 620 | Subtiligase Based Positive Selection | Wells | apoptosis_U266_bortezomib_induced | 23264352 |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...GLEPLA | 56 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC13857 | |||
...GLEPLA | 56 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt122746 | |||
...GLEPLA | 56 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt122747 | |||
...GLEPLA | 56 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt122749 | |||
...GLEPLA | 56 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt122751 | |||
...GLEPLA | 56 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt122752 | |||
...GLEPLA | 56 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt122753 | |||
...QSRWR | 1318 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
...QSRWR | 1318 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt89270 |
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
GRAM_HUMAN | 56 | EPLA.|.ASGD | inferred from experiment | unknown | MEROPS | Bovenschen N | de Poot SA et al.:Human and mouse granzyme M disp... (S01.139) | 21564021, |
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
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