Q5VZL5: Zinc finger MYM-type protein 4
Protein names | - Zinc finger MYM-type protein 4 - Zinc finger protein 262 |
---|---|
Gene names | ZMYM4 |
Organism | Homo sapiens |
Protease Family | |
Protease ID | |
Chromosome location | |
UniProt ID | Q5VZL5 |
8
N-termini
2
C-termini
1
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MAEREVESGP RKRFEQKSGA VFDEIVENCG GIMDTEMSED IDHNLTPTLD SMSYGMPNQT
70 80 90 100 110 120
GSENSLLDED DYFLNSGDLA GIPVVGSDNE DEQDFSSKDN LVSSIHTDDS LEVERRVTQH
130 140 150 160 170 180
ESDNENEIQI QNKLKKDFPK QFDQVSVFKS IRKDFSLVRE NSKETFSGKE KNRDLTYERE
190 200 210 220 230 240
KRLDKPHKDL DSRLKSSFFD KAANQVEETL HTHLPQTPET NFRDSSYPFA NKESIGSELG
250 260 270 280 290 300
NSFASNIRIK EEPLDDEYDK AMAPQQGLLD KIKDEPDNAQ EYSHGQQQKT QEGELKISAV
310 320 330 340 350 360
FSVSGSPLAP QLTTGFQPSL ASSGMNKMLP SVPATAVRVS CSGCKKILQK GQTAYQRKGS
370 380 390 400 410 420
TQLFCSTLCL TGYTVPPARP PPPLTKKTCS SCSKDILNPK DVISAQFENT TTSKDFCSQS
430 440 450 460 470 480
CLSTYELKKK PIVTINTNSI STKCSMCQKN AVIRHEVNYQ NVVHKLCSDA CFSKFRSANN
490 500 510 520 530 540
LTMNCCENCG GYCYSGSGQC HMLQIEGQSK KFCSSSCITA YKQKSAKITP CALCKSLRSS
550 560 570 580 590 600
AEMIENTNSL GKTELFCSVN CLSAYRVKMV TSAGVQVQCN SCKTSAIPQY HLAMSDGSIR
610 620 630 640 650 660
NFCSYSCVVA FQNLFNKPTG MNSSVVPLSQ GQVIVSIPTG STVSAGGGST SAVSPTSISS
670 680 690 700 710 720
SAAAGLQRLA AQSQHVGFAR SVVKLKCQHC NRLFATKPEL LDYKGKMFQF CGKNCSDEYK
730 740 750 760 770 780
KINNVMAMCE YCKIEKIVKE TVRFSGADKS FCSEGCKLLY KHDLAKRWGN HCKMCSYCLQ
790 800 810 820 830 840
TSPKLVQNNL GGKVEEFCCE ECMSKYTVLF YQMAKCDACK RQGKLSESLK WRGEMKHFCN
850 860 870 880 890 900
LLCILMFCNQ QSVCDPPSQN NAANISMVQA ASAGPPSLRK DSTPVIANVV SLASAPAAQP
910 920 930 940 950 960
TVNSNSVLQG AVPTVTAKII GDASTQTDAL KLPPSQPPRL LKNKALLCKP ITQTKATSCK
970 980 990 1000 1010 1020
PHTQNKECQT EDTPSQPQII VVPVPVPVFV PIPLHLYTQY APVPFGIPVP MPVPMLIPSS
1030 1040 1050 1060 1070 1080
MDSEDKVTES IEDIKEKLPT HPFEADLLEM AEMIAEDEEK KTLSQGESQT SEHELFLDTK
1090 1100 1110 1120 1130 1140
IFEKDQGSTY SGDLESEAVS TPHSWEEELN HYALKSNAVQ EADSELKQFS KGETEQDLEA
1150 1160 1170 1180 1190 1200
DFPSDSFDPL NKGQGIQARS RTRRRHRDGF PQPRRRGRKK SIVAVEPRSL IQGAFQGCSV
1210 1220 1230 1240 1250 1260
SGMTLKYMYG VNAWKNWVQW KNAKEEQGDL KCGGVEQASS SPRSDPLGST QDHALSQESS
1270 1280 1290 1300 1310 1320
EPGCRVRSIK LKEDILSCTF AELSLGLCQF IQEVRRPNGE KYDPDSILYL CLGIQQYLFE
1330 1340 1350 1360 1370 1380
NGRIDNIFTE PYSRFMIELT KLLKIWEPTI LPNGYMFSRI EEEHLWECKQ LGAYSPIVLL
1390 1400 1410 1420 1430 1440
NTLLFFNTKY FQLKNVTEHL KLSFAHVMRR TRTLKYSTKM TYLRFFPPLQ KQESEPDKLT
1450 1460 1470 1480 1490 1500
VGKRKRNEDD EVPVGVEMAE NTDNPLRCPV RLYEFYLSKC SESVKQRNDV FYLQPERSCV
1510 1520 1530 1540
PNSPMWYSTF PIDPGTLDTM LTRILMVREV HEELAKAKSE DSDVELSD
Isoforms
- Isoform 2 of Zinc finger MYM-type protein 4 - Isoform 3 of Zinc finger MYM-type protein 4 - Isoform 4 of Zinc finger MYM-type protein 4Sequence View
10 20 30 40 50 60
MAEREVESGP RKRFEQKSGA VFDEIVENCG GIMDTEMSED IDHNLTPTLD SMSYGMPNQT
70 80 90 100 110 120
GSENSLLDED DYFLNSGDLA GIPVVGSDNE DEQDFSSKDN LVSSIHTDDS LEVERRVTQH
130 140 150 160 170 180
ESDNENEIQI QNKLKKDFPK QFDQVSVFKS IRKDFSLVRE NSKETFSGKE KNRDLTYERE
190 200 210 220 230 240
KRLDKPHKDL DSRLKSSFFD KAANQVEETL HTHLPQTPET NFRDSSYPFA NKESIGSELG
250 260 270 280 290 300
NSFASNIRIK EEPLDDEYDK AMAPQQGLLD KIKDEPDNAQ EYSHGQQQKT QEGELKISAV
310 320 330 340 350 360
FSVSGSPLAP QLTTGFQPSL ASSGMNKMLP SVPATAVRVS CSGCKKILQK GQTAYQRKGS
370 380 390 400 410 420
TQLFCSTLCL TGYTVPPARP PPPLTKKTCS SCSKDILNPK DVISAQFENT TTSKDFCSQS
430 440 450 460 470 480
CLSTYELKKK PIVTINTNSI STKCSMCQKN AVIRHEVNYQ NVVHKLCSDA CFSKFRSANN
490 500 510 520 530 540
LTMNCCENCG GYCYSGSGQC HMLQIEGQSK KFCSSSCITA YKQKSAKITP CALCKSLRSS
550 560 570 580 590 600
AEMIENTNSL GKTELFCSVN CLSAYRVKMV TSAGVQVQCN SCKTSAIPQY HLAMSDGSIR
610 620 630 640 650 660
NFCSYSCVVA FQNLFNKPTG MNSSVVPLSQ GQVIVSIPTG STVSAGGGST SAVSPTSISS
670 680 690 700 710 720
SAAAGLQRLA AQSQHVGFAR SVVKLKCQHC NRLFATKPEL LDYKGKMFQF CGKNCSDEYK
730 740 750 760 770 780
KINNVMAMCE YCKIEKIVKE TVRFSGADKS FCSEGCKLLY KHDLAKRWGN HCKMCSYCLQ
790 800 810 820 830 840
TSPKLVQNNL GGKVEEFCCE ECMSKYTVLF YQMAKCDACK RQGKLSESLK WRGEMKHFCN
850 860 870 880 890 900
LLCILMFCNQ QSVCDPPSQN NAANISMVQA ASAGPPSLRK DSTPVIANVV SLASAPAAQP
910 920 930 940 950 960
TVNSNSVLQG AVPTVTAKII GDASTQTDAL KLPPSQPPRL LKNKALLCKP ITQTKATSCK
970 980 990 1000 1010 1020
PHTQNKECQT EDTPSQPQII VVPVPVPVFV PIPLHLYTQY APVPFGIPVP MPVPMLIPSS
1030 1040 1050 1060 1070 1080
MDSEDKVTES IEDIKEKLPT HPFEADLLEM AEMIAEDEEK KTLSQGESQT SEHELFLDTK
1090 1100 1110 1120 1130 1140
IFEKDQGSTY SGDLESEAVS TPHSWEEELN HYALKSNAVQ EADSELKQFS KGETEQDLEA
1150 1160 1170 1180 1190 1200
DFPSDSFDPL NKGQGIQARS RTRRRHRDGF PQPRRRGRKK SIVAVEPRSL IQGAFQGCSV
1210 1220 1230 1240 1250 1260
SGMTLKYMYG VNAWKNWVQW KNAKEEQGDL KCGGVEQASS SPRSDPLGST QDHALSQESS
1270 1280 1290 1300 1310 1320
EPGCRVRSIK LKEDILSCTF AELSLGLCQF IQEVRRPNGE KYDPDSILYL CLGIQQYLFE
1330 1340 1350 1360 1370 1380
NGRIDNIFTE PYSRFMIELT KLLKIWEPTI LPNGYMFSRI EEEHLWECKQ LGAYSPIVLL
1390 1400 1410 1420 1430 1440
NTLLFFNTKY FQLKNVTEHL KLSFAHVMRR TRTLKYSTKM TYLRFFPPLQ KQESEPDKLT
1450 1460 1470 1480 1490 1500
VGKRKRNEDD EVPVGVEMAE NTDNPLRCPV RLYEFYLSKC SESVKQRNDV FYLQPERSCV
1510 1520 1530 1540
PNSPMWYSTF PIDPGTLDTM LTRILMVREV HEELAKAKSE DSDVELSD
10 20 30 40 50 60
MAEREVESGP RKRFEQKSGA VFDEIVENCG GIMDTEMSED IDHNLTPTLD SMSYGMPNQT
70 80 90 100 110 120
GSENSLLDED DYFLNSGDLA GIPVVGSDNE DEQDFSSKDN LVSSIHTDDS LEVERRVTQH
130 140 150 160 170 180
ESDNENEIQI QNKLKKDFPK QFDQVSVFKS IRKDFSLVRE NSKETFSGKE KNRDLTYERE
190 200 210 220 230 240
KRLDKPHKDL DSRLKSSFFD KAANQVEETL HTHLPQTPET NFRDSSYPFA NKESIGSELG
250 260 270 280 290 300
NSFASNIRIK EEPLDDEYDK AMAPQQGLLD KIKDEPDNAQ EYSHGQQQKT QEGELKISAV
310 320 330 340 350 360
FSVSGSPLAP QLTTGFQPSL ASSGMNKMLP SVPATAVRVS CSGCKKILQK GQTAYQRKGS
370 380 390 400 410 420
TQLFCSTLCL TGYTVPPARP PPPLTKKTCS SCSKDILNPK DVISAQFENT TTSKDFCSQS
430 440 450 460 470 480
CLSTYELKKK PIVTINTNSI STKCSMCQKN AVIRHEVNYQ NVVHKLCSDA CFSKFRSANN
490 500 510 520 530 540
LTMNCCENCG GYCYSGSGQC HMLQIEGQSK KFCSSSCITA YKQKSAKITP CALCKSLRSS
550 560 570 580 590 600
AEMIENTNSL GKTELFCSVN CLSAYRVKMV TSAGVQVQCN SCKTSAIPQY HLAMSDGSIR
610 620 630 640 650 660
NFCSYSCVVA FQNLFNKPTG MNSSVVPLSQ GQVIVSIPTG STVSAGGGST SAVSPTSISS
670 680 690 700 710 720
SAAAGLQRLA AQSQHVGFAR SVVKLKCQHC NRLFATKPEL LDYKGKMFQF CGKNCSDEYK
730 740 750 760 770 780
KINNVMAMCE YCKIEKIVKE TVRFSGADKS FCSEGCKLLY KHDLAKRWGN HCKMCSYCLQ
790 800 810 820 830 840
TSPKLVQNNL GGKVEEFCCE ECMSKYTVLF YQMAKCDACK RQGKLSESLK WRGEMKHFCN
850 860 870 880 890 900
LLCILMFCNQ QSVCDPPSQN NAANISMVQA ASAGPPSLRK DSTPVIANVV SLASAPAAQP
910 920 930 940 950 960
TVNSNSVLQG AVPTVTAKII GDASTQTDAL KLPPSQPPRL LKNKALLCKP ITQTKATSCK
970 980 990 1000 1010 1020
PHTQNKECQT EDTPSQPQII VVPVPVPVFV PIPLHLYTQY APVPFGIPVP MPVPMLIPSS
1030 1040 1050 1060 1070 1080
MDSEDKVTES IEDIKEKLPT HPFEADLLEM AEMIAEDEEK KTLSQGESQT SEHELFLDTK
1090 1100 1110 1120 1130 1140
IFEKDQGSTY SGDLESEAVS TPHSWEEELN HYALKSNAVQ EADSELKQFS KGETEQDLEA
1150 1160 1170 1180 1190 1200
DFPSDSFDPL NKGQGIQARS RTRRRHRDGF PQPRRRGRKK SIVAVEPRSL IQGAFQGCSV
1210 1220 1230 1240 1250 1260
SGMTLKYMYG VNAWKNWVQW KNAKEEQGDL KCGGVEQASS SPRSDPLGST QDHALSQESS
1270 1280 1290 1300 1310 1320
EPGCRVRSIK LKEDILSCTF AELSLGLCQF IQEVRRPNGE KYDPDSILYL CLGIQQYLFE
1330 1340 1350 1360 1370 1380
NGRIDNIFTE PYSRFMIELT KLLKIWEPTI LPNGYMFSRI EEEHLWECKQ LGAYSPIVLL
1390 1400 1410 1420 1430 1440
NTLLFFNTKY FQLKNVTEHL KLSFAHVMRR TRTLKYSTKM TYLRFFPPLQ KQESEPDKLT
1450 1460 1470 1480 1490 1500
VGKRKRNEDD EVPVGVEMAE NTDNPLRCPV RLYEFYLSKC SESVKQRNDV FYLQPERSCV
1510 1520 1530 1540
PNSPMWYSTF PIDPGTLDTM LTRILMVREV HEELAKAKSE DSDVELSD
10 20 30 40 50 60
MAEREVESGP RKRFEQKSGA VFDEIVENCG GIMDTEMSED IDHNLTPTLD SMSYGMPNQT
70 80 90 100 110 120
GSENSLLDED DYFLNSGDLA GIPVVGSDNE DEQDFSSKDN LVSSIHTDDS LEVERRVTQH
130 140 150 160 170 180
ESDNENEIQI QNKLKKDFPK QFDQVSVFKS IRKDFSLVRE NSKETFSGKE KNRDLTYERE
190 200 210 220 230 240
KRLDKPHKDL DSRLKSSFFD KAANQVEETL HTHLPQTPET NFRDSSYPFA NKESIGSELG
250 260 270 280 290 300
NSFASNIRIK EEPLDDEYDK AMAPQQGLLD KIKDEPDNAQ EYSHGQQQKT QEGELKISAV
310 320 330 340 350 360
FSVSGSPLAP QLTTGFQPSL ASSGMNKMLP SVPATAVRVS CSGCKKILQK GQTAYQRKGS
370 380 390 400 410 420
TQLFCSTLCL TGYTVPPARP PPPLTKKTCS SCSKDILNPK DVISAQFENT TTSKDFCSQS
430 440 450 460 470 480
CLSTYELKKK PIVTINTNSI STKCSMCQKN AVIRHEVNYQ NVVHKLCSDA CFSKFRSANN
490 500 510 520 530 540
LTMNCCENCG GYCYSGSGQC HMLQIEGQSK KFCSSSCITA YKQKSAKITP CALCKSLRSS
550 560 570 580 590 600
AEMIENTNSL GKTELFCSVN CLSAYRVKMV TSAGVQVQCN SCKTSAIPQY HLAMSDGSIR
610 620 630 640 650 660
NFCSYSCVVA FQNLFNKPTG MNSSVVPLSQ GQVIVSIPTG STVSAGGGST SAVSPTSISS
670 680 690 700 710 720
SAAAGLQRLA AQSQHVGFAR SVVKLKCQHC NRLFATKPEL LDYKGKMFQF CGKNCSDEYK
730 740 750 760 770 780
KINNVMAMCE YCKIEKIVKE TVRFSGADKS FCSEGCKLLY KHDLAKRWGN HCKMCSYCLQ
790 800 810 820 830 840
TSPKLVQNNL GGKVEEFCCE ECMSKYTVLF YQMAKCDACK RQGKLSESLK WRGEMKHFCN
850 860 870 880 890 900
LLCILMFCNQ QSVCDPPSQN NAANISMVQA ASAGPPSLRK DSTPVIANVV SLASAPAAQP
910 920 930 940 950 960
TVNSNSVLQG AVPTVTAKII GDASTQTDAL KLPPSQPPRL LKNKALLCKP ITQTKATSCK
970 980 990 1000 1010 1020
PHTQNKECQT EDTPSQPQII VVPVPVPVFV PIPLHLYTQY APVPFGIPVP MPVPMLIPSS
1030 1040 1050 1060 1070 1080
MDSEDKVTES IEDIKEKLPT HPFEADLLEM AEMIAEDEEK KTLSQGESQT SEHELFLDTK
1090 1100 1110 1120 1130 1140
IFEKDQGSTY SGDLESEAVS TPHSWEEELN HYALKSNAVQ EADSELKQFS KGETEQDLEA
1150 1160 1170 1180 1190 1200
DFPSDSFDPL NKGQGIQARS RTRRRHRDGF PQPRRRGRKK SIVAVEPRSL IQGAFQGCSV
1210 1220 1230 1240 1250 1260
SGMTLKYMYG VNAWKNWVQW KNAKEEQGDL KCGGVEQASS SPRSDPLGST QDHALSQESS
1270 1280 1290 1300 1310 1320
EPGCRVRSIK LKEDILSCTF AELSLGLCQF IQEVRRPNGE KYDPDSILYL CLGIQQYLFE
1330 1340 1350 1360 1370 1380
NGRIDNIFTE PYSRFMIELT KLLKIWEPTI LPNGYMFSRI EEEHLWECKQ LGAYSPIVLL
1390 1400 1410 1420 1430 1440
NTLLFFNTKY FQLKNVTEHL KLSFAHVMRR TRTLKYSTKM TYLRFFPPLQ KQESEPDKLT
1450 1460 1470 1480 1490 1500
VGKRKRNEDD EVPVGVEMAE NTDNPLRCPV RLYEFYLSKC SESVKQRNDV FYLQPERSCV
1510 1520 1530 1540
PNSPMWYSTF PIDPGTLDTM LTRILMVREV HEELAKAKSE DSDVELSD
Protein Neighborhood
Domains & Features
8 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
Q5VZL5-1-unknown | MAEREV... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt95209 | |||
Q5VZL5-2-unknown | MAEREV... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
Q5VZL5-2-Acetylation | AEREVE... | 2 | acetylation- | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | ||
Q5VZL5-2-Acetylation | AEREVE... | 2 | acetylation- | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt111346 | ||
Q5VZL5-33-unknown | MDTEMS... | 33 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt95211 | |||
Q5VZL5-33-unknown | MDTEMS... | 33 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt108936 | |||
Q5VZL5-325-unknown | MNKMLP... | 325 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt95210 | |||
Q5VZL5-325-unknown | MNKMLP... | 325 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt108878 | |||
Q5VZL5-325-unknown | MNKMLP... | 325 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt108879 | |||
Q5VZL5-929-unknown | ALKLPP... | 929 | unknown | Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage... | 18722006 | ||||
Q5VZL5-929-unknown | ALKLPP... | 929 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt162338 | |||
Q5VZL5-929-unknown | ALKLPP... | 929 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt162339 | |||
Q5VZL5-929-unknown | ALKLPP... | 929 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt162337 | |||
Q5VZL5-929- | ALKLPP... | 929 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_Etoposide | 23264352 | |||
Q5VZL5-1039-unknown | PTHPFE... | 1039 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC14586 | |||
Q5VZL5-1039-unknown | PTHPFE... | 1039 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt155997 | |||
Q5VZL5-1039-unknown | PTHPFE... | 1039 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt157053 | |||
Q5VZL5-1039-unknown | PTHPFE... | 1039 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt157166 |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...IKEKLP | 1038 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC14586 | |||
...IKEKLP | 1038 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt139456 | |||
...IKEKLP | 1038 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt140547 | |||
...IKEKLP | 1038 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt140667 | |||
...VELSD | 1548 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
...VELSD | 1548 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt90828 | |||
...VELSD | 1548 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt90827 | |||
...VELSD | 1548 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt90829 |
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
GRAM_HUMAN | 1038 | EKLP.|.PTHP | inferred from experiment | unknown | MEROPS | Bovenschen N | de Poot SA et al.:Human and mouse granzyme M disp... (S01.139) | 21564021, |
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
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