Q9UPW0: Forkhead box protein J3

General Information

Protein names	- Forkhead box protein J3
Gene names	FOXJ3
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9UPW0

5 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MGLYGQACPS VTSLRMTSEL ESSLTSMDWL PQLTMRAAIQ KSDATQNAHG TGISKKNALL
        70         80         90        100        110        120
DPNTTLDQEE VQQHKDGKPP YSYASLITFA INSSPKKKMT LSEIYQWICD NFPYYREAGS
       130        140        150        160        170        180
GWKNSIRHNL SLNKCFLKVP RSKDDPGKGS YWAIDTNPKE DVLPTRPKKR ARSVERASTP
       190        200        210        220        230        240
YSIDSDSLGM ECIISGSASP TLAINTVTNK VTLYNTDQDG SDSPRSSLNN SLSDQSLASV
       250        260        270        280        290        300
NLNSVGSVHS YTPVTSHPES VSQSLTPQQQ PQYNLPERDK QLLFSEYNFE DLSASFRSLY
       310        320        330        340        350        360
KSVFEQSLSQ QGLMNIPSES SQQSHTSCTY QHSPSSTVST HPHSNQSSLS NSHGSGLNTT
       370        380        390        400        410        420
GSNSVAQVSL SHPQMHTQPS PHPPHRPHGL PQHPQRSPHP APHPQQHSQL QSPHPQHPSP
       430        440        450        460        470        480
HQHIQHHPNH QHQTLTHQAP PPPQQVSCNS GVSNDWYATL DMLKESCRIA SSVNWSDVDL
       490        500        510        520        530        540
SQFQGLMESM RQADLKNWSL DQVQFADLCS SLNQFFTQTG LIHSQSNVQQ NVCHGAMHPT
       550        560        570        580        590        600
KPSQHIGTGN LYIDSRQNLP PSVMPPPGYP HIPQALSTPG TTMAGHHRAM NQQHMMPSQA
       610        620
FQMRRSLPPD DIQDDFDWDS IV

Isoforms

- Isoform 2 of Forkhead box protein J3

Sequence View

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Protein Neighborhood

Domains & Features

5 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q9UPW0-1-unknown	MGLYGQ...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9UPW0-1-unknown	MGLYGQ...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt75383
Q9UPW0-203-	AINTVT...	203		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
Q9UPW0-203-	AINTVT...	203		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q9UPW0-203-	AINTVT...	203		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
Q9UPW0-214-unknown	YNTDQD...	214	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC15147
Q9UPW0-214-unknown	YNTDQD...	214	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt198175
Q9UPW0-247-unknown	SVHSYT...	247	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt175750
Q9UPW0-247-	SVHSYT...	247		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q9UPW0-247-	SVHSYT...	247		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...NKVTLY	213	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC15147
...WDSIV	622	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...WDSIV	622	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt71001

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAM_HUMAN	213	VTLY.\|.YNTD	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)