Q6ZN17: Protein lin-28 homolog B

General Information

Protein names	- Protein lin-28 homolog B - Lin-28B
Gene names	LIN28B
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q6ZN17

4 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAEGGASKGG GEEPGKLPEP AEEESQVLRG TGHCKWFNVR MGFGFISMIN REGSPLDIPV
        70         80         90        100        110        120
DVFVHQSKLF MEGFRSLKEG EPVEFTFKKS SKGLESIRVT GPGGSPCLGS ERRPKGKTLQ
       130        140        150        160        170        180
KRKPKGDRCY NCGGLDHHAK ECSLPPQPKK CHYCQSIMHM VANCPHKNVA QPPASSQGRQ
       190        200        210        220        230        240
EAESQPCTST LPREVGGGHG CTSPPFPQEA RAEISERSGR SPQEASSTKS SIAPEEQSKK
       250
GPSVQKRKKT

Isoforms

- Isoform 2 of Protein lin-28 homolog B

Sequence View

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Protein Neighborhood

Domains & Features

4 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q6ZN17-1-unknown	MAEGGA...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q6ZN17-2-acetylation	AEGGAS...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
Q6ZN17-71-unknown	MEGFRS...	71		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt79763
Q6ZN17-76-unknown	SLKEGE...	76		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC14635
Q6ZN17-76-unknown	SLKEGE...	76		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt196587

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...MEGFRS	75	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC14635
...KRKKT	250	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...KRKKT	250	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt75381

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAM_HUMAN	75	GFRS.\|.SLKE	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)