P24468: COUP transcription factor 2

General Information

Protein names	- COUP transcription factor 2 - COUP-TF2 - Apolipoprotein A-I regulatory protein 1 - ARP-1 - COUP transcription factor II - COUP-TF II - Nuclear receptor subfamily 2 group F member 2
Gene names	NR2F2
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P24468

4 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of COUP transcription factor 2 - Isoform 3 of COUP transcription factor 2

Sequence View

        10         20         30         40         50         60
MAMVVSTWRD PQDEVPGSQG SQASQAPPVP GPPPGAPHTP QTPGQGGPAS TPAQTAAGGQ
        70         80         90        100        110        120
GGPGGPGSDK QQQQQHIECV VCGDKSSGKH YGQFTCEGCK SFFKRSVRRN LSYTCRANRN
       130        140        150        160        170        180
CPIDQHHRNQ CQYCRLKKCL KVGMRREAVQ RGRMPPTQPT HGQFALTNGD PLNCHSYLSG
       190        200        210        220        230        240
YISLLLRAEP YPTSRFGSQC MQPNNIMGIE NICELAARML FSAVEWARNI PFFPDLQITD
       250        260        270        280        290        300
QVALLRLTWS ELFVLNAAQC SMPLHVAPLL AAAGLHASPM SADRVVAFMD HIRIFQEQVE
       310        320        330        340        350        360
KLKALHVDSA EYSCLKAIVL FTSDACGLSD VAHVESLQEK SQCALEEYVR SQYPNQPTRF
       370        380        390        400        410
GKLLLRLPSL RTVSSSVIEQ LFFVRLVGKT PIETLIRDML LSGSSFNWPY MAIQ         10         20         30         40         50         60
MAMVVSTWRD PQDEVPGSQG SQASQAPPVP GPPPGAPHTP QTPGQGGPAS TPAQTAAGGQ
        70         80         90        100        110        120
GGPGGPGSDK QQQQQHIECV VCGDKSSGKH YGQFTCEGCK SFFKRSVRRN LSYTCRANRN
       130        140        150        160        170        180
CPIDQHHRNQ CQYCRLKKCL KVGMRREAVQ RGRMPPTQPT HGQFALTNGD PLNCHSYLSG
       190        200        210        220        230        240
YISLLLRAEP YPTSRFGSQC MQPNNIMGIE NICELAARML FSAVEWARNI PFFPDLQITD
       250        260        270        280        290        300
QVALLRLTWS ELFVLNAAQC SMPLHVAPLL AAAGLHASPM SADRVVAFMD HIRIFQEQVE
       310        320        330        340        350        360
KLKALHVDSA EYSCLKAIVL FTSDACGLSD VAHVESLQEK SQCALEEYVR SQYPNQPTRF
       370        380        390        400        410
GKLLLRLPSL RTVSSSVIEQ LFFVRLVGKT PIETLIRDML LSGSSFNWPY MAIQ

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

4 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P24468-1-unknown	MAMVVS...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P24468-2-acetylation	AMVVST...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
P24468-154-unknown	MPPTQP...	154		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt71461
P24468-154-unknown	MPPTQP...	154		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt97938
P24468-205-unknown	NIMGIE...	205		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC14044
P24468-205-unknown	NIMGIE...	205		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt139359
P24468-205-unknown	NIMGIE...	205		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt140802

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...CMQPNN	204	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC14044
...CMQPNN	204	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt122436
...CMQPNN	204	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt123940
...YMAIQ	414	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...YMAIQ	414	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt67079
...YMAIQ	414	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt67078

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAM_HUMAN	204	QPNN.\|.NIMG	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)