Q9BTD8: RNA-binding protein 42

General Information

Protein names	- RNA-binding protein 42 - RNA-binding motif protein 42
Gene names	RBM42
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9BTD8

12 N-termini

3 C-termini

2 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of RNA-binding protein 42 - Isoform 3 of RNA-binding protein 42 - Isoform 4 of RNA-binding protein 42

Sequence View

        10         20         30         40         50         60
MAGAGPAPGL PGAGGPVVPG PGAGIPGKSG EERLKEMEAE MALFEQEVLG APVPGIPTAV
        70         80         90        100        110        120
PAVPTVPTVP TVEAMQVPAA PVIRPIIATN TYQQVQQTLE ARAAAAATVV PPMVGGPPFV
       130        140        150        160        170        180
GPVGFGPGDR SHLDSPEARE AMFLRRAAVA PQRAPILRPA FVPHVLQRAD SALSSAAAGP
       190        200        210        220        230        240
RPMALRPPHQ ALVGPPLPGP PGPPMMLPPM ARAPGPPLGS MAALRPPLEE PAAPRELGLG
       250        260        270        280        290        300
LGLGLKEKEE AVVAAAAGLE EASAAVAVGA GGAPAGPAVI GPSLPLALAM PLPEPEPLPL
       310        320        330        340        350        360
PLEVVRGLLP PLRIPELLSL RPRPRPPRPE PPPGLMALEV PEPLGEDKKK GKPEKLKRCI
       370        380        390        400        410        420
RTAAGSSWED PSLLEWDADD FRIFCGDLGN EVNDDILARA FSRFPSFLKA KVIRDKRTGK
       430        440        450        460        470        480
TKGYGFVSFK DPSDYVRAMR EMNGKYVGSR PIKLRKSMWK DRNLDVVRKK QKEKKKLGLR

        10         20         30         40         50         60
MAGAGPAPGL PGAGGPVVPG PGAGIPGKSG EERLKEMEAE MALFEQEVLG APVPGIPTAV
        70         80         90        100        110        120
PAVPTVPTVP TVEAMQVPAA PVIRPIIATN TYQQVQQTLE ARAAAAATVV PPMVGGPPFV
       130        140        150        160        170        180
GPVGFGPGDR SHLDSPEARE AMFLRRAAVA PQRAPILRPA FVPHVLQRAD SALSSAAAGP
       190        200        210        220        230        240
RPMALRPPHQ ALVGPPLPGP PGPPMMLPPM ARAPGPPLGS MAALRPPLEE PAAPRELGLG
       250        260        270        280        290        300
LGLGLKEKEE AVVAAAAGLE EASAAVAVGA GGAPAGPAVI GPSLPLALAM PLPEPEPLPL
       310        320        330        340        350        360
PLEVVRGLLP PLRIPELLSL RPRPRPPRPE PPPGLMALEV PEPLGEDKKK GKPEKLKRCI
       370        380        390        400        410        420
RTAAGSSWED PSLLEWDADD FRIFCGDLGN EVNDDILARA FSRFPSFLKA KVIRDKRTGK
       430        440        450        460        470        480
TKGYGFVSFK DPSDYVRAMR EMNGKYVGSR PIKLRKSMWK DRNLDVVRKK QKEKKKLGLR

        10         20         30         40         50         60
MAGAGPAPGL PGAGGPVVPG PGAGIPGKSG EERLKEMEAE MALFEQEVLG APVPGIPTAV
        70         80         90        100        110        120
PAVPTVPTVP TVEAMQVPAA PVIRPIIATN TYQQVQQTLE ARAAAAATVV PPMVGGPPFV
       130        140        150        160        170        180
GPVGFGPGDR SHLDSPEARE AMFLRRAAVA PQRAPILRPA FVPHVLQRAD SALSSAAAGP
       190        200        210        220        230        240
RPMALRPPHQ ALVGPPLPGP PGPPMMLPPM ARAPGPPLGS MAALRPPLEE PAAPRELGLG
       250        260        270        280        290        300
LGLGLKEKEE AVVAAAAGLE EASAAVAVGA GGAPAGPAVI GPSLPLALAM PLPEPEPLPL
       310        320        330        340        350        360
PLEVVRGLLP PLRIPELLSL RPRPRPPRPE PPPGLMALEV PEPLGEDKKK GKPEKLKRCI
       370        380        390        400        410        420
RTAAGSSWED PSLLEWDADD FRIFCGDLGN EVNDDILARA FSRFPSFLKA KVIRDKRTGK
       430        440        450        460        470        480
TKGYGFVSFK DPSDYVRAMR EMNGKYVGSR PIKLRKSMWK DRNLDVVRKK QKEKKKLGLR

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

12 N-termini - 3 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q9BTD8-1-unknown	MAGAGP...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt87133
Q9BTD8-1-unknown	MAGAGP...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt87134
Q9BTD8-1-unknown	MAGAGP...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt87135
Q9BTD8-2-unknown	MAGAGP...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9BTD8-2-Acetylation	AGAGPA...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9BTD8-2-Acetylation	AGAGPA...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
Q9BTD8-2-Acetylation	AGAGPA...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
Q9BTD8-2-Acetylation	AGAGPA...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt110589
Q9BTD8-2-Acetylation	AGAGPA...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt110590
Q9BTD8-2-Acetylation	AGAGPA...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt110591
Q9BTD8-223-unknown	ALRPPL...	223		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt170949
Q9BTD8-223-unknown	ALRPPL...	223		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt170951
Q9BTD8-223-unknown	ALRPPL...	223		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt170950
Q9BTD8-223-	ALRPPL...	223			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q9BTD8-223-	ALRPPL...	223			Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
Q9BTD8-272-unknown	GAPAGP...	272		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt177896
Q9BTD8-272-unknown	GAPAGP...	272		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt177898
Q9BTD8-272-unknown	GAPAGP...	272		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt177897
Q9BTD8-272-	GAPAGP...	272			Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
Q9BTD8-289-	AMPLPE...	289			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
Q9BTD8-289-	AMPLPE...	289			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q9BTD8-289-	AMPLPE...	289			Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
Q9BTD8-289-	AMPLPE...	289			Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
Q9BTD8-289-unknown	AMPLPE...	289		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC14938
Q9BTD8-289-unknown	AMPLPE...	289		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt148641
Q9BTD8-289-unknown	AMPLPE...	289		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt148770
Q9BTD8-289-unknown	AMPLPE...	289		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt148803
Q9BTD8-337-	ALEVPE...	337			Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
Q9BTD8-337-	ALEVPE...	337			Subtiligase Based Positive Selection		Wells	THP_untreated	23264352
Q9BTD8-337-unknown	ALEVPE...	337		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt169902
Q9BTD8-337-unknown	ALEVPE...	337		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt169904
Q9BTD8-337-unknown	ALEVPE...	337		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt169903
Q9BTD8-345-unknown	GEDKKK...	345		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC14942
Q9BTD8-345-unknown	GEDKKK...	345		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt150137
Q9BTD8-345-unknown	GEDKKK...	345		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt150223
Q9BTD8-345-unknown	GEDKKK...	345		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt150240

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...LPLALA	288	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC14938
...LPLALA	288	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt132015
...LPLALA	288	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt132146
...LPLALA	288	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt132179
...VPEPLG	344	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC14942
...VPEPLG	344	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt133529
...VPEPLG	344	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt133617
...VPEPLG	344	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt133633
...KLGLR	480	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...KLGLR	480	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt82753
...KLGLR	480	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt82751
...KLGLR	480	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt82752

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAM_HUMAN	288	LALA.\|.AMPL	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,
GRAM_HUMAN	344	EPLG.\|.GEDK	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)