O75334: Liprin-alpha-2

General Information

Protein names	- Liprin-alpha-2 - Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2 - PTPRF-interacting protein alpha-2
Gene names	PPFIA2
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	O75334

4 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Liprin-alpha-2 - Isoform 3 of Liprin-alpha-2 - Isoform 4 of Liprin-alpha-2 - Isoform 5 of Liprin-alpha-2 - Isoform 6 of Liprin-alpha-2 - Isoform 7 of Liprin-alpha-2 - Isoform 8 of Liprin-alpha-2

Sequence View

        10         20         30         40         50         60
MMCEVMPTIN EDTPMSQRGS QSSGSDSDSH FEQLMVNMLD ERDRLLDTLR ETQESLSLAQ
        70         80         90        100        110        120
QRLQDVIYDR DSLQRQLNSA LPQDIESLTG GLAGSKGADP PEFAALTKEL NACREQLLEK
       130        140        150        160        170        180
EEEISELKAE RNNTRLLLEH LECLVSRHER SLRMTVVKRQ AQSPSGVSSE VEVLKALKSL
       190        200        210        220        230        240
FEHHKALDEK VRERLRVSLE RVSALEEELA AANQEIVALR EQNVHIQRKM ASSEGSTESE
       250        260        270        280        290        300
HLEGMEPGQK VHEKRLSNGS IDSTDETSQI VELQELLEKQ NYEMAQMKER LAALSSRVGE
       310        320        330        340        350        360
VEQEAETARK DLIKTEEMNT KYQRDIREAM AQKEDMEERI TTLEKRYLSA QRESTSIHDM
       370        380        390        400        410        420
NDKLENELAN KEAILRQMEE KNRQLQERLE LAEQKLQQTM RKAETLPEVE AELAQRIAAL
       430        440        450        460        470        480
TKAEERHGNI EERMRHLEGQ LEEKNQELQR ARQREKMNEE HNKRLSDTVD RLLTESNERL
       490        500        510        520        530        540
QLHLKERMAA LEEKNVLIQE SETFRKNLEE SLHDKERLAE EIEKLRSELD QLKMRTGSLI
       550        560        570        580        590        600
EPTIPRTHLD TSAELRYSVG SLVDSQSDYR TTKVIRRPRR GRMGVRRDEP KVKSLGDHEW
       610        620        630        640        650        660
NRTQQIGVLS SHPFESDTEM SDIDDDDRET IFSSMDLLSP SGHSDAQTLA MMLQEQLDAI
       670        680        690        700        710        720
NKEIRLIQEE KESTELRAEE IENRVASVSL EGLNLARVHP GTSITASVTA SSLASSSPPS
       730        740        750        760        770        780
GHSTPKLTPR SPAREMDRMG VMTLPSDLRK HRRKIAVVEE DGREDKATIK CETSPPPTPR
       790        800        810        820        830        840
ALRMTHTLPS SYHNDARSSL SVSLEPESLG LGSANSSQDS LHKAPKKKGI KSSIGRLFGK
       850        860        870        880        890        900
KEKARLGQLR GFMETEAAAQ ESLGLGKLGT QAEKDRRLKK KHELLEEARR KGLPFAQWDG
       910        920        930        940        950        960
PTVVAWLELW LGMPAWYVAA CRANVKSGAI MSALSDTEIQ REIGISNPLH RLKLRLAIQE
       970        980        990       1000       1010       1020
MVSLTSPSAP PTSRTPSGNV WVTHEEMENL AAPAKTKESE EGSWAQCPVF LQTLAYGDMN
      1030       1040       1050       1060       1070       1080
HEWIGNEWLP SLGLPQYRSY FMECLVDARM LDHLTKKDLR VHLKMVDSFH RTSLQYGIMC
      1090       1100       1110       1120       1130       1140
LKRLNYDRKE LERRREASQH EIKDVLVWSN DRVIRWIQAI GLREYANNIL ESGVHGSLIA
      1150       1160       1170       1180       1190       1200
LDENFDYSSL ALLLQIPTQN TQARQILERE YNNLLALGTE RRLDESDDKN FRRGSTWRRQ
      1210       1220       1230       1240       1250
FPPREVHGIS MMPGSSETLP AGFRLTTTSG QSRKMTTDVA SSRLQRLDNS TVRTYSC         10         20         30         40         50         60
MMCEVMPTIN EDTPMSQRGS QSSGSDSDSH FEQLMVNMLD ERDRLLDTLR ETQESLSLAQ
        70         80         90        100        110        120
QRLQDVIYDR DSLQRQLNSA LPQDIESLTG GLAGSKGADP PEFAALTKEL NACREQLLEK
       130        140        150        160        170        180
EEEISELKAE RNNTRLLLEH LECLVSRHER SLRMTVVKRQ AQSPSGVSSE VEVLKALKSL
       190        200        210        220        230        240
FEHHKALDEK VRERLRVSLE RVSALEEELA AANQEIVALR EQNVHIQRKM ASSEGSTESE
       250        260        270        280        290        300
HLEGMEPGQK VHEKRLSNGS IDSTDETSQI VELQELLEKQ NYEMAQMKER LAALSSRVGE
       310        320        330        340        350        360
VEQEAETARK DLIKTEEMNT KYQRDIREAM AQKEDMEERI TTLEKRYLSA QRESTSIHDM
       370        380        390        400        410        420
NDKLENELAN KEAILRQMEE KNRQLQERLE LAEQKLQQTM RKAETLPEVE AELAQRIAAL
       430        440        450        460        470        480
TKAEERHGNI EERMRHLEGQ LEEKNQELQR ARQREKMNEE HNKRLSDTVD RLLTESNERL
       490        500        510        520        530        540
QLHLKERMAA LEEKNVLIQE SETFRKNLEE SLHDKERLAE EIEKLRSELD QLKMRTGSLI
       550        560        570        580        590        600
EPTIPRTHLD TSAELRYSVG SLVDSQSDYR TTKVIRRPRR GRMGVRRDEP KVKSLGDHEW
       610        620        630        640        650        660
NRTQQIGVLS SHPFESDTEM SDIDDDDRET IFSSMDLLSP SGHSDAQTLA MMLQEQLDAI
       670        680        690        700        710        720
NKEIRLIQEE KESTELRAEE IENRVASVSL EGLNLARVHP GTSITASVTA SSLASSSPPS
       730        740        750        760        770        780
GHSTPKLTPR SPAREMDRMG VMTLPSDLRK HRRKIAVVEE DGREDKATIK CETSPPPTPR
       790        800        810        820        830        840
ALRMTHTLPS SYHNDARSSL SVSLEPESLG LGSANSSQDS LHKAPKKKGI KSSIGRLFGK
       850        860        870        880        890        900
KEKARLGQLR GFMETEAAAQ ESLGLGKLGT QAEKDRRLKK KHELLEEARR KGLPFAQWDG
       910        920        930        940        950        960
PTVVAWLELW LGMPAWYVAA CRANVKSGAI MSALSDTEIQ REIGISNPLH RLKLRLAIQE
       970        980        990       1000       1010       1020
MVSLTSPSAP PTSRTPSGNV WVTHEEMENL AAPAKTKESE EGSWAQCPVF LQTLAYGDMN
      1030       1040       1050       1060       1070       1080
HEWIGNEWLP SLGLPQYRSY FMECLVDARM LDHLTKKDLR VHLKMVDSFH RTSLQYGIMC
      1090       1100       1110       1120       1130       1140
LKRLNYDRKE LERRREASQH EIKDVLVWSN DRVIRWIQAI GLREYANNIL ESGVHGSLIA
      1150       1160       1170       1180       1190       1200
LDENFDYSSL ALLLQIPTQN TQARQILERE YNNLLALGTE RRLDESDDKN FRRGSTWRRQ
      1210       1220       1230       1240       1250
FPPREVHGIS MMPGSSETLP AGFRLTTTSG QSRKMTTDVA SSRLQRLDNS TVRTYSC         10         20         30         40         50         60
MMCEVMPTIN EDTPMSQRGS QSSGSDSDSH FEQLMVNMLD ERDRLLDTLR ETQESLSLAQ
        70         80         90        100        110        120
QRLQDVIYDR DSLQRQLNSA LPQDIESLTG GLAGSKGADP PEFAALTKEL NACREQLLEK
       130        140        150        160        170        180
EEEISELKAE RNNTRLLLEH LECLVSRHER SLRMTVVKRQ AQSPSGVSSE VEVLKALKSL
       190        200        210        220        230        240
FEHHKALDEK VRERLRVSLE RVSALEEELA AANQEIVALR EQNVHIQRKM ASSEGSTESE
       250        260        270        280        290        300
HLEGMEPGQK VHEKRLSNGS IDSTDETSQI VELQELLEKQ NYEMAQMKER LAALSSRVGE
       310        320        330        340        350        360
VEQEAETARK DLIKTEEMNT KYQRDIREAM AQKEDMEERI TTLEKRYLSA QRESTSIHDM
       370        380        390        400        410        420
NDKLENELAN KEAILRQMEE KNRQLQERLE LAEQKLQQTM RKAETLPEVE AELAQRIAAL
       430        440        450        460        470        480
TKAEERHGNI EERMRHLEGQ LEEKNQELQR ARQREKMNEE HNKRLSDTVD RLLTESNERL
       490        500        510        520        530        540
QLHLKERMAA LEEKNVLIQE SETFRKNLEE SLHDKERLAE EIEKLRSELD QLKMRTGSLI
       550        560        570        580        590        600
EPTIPRTHLD TSAELRYSVG SLVDSQSDYR TTKVIRRPRR GRMGVRRDEP KVKSLGDHEW
       610        620        630        640        650        660
NRTQQIGVLS SHPFESDTEM SDIDDDDRET IFSSMDLLSP SGHSDAQTLA MMLQEQLDAI
       670        680        690        700        710        720
NKEIRLIQEE KESTELRAEE IENRVASVSL EGLNLARVHP GTSITASVTA SSLASSSPPS
       730        740        750        760        770        780
GHSTPKLTPR SPAREMDRMG VMTLPSDLRK HRRKIAVVEE DGREDKATIK CETSPPPTPR
       790        800        810        820        830        840
ALRMTHTLPS SYHNDARSSL SVSLEPESLG LGSANSSQDS LHKAPKKKGI KSSIGRLFGK
       850        860        870        880        890        900
KEKARLGQLR GFMETEAAAQ ESLGLGKLGT QAEKDRRLKK KHELLEEARR KGLPFAQWDG
       910        920        930        940        950        960
PTVVAWLELW LGMPAWYVAA CRANVKSGAI MSALSDTEIQ REIGISNPLH RLKLRLAIQE
       970        980        990       1000       1010       1020
MVSLTSPSAP PTSRTPSGNV WVTHEEMENL AAPAKTKESE EGSWAQCPVF LQTLAYGDMN
      1030       1040       1050       1060       1070       1080
HEWIGNEWLP SLGLPQYRSY FMECLVDARM LDHLTKKDLR VHLKMVDSFH RTSLQYGIMC
      1090       1100       1110       1120       1130       1140
LKRLNYDRKE LERRREASQH EIKDVLVWSN DRVIRWIQAI GLREYANNIL ESGVHGSLIA
      1150       1160       1170       1180       1190       1200
LDENFDYSSL ALLLQIPTQN TQARQILERE YNNLLALGTE RRLDESDDKN FRRGSTWRRQ
      1210       1220       1230       1240       1250
FPPREVHGIS MMPGSSETLP AGFRLTTTSG QSRKMTTDVA SSRLQRLDNS TVRTYSC         10         20         30         40         50         60
MMCEVMPTIN EDTPMSQRGS QSSGSDSDSH FEQLMVNMLD ERDRLLDTLR ETQESLSLAQ
        70         80         90        100        110        120
QRLQDVIYDR DSLQRQLNSA LPQDIESLTG GLAGSKGADP PEFAALTKEL NACREQLLEK
       130        140        150        160        170        180
EEEISELKAE RNNTRLLLEH LECLVSRHER SLRMTVVKRQ AQSPSGVSSE VEVLKALKSL
       190        200        210        220        230        240
FEHHKALDEK VRERLRVSLE RVSALEEELA AANQEIVALR EQNVHIQRKM ASSEGSTESE
       250        260        270        280        290        300
HLEGMEPGQK VHEKRLSNGS IDSTDETSQI VELQELLEKQ NYEMAQMKER LAALSSRVGE
       310        320        330        340        350        360
VEQEAETARK DLIKTEEMNT KYQRDIREAM AQKEDMEERI TTLEKRYLSA QRESTSIHDM
       370        380        390        400        410        420
NDKLENELAN KEAILRQMEE KNRQLQERLE LAEQKLQQTM RKAETLPEVE AELAQRIAAL
       430        440        450        460        470        480
TKAEERHGNI EERMRHLEGQ LEEKNQELQR ARQREKMNEE HNKRLSDTVD RLLTESNERL
       490        500        510        520        530        540
QLHLKERMAA LEEKNVLIQE SETFRKNLEE SLHDKERLAE EIEKLRSELD QLKMRTGSLI
       550        560        570        580        590        600
EPTIPRTHLD TSAELRYSVG SLVDSQSDYR TTKVIRRPRR GRMGVRRDEP KVKSLGDHEW
       610        620        630        640        650        660
NRTQQIGVLS SHPFESDTEM SDIDDDDRET IFSSMDLLSP SGHSDAQTLA MMLQEQLDAI
       670        680        690        700        710        720
NKEIRLIQEE KESTELRAEE IENRVASVSL EGLNLARVHP GTSITASVTA SSLASSSPPS
       730        740        750        760        770        780
GHSTPKLTPR SPAREMDRMG VMTLPSDLRK HRRKIAVVEE DGREDKATIK CETSPPPTPR
       790        800        810        820        830        840
ALRMTHTLPS SYHNDARSSL SVSLEPESLG LGSANSSQDS LHKAPKKKGI KSSIGRLFGK
       850        860        870        880        890        900
KEKARLGQLR GFMETEAAAQ ESLGLGKLGT QAEKDRRLKK KHELLEEARR KGLPFAQWDG
       910        920        930        940        950        960
PTVVAWLELW LGMPAWYVAA CRANVKSGAI MSALSDTEIQ REIGISNPLH RLKLRLAIQE
       970        980        990       1000       1010       1020
MVSLTSPSAP PTSRTPSGNV WVTHEEMENL AAPAKTKESE EGSWAQCPVF LQTLAYGDMN
      1030       1040       1050       1060       1070       1080
HEWIGNEWLP SLGLPQYRSY FMECLVDARM LDHLTKKDLR VHLKMVDSFH RTSLQYGIMC
      1090       1100       1110       1120       1130       1140
LKRLNYDRKE LERRREASQH EIKDVLVWSN DRVIRWIQAI GLREYANNIL ESGVHGSLIA
      1150       1160       1170       1180       1190       1200
LDENFDYSSL ALLLQIPTQN TQARQILERE YNNLLALGTE RRLDESDDKN FRRGSTWRRQ
      1210       1220       1230       1240       1250
FPPREVHGIS MMPGSSETLP AGFRLTTTSG QSRKMTTDVA SSRLQRLDNS TVRTYSC         10         20         30         40         50         60
MMCEVMPTIN EDTPMSQRGS QSSGSDSDSH FEQLMVNMLD ERDRLLDTLR ETQESLSLAQ
        70         80         90        100        110        120
QRLQDVIYDR DSLQRQLNSA LPQDIESLTG GLAGSKGADP PEFAALTKEL NACREQLLEK
       130        140        150        160        170        180
EEEISELKAE RNNTRLLLEH LECLVSRHER SLRMTVVKRQ AQSPSGVSSE VEVLKALKSL
       190        200        210        220        230        240
FEHHKALDEK VRERLRVSLE RVSALEEELA AANQEIVALR EQNVHIQRKM ASSEGSTESE
       250        260        270        280        290        300
HLEGMEPGQK VHEKRLSNGS IDSTDETSQI VELQELLEKQ NYEMAQMKER LAALSSRVGE
       310        320        330        340        350        360
VEQEAETARK DLIKTEEMNT KYQRDIREAM AQKEDMEERI TTLEKRYLSA QRESTSIHDM
       370        380        390        400        410        420
NDKLENELAN KEAILRQMEE KNRQLQERLE LAEQKLQQTM RKAETLPEVE AELAQRIAAL
       430        440        450        460        470        480
TKAEERHGNI EERMRHLEGQ LEEKNQELQR ARQREKMNEE HNKRLSDTVD RLLTESNERL
       490        500        510        520        530        540
QLHLKERMAA LEEKNVLIQE SETFRKNLEE SLHDKERLAE EIEKLRSELD QLKMRTGSLI
       550        560        570        580        590        600
EPTIPRTHLD TSAELRYSVG SLVDSQSDYR TTKVIRRPRR GRMGVRRDEP KVKSLGDHEW
       610        620        630        640        650        660
NRTQQIGVLS SHPFESDTEM SDIDDDDRET IFSSMDLLSP SGHSDAQTLA MMLQEQLDAI
       670        680        690        700        710        720
NKEIRLIQEE KESTELRAEE IENRVASVSL EGLNLARVHP GTSITASVTA SSLASSSPPS
       730        740        750        760        770        780
GHSTPKLTPR SPAREMDRMG VMTLPSDLRK HRRKIAVVEE DGREDKATIK CETSPPPTPR
       790        800        810        820        830        840
ALRMTHTLPS SYHNDARSSL SVSLEPESLG LGSANSSQDS LHKAPKKKGI KSSIGRLFGK
       850        860        870        880        890        900
KEKARLGQLR GFMETEAAAQ ESLGLGKLGT QAEKDRRLKK KHELLEEARR KGLPFAQWDG
       910        920        930        940        950        960
PTVVAWLELW LGMPAWYVAA CRANVKSGAI MSALSDTEIQ REIGISNPLH RLKLRLAIQE
       970        980        990       1000       1010       1020
MVSLTSPSAP PTSRTPSGNV WVTHEEMENL AAPAKTKESE EGSWAQCPVF LQTLAYGDMN
      1030       1040       1050       1060       1070       1080
HEWIGNEWLP SLGLPQYRSY FMECLVDARM LDHLTKKDLR VHLKMVDSFH RTSLQYGIMC
      1090       1100       1110       1120       1130       1140
LKRLNYDRKE LERRREASQH EIKDVLVWSN DRVIRWIQAI GLREYANNIL ESGVHGSLIA
      1150       1160       1170       1180       1190       1200
LDENFDYSSL ALLLQIPTQN TQARQILERE YNNLLALGTE RRLDESDDKN FRRGSTWRRQ
      1210       1220       1230       1240       1250
FPPREVHGIS MMPGSSETLP AGFRLTTTSG QSRKMTTDVA SSRLQRLDNS TVRTYSC         10         20         30         40         50         60
MMCEVMPTIN EDTPMSQRGS QSSGSDSDSH FEQLMVNMLD ERDRLLDTLR ETQESLSLAQ
        70         80         90        100        110        120
QRLQDVIYDR DSLQRQLNSA LPQDIESLTG GLAGSKGADP PEFAALTKEL NACREQLLEK
       130        140        150        160        170        180
EEEISELKAE RNNTRLLLEH LECLVSRHER SLRMTVVKRQ AQSPSGVSSE VEVLKALKSL
       190        200        210        220        230        240
FEHHKALDEK VRERLRVSLE RVSALEEELA AANQEIVALR EQNVHIQRKM ASSEGSTESE
       250        260        270        280        290        300
HLEGMEPGQK VHEKRLSNGS IDSTDETSQI VELQELLEKQ NYEMAQMKER LAALSSRVGE
       310        320        330        340        350        360
VEQEAETARK DLIKTEEMNT KYQRDIREAM AQKEDMEERI TTLEKRYLSA QRESTSIHDM
       370        380        390        400        410        420
NDKLENELAN KEAILRQMEE KNRQLQERLE LAEQKLQQTM RKAETLPEVE AELAQRIAAL
       430        440        450        460        470        480
TKAEERHGNI EERMRHLEGQ LEEKNQELQR ARQREKMNEE HNKRLSDTVD RLLTESNERL
       490        500        510        520        530        540
QLHLKERMAA LEEKNVLIQE SETFRKNLEE SLHDKERLAE EIEKLRSELD QLKMRTGSLI
       550        560        570        580        590        600
EPTIPRTHLD TSAELRYSVG SLVDSQSDYR TTKVIRRPRR GRMGVRRDEP KVKSLGDHEW
       610        620        630        640        650        660
NRTQQIGVLS SHPFESDTEM SDIDDDDRET IFSSMDLLSP SGHSDAQTLA MMLQEQLDAI
       670        680        690        700        710        720
NKEIRLIQEE KESTELRAEE IENRVASVSL EGLNLARVHP GTSITASVTA SSLASSSPPS
       730        740        750        760        770        780
GHSTPKLTPR SPAREMDRMG VMTLPSDLRK HRRKIAVVEE DGREDKATIK CETSPPPTPR
       790        800        810        820        830        840
ALRMTHTLPS SYHNDARSSL SVSLEPESLG LGSANSSQDS LHKAPKKKGI KSSIGRLFGK
       850        860        870        880        890        900
KEKARLGQLR GFMETEAAAQ ESLGLGKLGT QAEKDRRLKK KHELLEEARR KGLPFAQWDG
       910        920        930        940        950        960
PTVVAWLELW LGMPAWYVAA CRANVKSGAI MSALSDTEIQ REIGISNPLH RLKLRLAIQE
       970        980        990       1000       1010       1020
MVSLTSPSAP PTSRTPSGNV WVTHEEMENL AAPAKTKESE EGSWAQCPVF LQTLAYGDMN
      1030       1040       1050       1060       1070       1080
HEWIGNEWLP SLGLPQYRSY FMECLVDARM LDHLTKKDLR VHLKMVDSFH RTSLQYGIMC
      1090       1100       1110       1120       1130       1140
LKRLNYDRKE LERRREASQH EIKDVLVWSN DRVIRWIQAI GLREYANNIL ESGVHGSLIA
      1150       1160       1170       1180       1190       1200
LDENFDYSSL ALLLQIPTQN TQARQILERE YNNLLALGTE RRLDESDDKN FRRGSTWRRQ
      1210       1220       1230       1240       1250
FPPREVHGIS MMPGSSETLP AGFRLTTTSG QSRKMTTDVA SSRLQRLDNS TVRTYSC         10         20         30         40         50         60
MMCEVMPTIN EDTPMSQRGS QSSGSDSDSH FEQLMVNMLD ERDRLLDTLR ETQESLSLAQ
        70         80         90        100        110        120
QRLQDVIYDR DSLQRQLNSA LPQDIESLTG GLAGSKGADP PEFAALTKEL NACREQLLEK
       130        140        150        160        170        180
EEEISELKAE RNNTRLLLEH LECLVSRHER SLRMTVVKRQ AQSPSGVSSE VEVLKALKSL
       190        200        210        220        230        240
FEHHKALDEK VRERLRVSLE RVSALEEELA AANQEIVALR EQNVHIQRKM ASSEGSTESE
       250        260        270        280        290        300
HLEGMEPGQK VHEKRLSNGS IDSTDETSQI VELQELLEKQ NYEMAQMKER LAALSSRVGE
       310        320        330        340        350        360
VEQEAETARK DLIKTEEMNT KYQRDIREAM AQKEDMEERI TTLEKRYLSA QRESTSIHDM
       370        380        390        400        410        420
NDKLENELAN KEAILRQMEE KNRQLQERLE LAEQKLQQTM RKAETLPEVE AELAQRIAAL
       430        440        450        460        470        480
TKAEERHGNI EERMRHLEGQ LEEKNQELQR ARQREKMNEE HNKRLSDTVD RLLTESNERL
       490        500        510        520        530        540
QLHLKERMAA LEEKNVLIQE SETFRKNLEE SLHDKERLAE EIEKLRSELD QLKMRTGSLI
       550        560        570        580        590        600
EPTIPRTHLD TSAELRYSVG SLVDSQSDYR TTKVIRRPRR GRMGVRRDEP KVKSLGDHEW
       610        620        630        640        650        660
NRTQQIGVLS SHPFESDTEM SDIDDDDRET IFSSMDLLSP SGHSDAQTLA MMLQEQLDAI
       670        680        690        700        710        720
NKEIRLIQEE KESTELRAEE IENRVASVSL EGLNLARVHP GTSITASVTA SSLASSSPPS
       730        740        750        760        770        780
GHSTPKLTPR SPAREMDRMG VMTLPSDLRK HRRKIAVVEE DGREDKATIK CETSPPPTPR
       790        800        810        820        830        840
ALRMTHTLPS SYHNDARSSL SVSLEPESLG LGSANSSQDS LHKAPKKKGI KSSIGRLFGK
       850        860        870        880        890        900
KEKARLGQLR GFMETEAAAQ ESLGLGKLGT QAEKDRRLKK KHELLEEARR KGLPFAQWDG
       910        920        930        940        950        960
PTVVAWLELW LGMPAWYVAA CRANVKSGAI MSALSDTEIQ REIGISNPLH RLKLRLAIQE
       970        980        990       1000       1010       1020
MVSLTSPSAP PTSRTPSGNV WVTHEEMENL AAPAKTKESE EGSWAQCPVF LQTLAYGDMN
      1030       1040       1050       1060       1070       1080
HEWIGNEWLP SLGLPQYRSY FMECLVDARM LDHLTKKDLR VHLKMVDSFH RTSLQYGIMC
      1090       1100       1110       1120       1130       1140
LKRLNYDRKE LERRREASQH EIKDVLVWSN DRVIRWIQAI GLREYANNIL ESGVHGSLIA
      1150       1160       1170       1180       1190       1200
LDENFDYSSL ALLLQIPTQN TQARQILERE YNNLLALGTE RRLDESDDKN FRRGSTWRRQ
      1210       1220       1230       1240       1250
FPPREVHGIS MMPGSSETLP AGFRLTTTSG QSRKMTTDVA SSRLQRLDNS TVRTYSC

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

4 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
O75334-1-unknown	MMCEVM...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
O75334-1-unknown	MMCEVM...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt79628
O75334-1-unknown	MMCEVM...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt79629
O75334-1-unknown	MMCEVM...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt79630
O75334-434-unknown	MRHLEG...	434	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt79633
O75334-434-unknown	MRHLEG...	434	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt96842
O75334-434-unknown	MRHLEG...	434	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt96843
O75334-434-unknown	MRHLEG...	434	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt96846
O75334-434-unknown	MRHLEG...	434	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt96844
O75334-434-unknown	MRHLEG...	434	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt96845
O75334-784-unknown	MTHTLP...	784	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt79634
O75334-784-unknown	MTHTLP...	784	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt96917
O75334-784-unknown	MTHTLP...	784	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt96918
O75334-784-unknown	MTHTLP...	784	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt96919
O75334-784-unknown	MTHTLP...	784	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt96922
O75334-784-unknown	MTHTLP...	784	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt96920
O75334-784-unknown	MTHTLP...	784	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt96921
O75334-840-unknown	KKEKAR...	840	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC13823
O75334-840-unknown	KKEKAR...	840	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt139632
O75334-840-unknown	KKEKAR...	840	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt152093
O75334-840-unknown	KKEKAR...	840	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt156220
O75334-840-unknown	KKEKAR...	840	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt156341
O75334-840-unknown	KKEKAR...	840	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt156573
O75334-840-unknown	KKEKAR...	840	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt156647
O75334-840-unknown	KKEKAR...	840	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt156648

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...GRLFGK	839	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC13823
...GRLFGK	839	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt122727
...GRLFGK	839	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt135502
...GRLFGK	839	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt139686
...GRLFGK	839	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt139814
...GRLFGK	839	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt140057
...GRLFGK	839	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt140132
...GRLFGK	839	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt140133
...RTYSC	1257	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...RTYSC	1257	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt75252
...RTYSC	1257	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt75250
...RTYSC	1257	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt75249
...RTYSC	1257	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt75248
...RTYSC	1257	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt75247

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAM_HUMAN	839	LFGK.\|.KKEK	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)