Q9NSV4: Protein diaphanous homolog 3

General Information

Protein names	- Protein diaphanous homolog 3 - Diaphanous-related formin-3 - DRF3 - MDia2
Gene names	DIAPH3
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9NSV4

5 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 1 of Protein diaphanous homolog 3 - Isoform 2 of Protein diaphanous homolog 3 - Isoform 4 of Protein diaphanous homolog 3 - Isoform 5 of Protein diaphanous homolog 3 - Isoform 6 of Protein diaphanous homolog 3 - Isoform 7 of Protein diaphanous homolog 3

Sequence View

        10         20         30         40         50         60
MERHQPRLHH PAQGSAAGTP YPSSASLRGC RESKMPRRKG PQHPPPPSGP EEPGEKRPKF
        70         80         90        100        110        120
HLNIRTLTDD MLDKFASIRI PGSKKERPPL PNLKTAFASS DCSAAPLEMM ENFPKPLSEN
       130        140        150        160        170        180
ELLELFEKMM EDMNLNEDKK APLREKDFSI KKEMVMQYIN TASKTGSLKR SRQISPQEFI
       190        200        210        220        230        240
HELKMGSADE RLVTCLESLR VSLTSNPVSW VESFGHEGLG LLLDILEKLI SGKIQEKVVK
       250        260        270        280        290        300
KNQHKVIQCL KALMNTQYGL ERIMSEERSL SLLAKAVDPR HPNMMTDVVK LLSAVCIVGE
       310        320        330        340        350        360
ESILEEVLEA LTSAGEEKKI DRFFCIVEGL RHNSVQLQVA CMQLINALVT SPDDLDFRLH
       370        380        390        400        410        420
IRNEFMRCGL KEILPNLKCI KNDGLDIQLK VFDEHKEEDL FELSHRLEDI RAELDEAYDV
       430        440        450        460        470        480
YNMVWSTVKE TRAEGYFISI LQHLLLIRND YFIRQQYFKL IDECVSQIVL HRDGMDPDFT
       490        500        510        520        530        540
YRKRLDLDLT QFVDICIDQA KLEEFEEKAS ELYKKFEKEF TDHQETQAEL QKKEAKINEL
       550        560        570        580        590        600
QAELQAFKSQ FGALPADCNI PLPPSKEGGT GHSALPPPPP LPSGGGVPPP PPPPPPPPLP
       610        620        630        640        650        660
GMRMPFSGPV PPPPPLGFLG GQNSPPLPIL PFGLKPKKEF KPEISMRRLN WLKIRPHEMT
       670        680        690        700        710        720
ENCFWIKVNE NKYENVDLLC KLENTFCCQQ KERREEEDIE EKKSIKKKIK ELKFLDSKIA
       730        740        750        760        770        780
QNLSIFLSSF RVPYEEIRMM ILEVDETRLA ESMIQNLIKH LPDQEQLNSL SQFKSEYSNL
       790        800        810        820        830        840
CEPEQFVVVM SNVKRLRPRL SAILFKLQFE EQVNNIKPDI MAVSTACEEI KKSKSFSKLL
       850        860        870        880        890        900
ELVLLMGNYM NAGSRNAQTF GFNLSSLCKL KDTKSADQKT TLLHFLVEIC EEKYPDILNF
       910        920        930        940        950        960
VDDLEPLDKA SKVSVETLEK NLRQMGRQLQ QLEKELETFP PPEDLHDKFV TKMSRFVISA
       970        980        990       1000       1010       1020
KEQYETLSKL HENMEKLYQS IIGYYAIDVK KVSVEDFLTD LNNFRTTFMQ AIKENIKKRE
      1030       1040       1050       1060       1070       1080
AEEKEKRVRI AKELAERERL ERQQKKKRLL EMKTEGDETG VMDNLLEALQ SGAAFRDRRK
      1090       1100       1110       1120       1130       1140
RTPMPKDVRQ SLSPMSQRPV LKVCNHENQK VQLTEGSRSH YNINCNSTRT PVAKELNYNL
      1150       1160       1170       1180       1190
DTHTSTGRIK AAEKKEACNV ESNRKKETEL LGSFSKNESV PEVEALLARL RAL         10         20         30         40         50         60
MERHQPRLHH PAQGSAAGTP YPSSASLRGC RESKMPRRKG PQHPPPPSGP EEPGEKRPKF
        70         80         90        100        110        120
HLNIRTLTDD MLDKFASIRI PGSKKERPPL PNLKTAFASS DCSAAPLEMM ENFPKPLSEN
       130        140        150        160        170        180
ELLELFEKMM EDMNLNEDKK APLREKDFSI KKEMVMQYIN TASKTGSLKR SRQISPQEFI
       190        200        210        220        230        240
HELKMGSADE RLVTCLESLR VSLTSNPVSW VESFGHEGLG LLLDILEKLI SGKIQEKVVK
       250        260        270        280        290        300
KNQHKVIQCL KALMNTQYGL ERIMSEERSL SLLAKAVDPR HPNMMTDVVK LLSAVCIVGE
       310        320        330        340        350        360
ESILEEVLEA LTSAGEEKKI DRFFCIVEGL RHNSVQLQVA CMQLINALVT SPDDLDFRLH
       370        380        390        400        410        420
IRNEFMRCGL KEILPNLKCI KNDGLDIQLK VFDEHKEEDL FELSHRLEDI RAELDEAYDV
       430        440        450        460        470        480
YNMVWSTVKE TRAEGYFISI LQHLLLIRND YFIRQQYFKL IDECVSQIVL HRDGMDPDFT
       490        500        510        520        530        540
YRKRLDLDLT QFVDICIDQA KLEEFEEKAS ELYKKFEKEF TDHQETQAEL QKKEAKINEL
       550        560        570        580        590        600
QAELQAFKSQ FGALPADCNI PLPPSKEGGT GHSALPPPPP LPSGGGVPPP PPPPPPPPLP
       610        620        630        640        650        660
GMRMPFSGPV PPPPPLGFLG GQNSPPLPIL PFGLKPKKEF KPEISMRRLN WLKIRPHEMT
       670        680        690        700        710        720
ENCFWIKVNE NKYENVDLLC KLENTFCCQQ KERREEEDIE EKKSIKKKIK ELKFLDSKIA
       730        740        750        760        770        780
QNLSIFLSSF RVPYEEIRMM ILEVDETRLA ESMIQNLIKH LPDQEQLNSL SQFKSEYSNL
       790        800        810        820        830        840
CEPEQFVVVM SNVKRLRPRL SAILFKLQFE EQVNNIKPDI MAVSTACEEI KKSKSFSKLL
       850        860        870        880        890        900
ELVLLMGNYM NAGSRNAQTF GFNLSSLCKL KDTKSADQKT TLLHFLVEIC EEKYPDILNF
       910        920        930        940        950        960
VDDLEPLDKA SKVSVETLEK NLRQMGRQLQ QLEKELETFP PPEDLHDKFV TKMSRFVISA
       970        980        990       1000       1010       1020
KEQYETLSKL HENMEKLYQS IIGYYAIDVK KVSVEDFLTD LNNFRTTFMQ AIKENIKKRE
      1030       1040       1050       1060       1070       1080
AEEKEKRVRI AKELAERERL ERQQKKKRLL EMKTEGDETG VMDNLLEALQ SGAAFRDRRK
      1090       1100       1110       1120       1130       1140
RTPMPKDVRQ SLSPMSQRPV LKVCNHENQK VQLTEGSRSH YNINCNSTRT PVAKELNYNL
      1150       1160       1170       1180       1190
DTHTSTGRIK AAEKKEACNV ESNRKKETEL LGSFSKNESV PEVEALLARL RAL         10         20         30         40         50         60
MERHQPRLHH PAQGSAAGTP YPSSASLRGC RESKMPRRKG PQHPPPPSGP EEPGEKRPKF
        70         80         90        100        110        120
HLNIRTLTDD MLDKFASIRI PGSKKERPPL PNLKTAFASS DCSAAPLEMM ENFPKPLSEN
       130        140        150        160        170        180
ELLELFEKMM EDMNLNEDKK APLREKDFSI KKEMVMQYIN TASKTGSLKR SRQISPQEFI
       190        200        210        220        230        240
HELKMGSADE RLVTCLESLR VSLTSNPVSW VESFGHEGLG LLLDILEKLI SGKIQEKVVK
       250        260        270        280        290        300
KNQHKVIQCL KALMNTQYGL ERIMSEERSL SLLAKAVDPR HPNMMTDVVK LLSAVCIVGE
       310        320        330        340        350        360
ESILEEVLEA LTSAGEEKKI DRFFCIVEGL RHNSVQLQVA CMQLINALVT SPDDLDFRLH
       370        380        390        400        410        420
IRNEFMRCGL KEILPNLKCI KNDGLDIQLK VFDEHKEEDL FELSHRLEDI RAELDEAYDV
       430        440        450        460        470        480
YNMVWSTVKE TRAEGYFISI LQHLLLIRND YFIRQQYFKL IDECVSQIVL HRDGMDPDFT
       490        500        510        520        530        540
YRKRLDLDLT QFVDICIDQA KLEEFEEKAS ELYKKFEKEF TDHQETQAEL QKKEAKINEL
       550        560        570        580        590        600
QAELQAFKSQ FGALPADCNI PLPPSKEGGT GHSALPPPPP LPSGGGVPPP PPPPPPPPLP
       610        620        630        640        650        660
GMRMPFSGPV PPPPPLGFLG GQNSPPLPIL PFGLKPKKEF KPEISMRRLN WLKIRPHEMT
       670        680        690        700        710        720
ENCFWIKVNE NKYENVDLLC KLENTFCCQQ KERREEEDIE EKKSIKKKIK ELKFLDSKIA
       730        740        750        760        770        780
QNLSIFLSSF RVPYEEIRMM ILEVDETRLA ESMIQNLIKH LPDQEQLNSL SQFKSEYSNL
       790        800        810        820        830        840
CEPEQFVVVM SNVKRLRPRL SAILFKLQFE EQVNNIKPDI MAVSTACEEI KKSKSFSKLL
       850        860        870        880        890        900
ELVLLMGNYM NAGSRNAQTF GFNLSSLCKL KDTKSADQKT TLLHFLVEIC EEKYPDILNF
       910        920        930        940        950        960
VDDLEPLDKA SKVSVETLEK NLRQMGRQLQ QLEKELETFP PPEDLHDKFV TKMSRFVISA
       970        980        990       1000       1010       1020
KEQYETLSKL HENMEKLYQS IIGYYAIDVK KVSVEDFLTD LNNFRTTFMQ AIKENIKKRE
      1030       1040       1050       1060       1070       1080
AEEKEKRVRI AKELAERERL ERQQKKKRLL EMKTEGDETG VMDNLLEALQ SGAAFRDRRK
      1090       1100       1110       1120       1130       1140
RTPMPKDVRQ SLSPMSQRPV LKVCNHENQK VQLTEGSRSH YNINCNSTRT PVAKELNYNL
      1150       1160       1170       1180       1190
DTHTSTGRIK AAEKKEACNV ESNRKKETEL LGSFSKNESV PEVEALLARL RAL         10         20         30         40         50         60
MERHQPRLHH PAQGSAAGTP YPSSASLRGC RESKMPRRKG PQHPPPPSGP EEPGEKRPKF
        70         80         90        100        110        120
HLNIRTLTDD MLDKFASIRI PGSKKERPPL PNLKTAFASS DCSAAPLEMM ENFPKPLSEN
       130        140        150        160        170        180
ELLELFEKMM EDMNLNEDKK APLREKDFSI KKEMVMQYIN TASKTGSLKR SRQISPQEFI
       190        200        210        220        230        240
HELKMGSADE RLVTCLESLR VSLTSNPVSW VESFGHEGLG LLLDILEKLI SGKIQEKVVK
       250        260        270        280        290        300
KNQHKVIQCL KALMNTQYGL ERIMSEERSL SLLAKAVDPR HPNMMTDVVK LLSAVCIVGE
       310        320        330        340        350        360
ESILEEVLEA LTSAGEEKKI DRFFCIVEGL RHNSVQLQVA CMQLINALVT SPDDLDFRLH
       370        380        390        400        410        420
IRNEFMRCGL KEILPNLKCI KNDGLDIQLK VFDEHKEEDL FELSHRLEDI RAELDEAYDV
       430        440        450        460        470        480
YNMVWSTVKE TRAEGYFISI LQHLLLIRND YFIRQQYFKL IDECVSQIVL HRDGMDPDFT
       490        500        510        520        530        540
YRKRLDLDLT QFVDICIDQA KLEEFEEKAS ELYKKFEKEF TDHQETQAEL QKKEAKINEL
       550        560        570        580        590        600
QAELQAFKSQ FGALPADCNI PLPPSKEGGT GHSALPPPPP LPSGGGVPPP PPPPPPPPLP
       610        620        630        640        650        660
GMRMPFSGPV PPPPPLGFLG GQNSPPLPIL PFGLKPKKEF KPEISMRRLN WLKIRPHEMT
       670        680        690        700        710        720
ENCFWIKVNE NKYENVDLLC KLENTFCCQQ KERREEEDIE EKKSIKKKIK ELKFLDSKIA
       730        740        750        760        770        780
QNLSIFLSSF RVPYEEIRMM ILEVDETRLA ESMIQNLIKH LPDQEQLNSL SQFKSEYSNL
       790        800        810        820        830        840
CEPEQFVVVM SNVKRLRPRL SAILFKLQFE EQVNNIKPDI MAVSTACEEI KKSKSFSKLL
       850        860        870        880        890        900
ELVLLMGNYM NAGSRNAQTF GFNLSSLCKL KDTKSADQKT TLLHFLVEIC EEKYPDILNF
       910        920        930        940        950        960
VDDLEPLDKA SKVSVETLEK NLRQMGRQLQ QLEKELETFP PPEDLHDKFV TKMSRFVISA
       970        980        990       1000       1010       1020
KEQYETLSKL HENMEKLYQS IIGYYAIDVK KVSVEDFLTD LNNFRTTFMQ AIKENIKKRE
      1030       1040       1050       1060       1070       1080
AEEKEKRVRI AKELAERERL ERQQKKKRLL EMKTEGDETG VMDNLLEALQ SGAAFRDRRK
      1090       1100       1110       1120       1130       1140
RTPMPKDVRQ SLSPMSQRPV LKVCNHENQK VQLTEGSRSH YNINCNSTRT PVAKELNYNL
      1150       1160       1170       1180       1190
DTHTSTGRIK AAEKKEACNV ESNRKKETEL LGSFSKNESV PEVEALLARL RAL         10         20         30         40         50         60
MERHQPRLHH PAQGSAAGTP YPSSASLRGC RESKMPRRKG PQHPPPPSGP EEPGEKRPKF
        70         80         90        100        110        120
HLNIRTLTDD MLDKFASIRI PGSKKERPPL PNLKTAFASS DCSAAPLEMM ENFPKPLSEN
       130        140        150        160        170        180
ELLELFEKMM EDMNLNEDKK APLREKDFSI KKEMVMQYIN TASKTGSLKR SRQISPQEFI
       190        200        210        220        230        240
HELKMGSADE RLVTCLESLR VSLTSNPVSW VESFGHEGLG LLLDILEKLI SGKIQEKVVK
       250        260        270        280        290        300
KNQHKVIQCL KALMNTQYGL ERIMSEERSL SLLAKAVDPR HPNMMTDVVK LLSAVCIVGE
       310        320        330        340        350        360
ESILEEVLEA LTSAGEEKKI DRFFCIVEGL RHNSVQLQVA CMQLINALVT SPDDLDFRLH
       370        380        390        400        410        420
IRNEFMRCGL KEILPNLKCI KNDGLDIQLK VFDEHKEEDL FELSHRLEDI RAELDEAYDV
       430        440        450        460        470        480
YNMVWSTVKE TRAEGYFISI LQHLLLIRND YFIRQQYFKL IDECVSQIVL HRDGMDPDFT
       490        500        510        520        530        540
YRKRLDLDLT QFVDICIDQA KLEEFEEKAS ELYKKFEKEF TDHQETQAEL QKKEAKINEL
       550        560        570        580        590        600
QAELQAFKSQ FGALPADCNI PLPPSKEGGT GHSALPPPPP LPSGGGVPPP PPPPPPPPLP
       610        620        630        640        650        660
GMRMPFSGPV PPPPPLGFLG GQNSPPLPIL PFGLKPKKEF KPEISMRRLN WLKIRPHEMT
       670        680        690        700        710        720
ENCFWIKVNE NKYENVDLLC KLENTFCCQQ KERREEEDIE EKKSIKKKIK ELKFLDSKIA
       730        740        750        760        770        780
QNLSIFLSSF RVPYEEIRMM ILEVDETRLA ESMIQNLIKH LPDQEQLNSL SQFKSEYSNL
       790        800        810        820        830        840
CEPEQFVVVM SNVKRLRPRL SAILFKLQFE EQVNNIKPDI MAVSTACEEI KKSKSFSKLL
       850        860        870        880        890        900
ELVLLMGNYM NAGSRNAQTF GFNLSSLCKL KDTKSADQKT TLLHFLVEIC EEKYPDILNF
       910        920        930        940        950        960
VDDLEPLDKA SKVSVETLEK NLRQMGRQLQ QLEKELETFP PPEDLHDKFV TKMSRFVISA
       970        980        990       1000       1010       1020
KEQYETLSKL HENMEKLYQS IIGYYAIDVK KVSVEDFLTD LNNFRTTFMQ AIKENIKKRE
      1030       1040       1050       1060       1070       1080
AEEKEKRVRI AKELAERERL ERQQKKKRLL EMKTEGDETG VMDNLLEALQ SGAAFRDRRK
      1090       1100       1110       1120       1130       1140
RTPMPKDVRQ SLSPMSQRPV LKVCNHENQK VQLTEGSRSH YNINCNSTRT PVAKELNYNL
      1150       1160       1170       1180       1190
DTHTSTGRIK AAEKKEACNV ESNRKKETEL LGSFSKNESV PEVEALLARL RAL         10         20         30         40         50         60
MERHQPRLHH PAQGSAAGTP YPSSASLRGC RESKMPRRKG PQHPPPPSGP EEPGEKRPKF
        70         80         90        100        110        120
HLNIRTLTDD MLDKFASIRI PGSKKERPPL PNLKTAFASS DCSAAPLEMM ENFPKPLSEN
       130        140        150        160        170        180
ELLELFEKMM EDMNLNEDKK APLREKDFSI KKEMVMQYIN TASKTGSLKR SRQISPQEFI
       190        200        210        220        230        240
HELKMGSADE RLVTCLESLR VSLTSNPVSW VESFGHEGLG LLLDILEKLI SGKIQEKVVK
       250        260        270        280        290        300
KNQHKVIQCL KALMNTQYGL ERIMSEERSL SLLAKAVDPR HPNMMTDVVK LLSAVCIVGE
       310        320        330        340        350        360
ESILEEVLEA LTSAGEEKKI DRFFCIVEGL RHNSVQLQVA CMQLINALVT SPDDLDFRLH
       370        380        390        400        410        420
IRNEFMRCGL KEILPNLKCI KNDGLDIQLK VFDEHKEEDL FELSHRLEDI RAELDEAYDV
       430        440        450        460        470        480
YNMVWSTVKE TRAEGYFISI LQHLLLIRND YFIRQQYFKL IDECVSQIVL HRDGMDPDFT
       490        500        510        520        530        540
YRKRLDLDLT QFVDICIDQA KLEEFEEKAS ELYKKFEKEF TDHQETQAEL QKKEAKINEL
       550        560        570        580        590        600
QAELQAFKSQ FGALPADCNI PLPPSKEGGT GHSALPPPPP LPSGGGVPPP PPPPPPPPLP
       610        620        630        640        650        660
GMRMPFSGPV PPPPPLGFLG GQNSPPLPIL PFGLKPKKEF KPEISMRRLN WLKIRPHEMT
       670        680        690        700        710        720
ENCFWIKVNE NKYENVDLLC KLENTFCCQQ KERREEEDIE EKKSIKKKIK ELKFLDSKIA
       730        740        750        760        770        780
QNLSIFLSSF RVPYEEIRMM ILEVDETRLA ESMIQNLIKH LPDQEQLNSL SQFKSEYSNL
       790        800        810        820        830        840
CEPEQFVVVM SNVKRLRPRL SAILFKLQFE EQVNNIKPDI MAVSTACEEI KKSKSFSKLL
       850        860        870        880        890        900
ELVLLMGNYM NAGSRNAQTF GFNLSSLCKL KDTKSADQKT TLLHFLVEIC EEKYPDILNF
       910        920        930        940        950        960
VDDLEPLDKA SKVSVETLEK NLRQMGRQLQ QLEKELETFP PPEDLHDKFV TKMSRFVISA
       970        980        990       1000       1010       1020
KEQYETLSKL HENMEKLYQS IIGYYAIDVK KVSVEDFLTD LNNFRTTFMQ AIKENIKKRE
      1030       1040       1050       1060       1070       1080
AEEKEKRVRI AKELAERERL ERQQKKKRLL EMKTEGDETG VMDNLLEALQ SGAAFRDRRK
      1090       1100       1110       1120       1130       1140
RTPMPKDVRQ SLSPMSQRPV LKVCNHENQK VQLTEGSRSH YNINCNSTRT PVAKELNYNL
      1150       1160       1170       1180       1190
DTHTSTGRIK AAEKKEACNV ESNRKKETEL LGSFSKNESV PEVEALLARL RAL

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

5 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q9NSV4-1-unknown	MERHQP...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9NSV4-1-unknown	MERHQP...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt72783
Q9NSV4-1-unknown	MERHQP...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt72784
Q9NSV4-1-unknown	MERHQP...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt72785
Q9NSV4-1-unknown	MERHQP...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt72786
Q9NSV4-15-	SAAGTP...	15		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
Q9NSV4-15-unknown	SAAGTP...	15	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt178481
Q9NSV4-15-unknown	SAAGTP...	15	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt178482
Q9NSV4-15-unknown	SAAGTP...	15	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt178483
Q9NSV4-15-unknown	SAAGTP...	15	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt178484
Q9NSV4-264-unknown	MSEERS...	264	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt72782
Q9NSV4-264-unknown	MSEERS...	264	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt100305
Q9NSV4-264-unknown	MSEERS...	264	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt100306
Q9NSV4-264-unknown	MSEERS...	264	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt100307
Q9NSV4-264-unknown	MSEERS...	264	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt100304
Q9NSV4-1159-unknown	NVESNR...	1159	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC15043
Q9NSV4-1159-unknown	NVESNR...	1159	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt157350
Q9NSV4-1159-unknown	NVESNR...	1159	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt157429
Q9NSV4-1159-unknown	NVESNR...	1159	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt157501

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...KKEACN	1158	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC15043
...KKEACN	1158	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt140849
...KKEACN	1158	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt140927
...KKEACN	1158	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt140999
...RLRAL	1193	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...RLRAL	1193	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt68403
...RLRAL	1193	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt68402
...RLRAL	1193	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt68401

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAM_HUMAN	1158	EACN.\|.NVES	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)