O43293: Death-associated protein kinase 3

General Information

Protein names	- Death-associated protein kinase 3 - DAP kinase 3 - 2.7.11.1 {ECO:0000269\|PubMed:10356987, ECO:0000269\|PubMed:11384979, ECO:0000269\|PubMed:11781833, ECO:0000269\|PubMed:15096528, ECO:0000269\|PubMed:17126281, ECO:0000269\|PubMed:18995835} - DAP-like kinase - Dlk - MYPT1 kinase - Zipper-interacting protein kinase - ZIP-kinase
Gene names	DAPK3
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	O43293

2 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MSTFRQEDVE DHYEMGEELG SGQFAIVRKC RQKGTGKEYA AKFIKKRRLS SSRRGVSREE
        70         80         90        100        110        120
IEREVNILRE IRHPNIITLH DIFENKTDVV LILELVSGGE LFDFLAEKES LTEDEATQFL
       130        140        150        160        170        180
KQILDGVHYL HSKRIAHFDL KPENIMLLDK NVPNPRIKLI DFGIAHKIEA GNEFKNIFGT
       190        200        210        220        230        240
PEFVAPEIVN YEPLGLEADM WSIGVITYIL LSGASPFLGE TKQETLTNIS AVNYDFDEEY
       250        260        270        280        290        300
FSNTSELAKD FIRRLLVKDP KRRMTIAQSL EHSWIKAIRR RNVRGEDSGR KPERRRLKTT
       310        320        330        340        350        360
RLKEYTIKSH SSLPPNNSYA DFERFSKVLE EAAAAEEGLR ELQRSRRLCH EDVEALAAIY
       370        380        390        400        410        420
EEKEAWYREE SDSLGQDLRR LRQELLKTEA LKRQAQEEAK GALLGTSGLK RRFSRLENRY
       430        440        450
EALAKQVASE MRFVQDLVRA LEQEKLQGVE CGLR

Isoforms

- Isoform 2 of Death-associated protein kinase 3

Sequence View

Protein Neighborhood

Domains & Features

2 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
O43293-1-unknown	MSTFRQ...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
O43293-1-unknown	MSTFRQ...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt72347
O43293-42-unknown	KFIKKR...	42	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC13749
O43293-42-unknown	KFIKKR...	42	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt138530

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...KEYAAK	41	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC13749
...KEYAAK	41	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt121578
...ECGLR	454	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAM_HUMAN	41	YAAK.\|.KFIK	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

TopFIND

O43293: Death-associated protein kinase 3

General Information

2

N-termini

2

C-termini

1

Cleavages

0

Substrates

Sequence

Isoforms

Filter Information:

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Physiological Relevance:

Evidence Codes:

Methodology:

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Biological System:

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Protein Neighborhood

Domains & Features

2 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates