TopFIND 4.0

Q9Y5A9: YTH domain-containing family protein 2 {ECO:0000305}

General Information

Protein names
- YTH domain-containing family protein 2 {ECO:0000305}
- CLL-associated antigen KW-14 {ECO:0000303|Ref.3}
- High-glucose-regulated protein 8 {ECO:0000303|Ref.2}
- Renal carcinoma antigen NY-REN-2 {ECO:0000303|PubMed:10508479}
Gene names YTHDF2
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q9Y5A9

25

N-termini

2

C-termini

1

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MSASSLLEQR PKGQGNKVQN GSVHQKDGLN DDDFEPYLSP QARPNNAYTA MSDSYLPSYY 
        70         80         90        100        110        120 
SPSIGFSYSL GEAAWSTGGD TAMPYLTSYG QLSNGEPHFL PDAMFGQPGA LGSTPFLGQH 
       130        140        150        160        170        180 
GFNFFPSGID FSAWGNNSSQ GQSTQSSGYS SNYAYAPSSL GGAMIDGQSA FANETLNKAP 
       190        200        210        220        230        240 
GMNTIDQGMA ALKLGSTEVA SNVPKVVGSA VGSGSITSNI VASNSLPPAT IAPPKPASWA 
       250        260        270        280        290        300 
DIASKPAKQQ PKLKTKNGIA GSSLPPPPIK HNMDIGTWDN KGPVAKAPSQ ALVQNIGQPT 
       310        320        330        340        350        360 
QGSPQPVGQQ ANNSPPVAQA SVGQQTQPLP PPPPQPAQLS VQQQAAQPTR WVAPRNRGSG 
       370        380        390        400        410        420 
FGHNGVDGNG VGQSQAGSGS TPSEPHPVLE KLRSINNYNP KDFDWNLKHG RVFIIKSYSE 
       430        440        450        460        470        480 
DDIHRSIKYN IWCSTEHGNK RLDAAYRSMN GKGPVYLLFS VNGSGHFCGV AEMKSAVDYN 
       490        500        510        520        530        540 
TCAGVWSQDK WKGRFDVRWI FVKDVPNSQL RHIRLENNEN KPVTNSRDTQ EVPLEKAKQV 
       550        560        570    
LKIIASYKHT TSIFDDFSHY EKRQEEEESV KKERQGRGK

Isoforms

- Isoform 2 of YTH domain-containing family protein 2

Sequence View

        10         20         30         40         50         60 
MSASSLLEQR PKGQGNKVQN GSVHQKDGLN DDDFEPYLSP QARPNNAYTA MSDSYLPSYY 
        70         80         90        100        110        120 
SPSIGFSYSL GEAAWSTGGD TAMPYLTSYG QLSNGEPHFL PDAMFGQPGA LGSTPFLGQH 
       130        140        150        160        170        180 
GFNFFPSGID FSAWGNNSSQ GQSTQSSGYS SNYAYAPSSL GGAMIDGQSA FANETLNKAP 
       190        200        210        220        230        240 
GMNTIDQGMA ALKLGSTEVA SNVPKVVGSA VGSGSITSNI VASNSLPPAT IAPPKPASWA 
       250        260        270        280        290        300 
DIASKPAKQQ PKLKTKNGIA GSSLPPPPIK HNMDIGTWDN KGPVAKAPSQ ALVQNIGQPT 
       310        320        330        340        350        360 
QGSPQPVGQQ ANNSPPVAQA SVGQQTQPLP PPPPQPAQLS VQQQAAQPTR WVAPRNRGSG 
       370        380        390        400        410        420 
FGHNGVDGNG VGQSQAGSGS TPSEPHPVLE KLRSINNYNP KDFDWNLKHG RVFIIKSYSE 
       430        440        450        460        470        480 
DDIHRSIKYN IWCSTEHGNK RLDAAYRSMN GKGPVYLLFS VNGSGHFCGV AEMKSAVDYN 
       490        500        510        520        530        540 
TCAGVWSQDK WKGRFDVRWI FVKDVPNSQL RHIRLENNEN KPVTNSRDTQ EVPLEKAKQV 
       550        560        570    
LKIIASYKHT TSIFDDFSHY EKRQEEEESV KKERQGRGK



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(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


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Protease Assignment Confidence:


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Protein Neighborhood

Domains & Features

25 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)