P10074: Telomere zinc finger-associated protein {ECO:0000303|PubMed:28082411}

General Information

Protein names	- Telomere zinc finger-associated protein {ECO:0000303\|PubMed:28082411} - TZAP {ECO:0000303\|PubMed:28082411} - Krueppel-related zinc finger protein 3 {ECO:0000303\|PubMed:9516840} - hKR3 {ECO:0000303\|Ref.12} - Zinc finger and BTB domain-containing protein 48 {ECO:0000312\|HGNC:HGNC:4930} - Zinc finger protein 855 {ECO:0000312\|HGNC:HGNC:4930}
Gene names	ZBTB48
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P10074

3 N-termini

5 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MDGSFVQHSV RVLQELNKQR EKGQYCDATL DVGGLVFKAH WSVLACCSHF FQSLYGDGSG
        70         80         90        100        110        120
GSVVLPAGFA EIFGLLLDFF YTGHLALTSG NRDQVLLAAR ELRVPEAVEL CQSFKPKTSV
       130        140        150        160        170        180
GQAAGGQSGL GPPASQNVNS HVKEPAGLEE EEVSRTLGLV PRDQEPRGSH SPQRPQLHSP
       190        200        210        220        230        240
AQSEGPSSLC GKLKQALKPC PLEDKKPEDC KVPPRPLEAE GAQLQGGSNE WEVVVQVEDD
       250        260        270        280        290        300
GDGDYMSEPE AVLTRRKSNV IRKPCAAEPA LSAGSLAAEP AENRKGTAVP VECPTCHKKF
       310        320        330        340        350        360
LSKYYLKVHN RKHTGEKPFE CPKCGKCYFR KENLLEHEAR NCMNRSEQVF TCSVCQETFR
       370        380        390        400        410        420
RRMELRVHMV SHTGEMPYKC SSCSQQFMQK KDLQSHMIKL HGAPKPHACP TCAKCFLSRT
       430        440        450        460        470        480
ELQLHEAFKH RGEKLFVCEE CGHRASSRNG LQMHIKAKHR NERPHVCEFC SHAFTQKANL
       490        500        510        520        530        540
NMHLRTHTGE KPFQCHLCGK TFRTQASLDK HNRTHTGERP FSCEFCEQRF TEKGPLLRHV
       550        560        570        580        590        600
ASRHQEGRPH FCQICGKTFK AVEQLRVHVR RHKGVRKFEC TECGYKFTRQ AHLRRHMEIH
       610        620        630        640        650        660
DRVENYNPRQ RKLRNLIIED EKMVVVALQP PAELEVGSAE VIVESLAQGG LASQLPGQRL
       670        680
CAEESFTGPG VLEPSLIITA AVPEDCDT

Isoforms

Sequence View

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(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

3 N-termini - 5 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
P10074-1-unknown	MDGSFV...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P10074-246-unknown	MSEPEA...	246	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000466390
P10074-266-unknown	AAEPAL...	266	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC13957

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...IRKPCA	265	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC13957
...AVPVEC	292	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000416054
...LKVHNR	310	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000313416
...SHAFTQ	475	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000466390
...EDCDT	688	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAM_HUMAN	265	KPCA.\|.AAEP	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)