Q9NY27: Serine/threonine-protein phosphatase 4 regulatory subunit 2
Protein names | - Serine/threonine-protein phosphatase 4 regulatory subunit 2 |
---|---|
Gene names | PPP4R2 |
Organism | Homo sapiens |
Protease Family | |
Protease ID | |
Chromosome location | |
UniProt ID | Q9NY27 |
7
N-termini
2
C-termini
1
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MDVERLQEAL KDFEKRGKKE VCPVLDQFLC HVAKTGETMI QWSQFKGYFI FKLEKVMDDF
70 80 90 100 110 120
RTSAPEPRGP PNPNVEYIPF DEMKERILKI VTGFNGIPFT IQRLCELLTD PRRNYTGTDK
130 140 150 160 170 180
FLRGVEKNVM VVSCVYPSSE KNNSNSLNRM NGVMFPGNSP SYTERSNING PGTPRPLNRP
190 200 210 220 230 240
KVSLSAPMTT NGLPESTDSK EANLQQNEEK NHSDSSTSES EVSSVSPLKN KHPDEDAVEA
250 260 270 280 290 300
EGHEVKRLRF DKEGEVRETA SQTTSSEISS VMVGETEASS SSQDKDKDSR CTRQHCTEED
310 320 330 340 350 360
EEEDEEEEEE SFMTSREMIP ERKNQEKESD DALTVNEETS EENNQMEESD VSQAEKDLLH
370 380 390 400 410
SEGSENEGPV SSSSSDCRET EELVGSNSSK TGEILSESSM ENDDEATEVT DEPMEQD
Isoforms
- Isoform 2 of Serine/threonine-protein phosphatase 4 regulatory subunit 2 - Isoform 3 of Serine/threonine-protein phosphatase 4 regulatory subunit 2Sequence View
10 20 30 40 50 60
MDVERLQEAL KDFEKRGKKE VCPVLDQFLC HVAKTGETMI QWSQFKGYFI FKLEKVMDDF
70 80 90 100 110 120
RTSAPEPRGP PNPNVEYIPF DEMKERILKI VTGFNGIPFT IQRLCELLTD PRRNYTGTDK
130 140 150 160 170 180
FLRGVEKNVM VVSCVYPSSE KNNSNSLNRM NGVMFPGNSP SYTERSNING PGTPRPLNRP
190 200 210 220 230 240
KVSLSAPMTT NGLPESTDSK EANLQQNEEK NHSDSSTSES EVSSVSPLKN KHPDEDAVEA
250 260 270 280 290 300
EGHEVKRLRF DKEGEVRETA SQTTSSEISS VMVGETEASS SSQDKDKDSR CTRQHCTEED
310 320 330 340 350 360
EEEDEEEEEE SFMTSREMIP ERKNQEKESD DALTVNEETS EENNQMEESD VSQAEKDLLH
370 380 390 400 410
SEGSENEGPV SSSSSDCRET EELVGSNSSK TGEILSESSM ENDDEATEVT DEPMEQD
10 20 30 40 50 60
MDVERLQEAL KDFEKRGKKE VCPVLDQFLC HVAKTGETMI QWSQFKGYFI FKLEKVMDDF
70 80 90 100 110 120
RTSAPEPRGP PNPNVEYIPF DEMKERILKI VTGFNGIPFT IQRLCELLTD PRRNYTGTDK
130 140 150 160 170 180
FLRGVEKNVM VVSCVYPSSE KNNSNSLNRM NGVMFPGNSP SYTERSNING PGTPRPLNRP
190 200 210 220 230 240
KVSLSAPMTT NGLPESTDSK EANLQQNEEK NHSDSSTSES EVSSVSPLKN KHPDEDAVEA
250 260 270 280 290 300
EGHEVKRLRF DKEGEVRETA SQTTSSEISS VMVGETEASS SSQDKDKDSR CTRQHCTEED
310 320 330 340 350 360
EEEDEEEEEE SFMTSREMIP ERKNQEKESD DALTVNEETS EENNQMEESD VSQAEKDLLH
370 380 390 400 410
SEGSENEGPV SSSSSDCRET EELVGSNSSK TGEILSESSM ENDDEATEVT DEPMEQD
Protein Neighborhood
Domains & Features
7 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
Q9NY27-1-unknown | MDVERL... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
Q9NY27-1-unknown | MDVERL... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt85869 | |||
Q9NY27-57-unknown | MDDFRT... | 57 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt85870 | |||
Q9NY27-266- | SEISSV... | 266 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_bortezomib | 23264352 | |||
Q9NY27-266-unknown | SEISSV... | 266 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt167063 | |||
Q9NY27-266-unknown | SEISSV... | 266 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt167062 | |||
Q9NY27-270-unknown | SVMVGE... | 270 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt167060 | |||
Q9NY27-270-unknown | SVMVGE... | 270 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt167059 | |||
Q9NY27-270- | SVMVGE... | 270 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_bortezomib | 23264352 | |||
Q9NY27-270- | SVMVGE... | 270 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
Q9NY27-270- | SVMVGE... | 270 | Subtiligase Based Positive Selection | Wells | apoptosis_U266_bortezomib_induced | 23264352 | |||
Q9NY27-360-unknown | HSEGSE... | 360 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC15067 | |||
Q9NY27-360-unknown | HSEGSE... | 360 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt149964 | |||
Q9NY27-360-unknown | HSEGSE... | 360 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt149991 |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...EKDLLH | 359 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC15067 | |||
...EKDLLH | 359 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt133356 | |||
...EKDLLH | 359 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt133383 | |||
...PMEQD | 417 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
...PMEQD | 417 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt81487 | |||
...PMEQD | 417 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt81488 |
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
GRAM_HUMAN | 359 | DLLH.|.HSEG | inferred from experiment | unknown | MEROPS | Bovenschen N | de Poot SA et al.:Human and mouse granzyme M disp... (S01.139) | 21564021, |
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
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