Q9NZT2: Opioid growth factor receptor

General Information

Protein names	- Opioid growth factor receptor - OGFr - Protein 7-60 - Zeta-type opioid receptor
Gene names	OGFR
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9NZT2

9 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MDDPDCDSTW EEDEEDAEDA EDEDCEDGEA AGARDADAGD EDEESEEPRA ARPSSFQSRM
        70         80         90        100        110        120
TGSRNWRATR DMCRYRHNYP DLVERDCNGD TPNLSFYRNE IRFLPNGCFI EDILQNWTDN
       130        140        150        160        170        180
YDLLEDNHSY IQWLFPLREP GVNWHAKPLT LREVEVFKSS QEIQERLVRA YELMLGFYGI
       190        200        210        220        230        240
RLEDRGTGTV GRAQNYQKRF QNLNWRSHNN LRITRILKSL GELGLEHFQA PLVRFFLEET
       250        260        270        280        290        300
LVRRELPGVR QSALDYFMFA VRCRHQRRQL VHFAWEHFRP RCKFVWGPQD KLRRFKPSSL
       310        320        330        340        350        360
PHPLEGSRKV EEEGSPGDPD HEASTQGRTC GPEHSKGGGR VDEGPQPRSV EPQDAGPLER
       370        380        390        400        410        420
SQGDEAGGHG EDRPEPLSPK ESKKRKLELS RREQPPTEPG PQSASEVEKI ALNLEGCALS
       430        440        450        460        470        480
QGSLRTGTQE VGGQDPGEAV QPCRQPLGAR VADKVRKRRK VDEGAGDSAA VASGGAQTLA
       490        500        510        520        530        540
LAGSPAPSGH PKAGHSENGV EEDTEGRTGP KEGTPGSPSE TPGPSPAGPA GDEPAESPSE
       550        560        570        580        590        600
TPGPRPAGPA GDEPAESPSE TPGPRPAGPA GDEPAESPSE TPGPSPAGPT RDEPAESPSE
       610        620        630        640        650        660
TPGPRPAGPA GDEPAESPSE TPGPRPAGPA GDEPAESPSE TPGPSPAGPT RDEPAKAGEA
       670
AELQDAEVES SAKSGKP

Isoforms

- Isoform 2 of Opioid growth factor receptor

Sequence View

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Protein Neighborhood

Domains & Features

9 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q9NZT2-1-Acetylation	MDDPDC...	1	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9NZT2-1-Acetylation	MDDPDC...	1	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt96250
Q9NZT2-1-unknown	MDDPDC...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt83728
Q9NZT2-349-	SVEPQD...	349			Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
Q9NZT2-349-unknown	SVEPQD...	349		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt177055
Q9NZT2-413-unknown	NLEGCA...	413		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC15082
Q9NZT2-413-unknown	NLEGCA...	413		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt152215
Q9NZT2-480-	ALAGSP...	480			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
Q9NZT2-480-	ALAGSP...	480			Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q9NZT2-480-unknown	ALAGSP...	480		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt168656
Q9NZT2-481-	LAGSPA...	481			Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q9NZT2-481-unknown	LAGSPA...	481		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt175726

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...EKIALN	412	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC15082
...EKIALN	412	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt135625
...KSGKP	677	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...KSGKP	677	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt79346

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAM_HUMAN	412	IALN.\|.NLEG	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)