Q96T17: MAP7 domain-containing protein 2

General Information

Protein names	- MAP7 domain-containing protein 2
Gene names	MAP7D2
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q96T17

3 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of MAP7 domain-containing protein 2 - Isoform 3 of MAP7 domain-containing protein 2 - Isoform 4 of MAP7 domain-containing protein 2 - Isoform 5 of MAP7 domain-containing protein 2

Sequence View

        10         20         30         40         50         60
MERGGGGSGT GSRPEGTARG TSLPGKIAEP GAVRTSQPNY RPQGMEGFLK SDERQRLAKE
        70         80         90        100        110        120
RREEREKCLA AREQQILEKQ KRARLQYEKQ MEERWRKLEE QRQREDQKRA AVEEKRKQKL
       130        140        150        160        170        180
REEEERLEAM MRRSLERTQQ LELKKKYSWG APLAIGPGGH DACDKLSTST MSLPKPTEPP
       190        200        210        220        230        240
MNKRLSSSTV AISYSPDRVF HVCPRLAPLG PLNPSYKSSP TRNIEKKKAT STSTSGAGDV
       250        260        270        280        290        300
GKEALSGGEA SLVEKVKRGQ RTATSLPVVN FGSPLRRCEF SGGIPKRPSS PVISKTATKA
       310        320        330        340        350        360
YPQSPKTTKP PYPGSPVKYR LPALSGQDMP KRKAEKEKSN KEREGTLAQQ AAGPQGEEAL
       370        380        390        400        410        420
EKHVVDKHAS EKHAAAAGGK AENSAALGKP TAGTTDAGEA AKILAEKRRQ ARLQKEQEEQ
       430        440        450        460        470        480
ERLEKEEQDR LEREELKRKA EEERLRLEEE ARKQEEERKR QEEEKKKQEG EEKRKAGEEA
       490        500        510        520        530        540
KRKAEEELLL KEKQEQEKQE KAMIEKQKEA AETKAREVAE QMRLEREQIM LQIEQERLER
       550        560        570        580        590        600
KKRIDEIMKR TRKSDVSPQV KKEDPKVGVQ PAVCVEKKTK LVVPNKMEIN GLNTCQEVNG
       610        620        630        640        650        660
VDHAAPETYP QDIFSNGLKP AGGLIHLDAL DGKSNSLDDS TEEVQSMDVS PVSKEELISI
       670        680        690        700        710        720
PEFSPVSEMI PGVSLDQNGT GNARALQDLL DFTGPPTFPK RSSENLSLDD CNKNLIEGFN
       730
SPGQETPLNT FC         10         20         30         40         50         60
MERGGGGSGT GSRPEGTARG TSLPGKIAEP GAVRTSQPNY RPQGMEGFLK SDERQRLAKE
        70         80         90        100        110        120
RREEREKCLA AREQQILEKQ KRARLQYEKQ MEERWRKLEE QRQREDQKRA AVEEKRKQKL
       130        140        150        160        170        180
REEEERLEAM MRRSLERTQQ LELKKKYSWG APLAIGPGGH DACDKLSTST MSLPKPTEPP
       190        200        210        220        230        240
MNKRLSSSTV AISYSPDRVF HVCPRLAPLG PLNPSYKSSP TRNIEKKKAT STSTSGAGDV
       250        260        270        280        290        300
GKEALSGGEA SLVEKVKRGQ RTATSLPVVN FGSPLRRCEF SGGIPKRPSS PVISKTATKA
       310        320        330        340        350        360
YPQSPKTTKP PYPGSPVKYR LPALSGQDMP KRKAEKEKSN KEREGTLAQQ AAGPQGEEAL
       370        380        390        400        410        420
EKHVVDKHAS EKHAAAAGGK AENSAALGKP TAGTTDAGEA AKILAEKRRQ ARLQKEQEEQ
       430        440        450        460        470        480
ERLEKEEQDR LEREELKRKA EEERLRLEEE ARKQEEERKR QEEEKKKQEG EEKRKAGEEA
       490        500        510        520        530        540
KRKAEEELLL KEKQEQEKQE KAMIEKQKEA AETKAREVAE QMRLEREQIM LQIEQERLER
       550        560        570        580        590        600
KKRIDEIMKR TRKSDVSPQV KKEDPKVGVQ PAVCVEKKTK LVVPNKMEIN GLNTCQEVNG
       610        620        630        640        650        660
VDHAAPETYP QDIFSNGLKP AGGLIHLDAL DGKSNSLDDS TEEVQSMDVS PVSKEELISI
       670        680        690        700        710        720
PEFSPVSEMI PGVSLDQNGT GNARALQDLL DFTGPPTFPK RSSENLSLDD CNKNLIEGFN
       730
SPGQETPLNT FC         10         20         30         40         50         60
MERGGGGSGT GSRPEGTARG TSLPGKIAEP GAVRTSQPNY RPQGMEGFLK SDERQRLAKE
        70         80         90        100        110        120
RREEREKCLA AREQQILEKQ KRARLQYEKQ MEERWRKLEE QRQREDQKRA AVEEKRKQKL
       130        140        150        160        170        180
REEEERLEAM MRRSLERTQQ LELKKKYSWG APLAIGPGGH DACDKLSTST MSLPKPTEPP
       190        200        210        220        230        240
MNKRLSSSTV AISYSPDRVF HVCPRLAPLG PLNPSYKSSP TRNIEKKKAT STSTSGAGDV
       250        260        270        280        290        300
GKEALSGGEA SLVEKVKRGQ RTATSLPVVN FGSPLRRCEF SGGIPKRPSS PVISKTATKA
       310        320        330        340        350        360
YPQSPKTTKP PYPGSPVKYR LPALSGQDMP KRKAEKEKSN KEREGTLAQQ AAGPQGEEAL
       370        380        390        400        410        420
EKHVVDKHAS EKHAAAAGGK AENSAALGKP TAGTTDAGEA AKILAEKRRQ ARLQKEQEEQ
       430        440        450        460        470        480
ERLEKEEQDR LEREELKRKA EEERLRLEEE ARKQEEERKR QEEEKKKQEG EEKRKAGEEA
       490        500        510        520        530        540
KRKAEEELLL KEKQEQEKQE KAMIEKQKEA AETKAREVAE QMRLEREQIM LQIEQERLER
       550        560        570        580        590        600
KKRIDEIMKR TRKSDVSPQV KKEDPKVGVQ PAVCVEKKTK LVVPNKMEIN GLNTCQEVNG
       610        620        630        640        650        660
VDHAAPETYP QDIFSNGLKP AGGLIHLDAL DGKSNSLDDS TEEVQSMDVS PVSKEELISI
       670        680        690        700        710        720
PEFSPVSEMI PGVSLDQNGT GNARALQDLL DFTGPPTFPK RSSENLSLDD CNKNLIEGFN
       730
SPGQETPLNT FC         10         20         30         40         50         60
MERGGGGSGT GSRPEGTARG TSLPGKIAEP GAVRTSQPNY RPQGMEGFLK SDERQRLAKE
        70         80         90        100        110        120
RREEREKCLA AREQQILEKQ KRARLQYEKQ MEERWRKLEE QRQREDQKRA AVEEKRKQKL
       130        140        150        160        170        180
REEEERLEAM MRRSLERTQQ LELKKKYSWG APLAIGPGGH DACDKLSTST MSLPKPTEPP
       190        200        210        220        230        240
MNKRLSSSTV AISYSPDRVF HVCPRLAPLG PLNPSYKSSP TRNIEKKKAT STSTSGAGDV
       250        260        270        280        290        300
GKEALSGGEA SLVEKVKRGQ RTATSLPVVN FGSPLRRCEF SGGIPKRPSS PVISKTATKA
       310        320        330        340        350        360
YPQSPKTTKP PYPGSPVKYR LPALSGQDMP KRKAEKEKSN KEREGTLAQQ AAGPQGEEAL
       370        380        390        400        410        420
EKHVVDKHAS EKHAAAAGGK AENSAALGKP TAGTTDAGEA AKILAEKRRQ ARLQKEQEEQ
       430        440        450        460        470        480
ERLEKEEQDR LEREELKRKA EEERLRLEEE ARKQEEERKR QEEEKKKQEG EEKRKAGEEA
       490        500        510        520        530        540
KRKAEEELLL KEKQEQEKQE KAMIEKQKEA AETKAREVAE QMRLEREQIM LQIEQERLER
       550        560        570        580        590        600
KKRIDEIMKR TRKSDVSPQV KKEDPKVGVQ PAVCVEKKTK LVVPNKMEIN GLNTCQEVNG
       610        620        630        640        650        660
VDHAAPETYP QDIFSNGLKP AGGLIHLDAL DGKSNSLDDS TEEVQSMDVS PVSKEELISI
       670        680        690        700        710        720
PEFSPVSEMI PGVSLDQNGT GNARALQDLL DFTGPPTFPK RSSENLSLDD CNKNLIEGFN
       730
SPGQETPLNT FC

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

3 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q96T17-1-unknown	MERGGG...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q96T17-1-unknown	MERGGG...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt80223
Q96T17-1-unknown	MERGGG...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt80224
Q96T17-1-unknown	MERGGG...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt80225
Q96T17-45-unknown	MEGFLK...	45	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt80226
Q96T17-45-unknown	MEGFLK...	45	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt101469
Q96T17-45-unknown	MEGFLK...	45	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt101470
Q96T17-45-unknown	MEGFLK...	45	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt101471
Q96T17-86-unknown	QYEKQM...	86	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC14874
Q96T17-86-unknown	QYEKQM...	86	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt138490
Q96T17-86-unknown	QYEKQM...	86	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt141616
Q96T17-86-unknown	QYEKQM...	86	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt141617
Q96T17-86-unknown	QYEKQM...	86	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt141618

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...KRARLQ	85	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC14874
...KRARLQ	85	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt121534
...KRARLQ	85	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt124794
...KRARLQ	85	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt124795
...KRARLQ	85	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt124796
...LNTFC	732	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...LNTFC	732	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt75844
...LNTFC	732	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt75843
...LNTFC	732	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt75841

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAM_HUMAN	85	ARLQ.\|.QYEK	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)