Q96HA1: Nuclear envelope pore membrane protein POM 121

General Information

Protein names	- Nuclear envelope pore membrane protein POM 121 - Nuclear envelope pore membrane protein POM 121A - Nucleoporin Nup121 - Pore membrane protein of 121 kDa
Gene names	POM121
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q96HA1

3 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MSPAAAAAGA GERRRPIASV RDGRGRGCGG PARAVLLGLS LVGLLLYLVP AAAALAWLTV
        70         80         90        100        110        120
GATAAWWGLS REPRGSRPLS SFVRKARHRR PLSSFVRKAR HRRTLFASPL AKSTANGNLL
       130        140        150        160        170        180
EPRTLLEGPD PAELLLMGSY LGKPGPPQPA AAPEGQDLRD RPGRRPPARP APRSPPPRSP
       190        200        210        220        230        240
PPRSPPPSPP THRAHHVYPS LPTPLLRPSR RPSPRDCGTL PNRFVITPRR RYPIHQAQYS
       250        260        270        280        290        300
CLGVLPTVCW NGYHKKAVLS PRNSRMVCSP VTVRIAPPDR RFSRSAIPEQ IISSTLSSPS
       310        320        330        340        350        360
SNAPDPCAKE TVLSALKEKE KKRTVEEEDQ IFLDGQENKR RRHDSSGSGH SAFEPLVANG
       370        380        390        400        410        420
VPASFVPKPG SLKRGLNSQS SDDHLNKRSR SSSMSSLTGA YASGIPSSSR NAITSSYSST
       430        440        450        460        470        480
RGISQLWKRN GPSSSPFSSP ASSRSQTPER PAKKIREEEL CHHSSSSTPL AADRESQGEK
       490        500        510        520        530        540
AADTTPRKKQ NSNSQSTPGS SGQRKRKVQL LPSRRGEQLT LPPPPQLGYS ITAEDLDLEK
       550        560        570        580        590        600
KASLQWFNQA LEDKSDAASN SVTETPPITQ PSFTFTLPAA APASPPTSLL APSTNPLLES
       610        620        630        640        650        660
LKKMQTPPSL PPCPESAGAA TTEALSPPKT PSLLPPLGLS QSGPPGLLPS PSFDSKPPTT
       670        680        690        700        710        720
LLGLIPAPSM VPATDTKAPP TLQAETATKP QATSAPSPAP KQSFLFGTQN TSPSSPAAPA
       730        740        750        760        770        780
ASSAPPMFKP IFTAPPKSEK EGPTPPGPSV TATAPSSSSL PTTTSTTAPT FQPVFSSMGP
       790        800        810        820        830        840
PASVPLPAPF FKQTTTPATA PTTTAPLFTG LASATSAVAP ITSASPSTDS ASKPAFGFGI
       850        860        870        880        890        900
NSVSSSSVST TTSTATAASQ PFLFGAPQAS AASFTPAMGS IFQFGKPPAL PTTTTVTTFS
       910        920        930        940        950        960
QSLHTAVPTA TSSSAADFSG FGSTLATSAP ATSSQPTLTF SNTSTPTFNI PFGSSAKSPL
       970        980        990       1000       1010       1020
PSYPGANPQP AFGAAEGQPP GAAKPALAPS FGSSFTFGNS AAPAAAPTPA PPSMIKVVPA
      1030       1040       1050       1060       1070       1080
YVPTPIHPIF GGATHSAFGL KATASAFGAP ASSQPAFGGS TAVFFGAATS SGFGATTQTA
      1090       1100       1110       1120       1130       1140
SSGSSSSVFG STTPSPFTFG GSAAPAGSGS FGINVATPGS STTTGAFSFG AGQSGSTATS
      1150       1160       1170       1180       1190       1200
TPFAGGLGQN ALGTTGQSTP FAFNVSSTTE SKPVFGGTAT PTFGLNTPAP GVGTSGSSLS
      1210       1220       1230       1240
FGASSAPAQG FVGVAPFGSA ALSFSIGAGS KTPGARQRLQ ARRQHTRKK

Isoforms

- Isoform 2 of Nuclear envelope pore membrane protein POM 121 - Isoform 3 of Nuclear envelope pore membrane protein POM 121

Sequence View

        10         20         30         40         50         60
MSPAAAAAGA GERRRPIASV RDGRGRGCGG PARAVLLGLS LVGLLLYLVP AAAALAWLTV
        70         80         90        100        110        120
GATAAWWGLS REPRGSRPLS SFVRKARHRR PLSSFVRKAR HRRTLFASPL AKSTANGNLL
       130        140        150        160        170        180
EPRTLLEGPD PAELLLMGSY LGKPGPPQPA AAPEGQDLRD RPGRRPPARP APRSPPPRSP
       190        200        210        220        230        240
PPRSPPPSPP THRAHHVYPS LPTPLLRPSR RPSPRDCGTL PNRFVITPRR RYPIHQAQYS
       250        260        270        280        290        300
CLGVLPTVCW NGYHKKAVLS PRNSRMVCSP VTVRIAPPDR RFSRSAIPEQ IISSTLSSPS
       310        320        330        340        350        360
SNAPDPCAKE TVLSALKEKE KKRTVEEEDQ IFLDGQENKR RRHDSSGSGH SAFEPLVANG
       370        380        390        400        410        420
VPASFVPKPG SLKRGLNSQS SDDHLNKRSR SSSMSSLTGA YASGIPSSSR NAITSSYSST
       430        440        450        460        470        480
RGISQLWKRN GPSSSPFSSP ASSRSQTPER PAKKIREEEL CHHSSSSTPL AADRESQGEK
       490        500        510        520        530        540
AADTTPRKKQ NSNSQSTPGS SGQRKRKVQL LPSRRGEQLT LPPPPQLGYS ITAEDLDLEK
       550        560        570        580        590        600
KASLQWFNQA LEDKSDAASN SVTETPPITQ PSFTFTLPAA APASPPTSLL APSTNPLLES
       610        620        630        640        650        660
LKKMQTPPSL PPCPESAGAA TTEALSPPKT PSLLPPLGLS QSGPPGLLPS PSFDSKPPTT
       670        680        690        700        710        720
LLGLIPAPSM VPATDTKAPP TLQAETATKP QATSAPSPAP KQSFLFGTQN TSPSSPAAPA
       730        740        750        760        770        780
ASSAPPMFKP IFTAPPKSEK EGPTPPGPSV TATAPSSSSL PTTTSTTAPT FQPVFSSMGP
       790        800        810        820        830        840
PASVPLPAPF FKQTTTPATA PTTTAPLFTG LASATSAVAP ITSASPSTDS ASKPAFGFGI
       850        860        870        880        890        900
NSVSSSSVST TTSTATAASQ PFLFGAPQAS AASFTPAMGS IFQFGKPPAL PTTTTVTTFS
       910        920        930        940        950        960
QSLHTAVPTA TSSSAADFSG FGSTLATSAP ATSSQPTLTF SNTSTPTFNI PFGSSAKSPL
       970        980        990       1000       1010       1020
PSYPGANPQP AFGAAEGQPP GAAKPALAPS FGSSFTFGNS AAPAAAPTPA PPSMIKVVPA
      1030       1040       1050       1060       1070       1080
YVPTPIHPIF GGATHSAFGL KATASAFGAP ASSQPAFGGS TAVFFGAATS SGFGATTQTA
      1090       1100       1110       1120       1130       1140
SSGSSSSVFG STTPSPFTFG GSAAPAGSGS FGINVATPGS STTTGAFSFG AGQSGSTATS
      1150       1160       1170       1180       1190       1200
TPFAGGLGQN ALGTTGQSTP FAFNVSSTTE SKPVFGGTAT PTFGLNTPAP GVGTSGSSLS
      1210       1220       1230       1240
FGASSAPAQG FVGVAPFGSA ALSFSIGAGS KTPGARQRLQ ARRQHTRKK         10         20         30         40         50         60
MSPAAAAAGA GERRRPIASV RDGRGRGCGG PARAVLLGLS LVGLLLYLVP AAAALAWLTV
        70         80         90        100        110        120
GATAAWWGLS REPRGSRPLS SFVRKARHRR PLSSFVRKAR HRRTLFASPL AKSTANGNLL
       130        140        150        160        170        180
EPRTLLEGPD PAELLLMGSY LGKPGPPQPA AAPEGQDLRD RPGRRPPARP APRSPPPRSP
       190        200        210        220        230        240
PPRSPPPSPP THRAHHVYPS LPTPLLRPSR RPSPRDCGTL PNRFVITPRR RYPIHQAQYS
       250        260        270        280        290        300
CLGVLPTVCW NGYHKKAVLS PRNSRMVCSP VTVRIAPPDR RFSRSAIPEQ IISSTLSSPS
       310        320        330        340        350        360
SNAPDPCAKE TVLSALKEKE KKRTVEEEDQ IFLDGQENKR RRHDSSGSGH SAFEPLVANG
       370        380        390        400        410        420
VPASFVPKPG SLKRGLNSQS SDDHLNKRSR SSSMSSLTGA YASGIPSSSR NAITSSYSST
       430        440        450        460        470        480
RGISQLWKRN GPSSSPFSSP ASSRSQTPER PAKKIREEEL CHHSSSSTPL AADRESQGEK
       490        500        510        520        530        540
AADTTPRKKQ NSNSQSTPGS SGQRKRKVQL LPSRRGEQLT LPPPPQLGYS ITAEDLDLEK
       550        560        570        580        590        600
KASLQWFNQA LEDKSDAASN SVTETPPITQ PSFTFTLPAA APASPPTSLL APSTNPLLES
       610        620        630        640        650        660
LKKMQTPPSL PPCPESAGAA TTEALSPPKT PSLLPPLGLS QSGPPGLLPS PSFDSKPPTT
       670        680        690        700        710        720
LLGLIPAPSM VPATDTKAPP TLQAETATKP QATSAPSPAP KQSFLFGTQN TSPSSPAAPA
       730        740        750        760        770        780
ASSAPPMFKP IFTAPPKSEK EGPTPPGPSV TATAPSSSSL PTTTSTTAPT FQPVFSSMGP
       790        800        810        820        830        840
PASVPLPAPF FKQTTTPATA PTTTAPLFTG LASATSAVAP ITSASPSTDS ASKPAFGFGI
       850        860        870        880        890        900
NSVSSSSVST TTSTATAASQ PFLFGAPQAS AASFTPAMGS IFQFGKPPAL PTTTTVTTFS
       910        920        930        940        950        960
QSLHTAVPTA TSSSAADFSG FGSTLATSAP ATSSQPTLTF SNTSTPTFNI PFGSSAKSPL
       970        980        990       1000       1010       1020
PSYPGANPQP AFGAAEGQPP GAAKPALAPS FGSSFTFGNS AAPAAAPTPA PPSMIKVVPA
      1030       1040       1050       1060       1070       1080
YVPTPIHPIF GGATHSAFGL KATASAFGAP ASSQPAFGGS TAVFFGAATS SGFGATTQTA
      1090       1100       1110       1120       1130       1140
SSGSSSSVFG STTPSPFTFG GSAAPAGSGS FGINVATPGS STTTGAFSFG AGQSGSTATS
      1150       1160       1170       1180       1190       1200
TPFAGGLGQN ALGTTGQSTP FAFNVSSTTE SKPVFGGTAT PTFGLNTPAP GVGTSGSSLS
      1210       1220       1230       1240
FGASSAPAQG FVGVAPFGSA ALSFSIGAGS KTPGARQRLQ ARRQHTRKK

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q96HA1-1-unknown	MSPAAA...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q96HA1-266-unknown	MVCSPV...	266	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt83955
Q96HA1-266-unknown	MVCSPV...	266	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt83956
Q96HA1-377-unknown	NSQSSD...	377	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC14833
Q96HA1-377-unknown	NSQSSD...	377	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt143096
Q96HA1-377-unknown	NSQSSD...	377	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt143097

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...LKRGLN	376	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC14833
...LKRGLN	376	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt126314
...LKRGLN	376	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt126316
...HTRKK	1249	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...HTRKK	1249	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt79573

TopFIND

Q96HA1: Nuclear envelope pore membrane protein POM 121

General Information

3

N-termini

2

C-termini

1

Cleavages

0

Substrates

Sequence

Isoforms

Filter Information:

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

3 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates