Q03014: Hematopoietically-expressed homeobox protein HHEX

General Information

Protein names	- Hematopoietically-expressed homeobox protein HHEX - Homeobox protein HEX - Homeobox protein PRH
Gene names	HHEX
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q03014

3 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MQYPHPGPAA GAVGVPLYAP TPLLQPAHPT PFYIEDILGR GPAAPTPAPT LPSPNSSFTS
        70         80         90        100        110        120
LVSPYRTPVY EPTPIHPAFS HHSAAALAAA YGPGGFGGPL YPFPRTVNDY THALLRHDPL
       130        140        150        160        170        180
GKPLLWSPFL QRPLHKRKGG QVRFSNDQTI ELEKKFETQK YLSPPERKRL AKMLQLSERQ
       190        200        210        220        230        240
VKTWFQNRRA KWRRLKQENP QSNKKEELES LDSSCDQRQD LPSEQNKGAS LDSSQCSPSP
       250        260        270
ASQEDLESEI SEDSDQEVDI EGDKSYFNAG

Isoforms

Sequence View

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Physiological Relevance:

Evidence Codes:

Methodology:

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Biological System:

Protease Assignment Confidence:

Evidence Names:

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Protein Neighborhood

Domains & Features

3 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q03014-1-unknown	MQYPHP...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q03014-173-unknown	MLQLSE...	173	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000450017
Q03014-173-unknown	MLQLSE...	173	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000447953
Q03014-209-unknown	ESLDSS...	209	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC14368

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...KKEELE	208	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC14368
	...YFNAG	270	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAM_HUMAN	208	EELE.\|.ESLD	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)