Q86WR7: Proline and serine-rich protein 2

General Information

Protein names	- Proline and serine-rich protein 2
Gene names	PROSER2
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q86WR7

2 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MPVTHRKSDA SDMNSDTSPS CRLRAFSRGG SLESRSSSSR SRSFTLDDES LKYLTHEEKD
        70         80         90        100        110        120
VLLFFEETID SLDEDFEEPV LCDGGVCCLC SPSLEESTSS PSEPEDVIDL VQPAPGAGEA
       130        140        150        160        170        180
EGLPEGTQAA GPAPAGKEHR KQDAETPPPP DPPAPETLLA PPPLPSTPDP PRRELRAPSP
       190        200        210        220        230        240
PVEHPRLLRS VPTPLVMAQK ISERMAGNEA LSPTSPFREG RPGEWRTPAA RGPRSGDPGP
       250        260        270        280        290        300
GPSHPAQPKA PRFPSNIIVT NGAAREPRRT LSRAAVSVQE RRAQVLATIH GHAGAFPAAG
       310        320        330        340        350        360
DAGEGAPGGG SSPERVARGR GLPGPAESLR AGGQAPRGPA LANGFPSAHE ALKSAPSSFA
       370        380        390        400        410        420
PAGKSLCFRP GPALPSTRAR QSFPGPRQPN GAQDWRRADS LPRPQGITVQ FAGRGSSEEA
       430
RREALRKLGL LRESS

Isoforms

- Isoform 2 of Proline and serine-rich protein 2

Sequence View

Protein Neighborhood

Domains & Features

2 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q86WR7-1-unknown	MPVTHR...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q86WR7-1-unknown	MPVTHR...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt86322
Q86WR7-196-unknown	VMAQKI...	196	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC14696
Q86WR7-196-unknown	VMAQKI...	196	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt146466

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...VPTPLV	195	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC14696
...VPTPLV	195	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt129773
...LRESS	435	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...LRESS	435	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt81940

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAM_HUMAN	195	TPLV.\|.VMAQ	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

TopFIND

Q86WR7: Proline and serine-rich protein 2

General Information

2

N-termini

2

C-termini

1

Cleavages

0

Substrates

Sequence

Isoforms

Filter Information:

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

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Protein Neighborhood

Domains & Features

2 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates