O75528: Transcriptional adapter 3

General Information

Protein names	- Transcriptional adapter 3 - ADA3 homolog - hADA3 - STAF54 - Transcriptional adapter 3-like - ADA3-like protein
Gene names	TADA3
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	O75528

3 N-termini

3 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MSELKDCPLQ FHDFKSVDHL KVCPRYTAVL ARSEDDGIGI EELDTLQLEL ETLLSSASRR
        70         80         90        100        110        120
LRVLEAETQI LTDWQDKKGD RRFLKLGRDH ELGAPPKHGK PKKQKLEGKA GHGPGPGPGR
       130        140        150        160        170        180
PKSKNLQPKI QEYEFTDDPI DVPRIPKNDA PNRFWASVEP YCADITSEEV RTLEELLKPP
       190        200        210        220        230        240
EDEAEHYKIP PLGKHYSQRW AQEDLLEEQK DGARAAAVAD KKKGLMGPLT ELDTKDVDAL
       250        260        270        280        290        300
LKKSEAQHEQ PEDGCPFGAL TQRLLQALVE ENIISPMEDS PIPDMSGKES GADGASTSPR
       310        320        330        340        350        360
NQNKPFSVPH TKSLESRIKE ELIAQGLLES EDRPAEDSED EVLAELRKRQ AELKALSAHN
       370        380        390        400        410        420
RTKKHDLLRL AKEEVSRQEL RQRVRMADNE VMDAFRKIMA ARQKKRTPTK KEKDQAWKTL
       430
KERESILKLL DG

Isoforms

- Isoform 2 of Transcriptional adapter 3

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

3 N-termini - 3 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name	Publications (PMID)
O75528-1-unknown	MSELKD...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
O75528-1-unknown	MSELKD...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt91436
O75528-162-unknown	CADITS...	162		unknown		Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
O75528-162-unknown	CADITS...	162	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt160348
O75528-226-unknown	MGPLTE...	226	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC13843
O75528-226-unknown	MGPLTE...	226	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt147571

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
...KKKGLM	225	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC13843
...KKKGLM	225	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt130923
...HDLLRL	369	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt87054
...KLLDG	432	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
...KLLDG	432		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAM_HUMAN	225	KGLM.\|.MGPL	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)