Q8WUQ7: Cactin
Protein names | - Cactin - Renal carcinoma antigen NY-REN-24 |
---|---|
Gene names | CACTIN |
Organism | Homo sapiens |
Protease Family | |
Protease ID | |
Chromosome location | |
UniProt ID | Q8WUQ7 |
2
N-termini
2
C-termini
1
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MGRDTRSRSR SAGRRGRRRQ SQSGSRSRSR SHGRRNRRRR EDEGRRRRRR RSRERRSDSE
70 80 90 100 110 120
EERWQRSGMR SRSPPRPKWH SRDGSSQSDS GEEQSRGQWA RRRRRARSWS PSSSASSSAS
130 140 150 160 170 180
PGRSQSPRAA AAALSQQQSL QERLRLREER KQQEELMKAF ETPEEKRARR LAKKEAKERK
190 200 210 220 230 240
KREKMGWGEE YMGYTNTDNP FGDNNLLGTF IWNKALEKKG ISHLEEKELK ERNKRIQEDN
250 260 270 280 290 300
RLELQKVKQL RLEREREKAM REQELEMLQR EKEAEHFKTW EEQEDNFHLQ QAKLRSKIRI
310 320 330 340 350 360
RDGRAKPIDL LAKYISAEDD DLAVEMHEPY TFLNGLTVAD MEDLLEDIQV YMELEQGKNA
370 380 390 400 410 420
DFWRDMTTIT EDEISKLRKL EASGKGPGER REGVNASVSS DVQSVFKGKT YNQLQVIFQG
430 440 450 460 470 480
IEGKIRAGGP NLDMGYWESL LQQLRAHMAR ARLRERHQDV LRQKLYKLKQ EQGVESEPLF
490 500 510 520 530 540
PILKQEPQSP SRSLEPEDAA PTPPGPSSEG GPAEAEVDGA TPTEGDGDGD GEGEGEGEAV
550 560 570 580 590 600
LMEEDLIQQS LDDYDAGRYS PRLLTAHELP LDAHVLEPDE DLQRLQLSRQ QLQVTGDASE
610 620 630 640 650 660
SAEDIFFRRA KEGMGQDEAQ FSVEMPLTGK AYLWADKYRP RKPRFFNRVH TGFEWNKYNQ
670 680 690 700 710 720
THYDFDNPPP KIVQGYKFNI FYPDLIDKRS TPEYFLEACA DNKDFAILRF HAGPPYEDIA
730 740 750
FKIVNREWEY SHRHGFRCQF ANGIFQLWFH FKRYRYRR
Isoforms
- Isoform 2 of CactinSequence View
10 20 30 40 50 60
MGRDTRSRSR SAGRRGRRRQ SQSGSRSRSR SHGRRNRRRR EDEGRRRRRR RSRERRSDSE
70 80 90 100 110 120
EERWQRSGMR SRSPPRPKWH SRDGSSQSDS GEEQSRGQWA RRRRRARSWS PSSSASSSAS
130 140 150 160 170 180
PGRSQSPRAA AAALSQQQSL QERLRLREER KQQEELMKAF ETPEEKRARR LAKKEAKERK
190 200 210 220 230 240
KREKMGWGEE YMGYTNTDNP FGDNNLLGTF IWNKALEKKG ISHLEEKELK ERNKRIQEDN
250 260 270 280 290 300
RLELQKVKQL RLEREREKAM REQELEMLQR EKEAEHFKTW EEQEDNFHLQ QAKLRSKIRI
310 320 330 340 350 360
RDGRAKPIDL LAKYISAEDD DLAVEMHEPY TFLNGLTVAD MEDLLEDIQV YMELEQGKNA
370 380 390 400 410 420
DFWRDMTTIT EDEISKLRKL EASGKGPGER REGVNASVSS DVQSVFKGKT YNQLQVIFQG
430 440 450 460 470 480
IEGKIRAGGP NLDMGYWESL LQQLRAHMAR ARLRERHQDV LRQKLYKLKQ EQGVESEPLF
490 500 510 520 530 540
PILKQEPQSP SRSLEPEDAA PTPPGPSSEG GPAEAEVDGA TPTEGDGDGD GEGEGEGEAV
550 560 570 580 590 600
LMEEDLIQQS LDDYDAGRYS PRLLTAHELP LDAHVLEPDE DLQRLQLSRQ QLQVTGDASE
610 620 630 640 650 660
SAEDIFFRRA KEGMGQDEAQ FSVEMPLTGK AYLWADKYRP RKPRFFNRVH TGFEWNKYNQ
670 680 690 700 710 720
THYDFDNPPP KIVQGYKFNI FYPDLIDKRS TPEYFLEACA DNKDFAILRF HAGPPYEDIA
730 740 750
FKIVNREWEY SHRHGFRCQF ANGIFQLWFH FKRYRYRR
Protein Neighborhood
Domains & Features
2 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
Q8WUQ7-1-unknown | MGRDTR... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
Q8WUQ7-1-unknown | MGRDTR... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt69380 | |||
Q8WUQ7-157-unknown | MKAFET... | 157 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC14789 | |||
Q8WUQ7-157-unknown | MKAFET... | 157 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt145053 |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...QQEELM | 156 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC14789 | |||
...QQEELM | 156 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt128332 | |||
...YRYRR | 758 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
...YRYRR | 758 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt93361 |
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
GRAM_HUMAN | 156 | EELM.|.MKAF | inferred from experiment | unknown | MEROPS | Bovenschen N | de Poot SA et al.:Human and mouse granzyme M disp... (S01.139) | 21564021, |
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
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