Q14493: Histone RNA hairpin-binding protein

General Information

Protein names	- Histone RNA hairpin-binding protein - Histone stem-loop-binding protein
Gene names	SLBP
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q14493

3 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MACRPRSPPR HQSRCDGDAS PPSPARWSLG RKRRADGRRW RPEDAEEAEH RGAERRPESF
        70         80         90        100        110        120
TTPEGPKPRS RCSDWASAVE EDEMRTRVNK EMARYKRKLL INDFGRERKS SSGSSDSKES
       130        140        150        160        170        180
MSTVPADFET DESVLMRRQK QINYGKNTIA YDRYIKEVPR HLRQPGIHPK TPNKFKKYSR
       190        200        210        220        230        240
RSWDQQIKLW KVALHFWDPP AEEGCDLQEI HPVDLESAES SSEPQTSSQD DFDVYSGTPT
       250        260        270
KVRHMDSQVE DEFDLEACLT EPLRDFSAMS

Isoforms

- Isoform 2 of Histone RNA hairpin-binding protein

Sequence View

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Protein Neighborhood

Domains & Features

3 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q14493-1-unknown	MACRPR...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q14493-17-	GDASPP...	17		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q14493-17-	GDASPP...	17		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q14493-122-unknown	STVPAD...	122	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC14488
Q14493-122-unknown	STVPAD...	122	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt141481

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...SKESMS	121	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC14488
...SKESMS	121	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt124655
...FSAMS	270	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...FSAMS	270	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt85548

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAM_HUMAN	121	ESMS.\|.STVP	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)