P46783: 40S ribosomal protein S10

General Information

Protein names	- 40S ribosomal protein S10 - Small ribosomal subunit protein eS10 {ECO:0000303\|PubMed:24524803}
Gene names	RPS10
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P46783

11 N-termini

5 C-termini

4 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MLMPKKNRIA IYELLFKEGV MVAKKDVHMP KHPELADKNV PNLHVMKAMQ SLKSRGYVKE
        70         80         90        100        110        120
QFAWRHFYWY LTNEGIQYLR DYLHLPPEIV PATLRRSRPE TGRPRPKGLE GERPARLTRG
       130        140        150        160
EADRDTYRRS AVPPGADKKA EAGAGSATEF QFRGGFGRGR GQPPQ

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

11 N-termini - 5 C-termini - 4 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P46783-1-	MLMPKK...	1		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
P46783-1-	MLMPKK...	1		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P46783-1-	MLMPKK...	1		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
P46783-1-unknown	MLMPKK...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P46783-1-unknown	MLMPKK...	1		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
P46783-1-unknown	MLMPKK...	1		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
P46783-37-unknown	DKNVPN...	37	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC19123
P46783-47-unknown	KAMQSL...	47	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC14137
P46783-106-	PKGLEG...	106		Subtiligase Based Positive Selection		Wells	apoptotic_RPMI_Dox	23264352
P46783-130-	SAVPPG...	130		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_Etoposide	23264352
P46783-130-	SAVPPG...	130		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
P46783-130-unknown	SAVPPG...	130		unknown			Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
P46783-139-	KAEAGA...	139		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
P46783-139-unknown	KAEAGA...	139		unknown			Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
P46783-142-unknown	AGAGSA...	142	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC19124
P46783-143-unknown	GAGSAT...	143	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC14138

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...HPELAD	36	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC19123
...NLHVMK	46	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC14137
...DKKAEA	141	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC19124
...KKAEAG	142	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC14138
...GQPPQ	165	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MEP1B_HUMAN	36	ELAD.\|.DKNV	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
GRAM_HUMAN	46	HVMK.\|.KAMQ	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,
MEP1B_HUMAN	141	KAEA.\|.AGAG	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
GRAM_HUMAN	142	AEAG.\|.GAGS	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)