Q13416: Origin recognition complex subunit 2

General Information

Protein names	- Origin recognition complex subunit 2
Gene names	ORC2
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q13416

2 N-termini

4 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MSKPELKEDK MLEVHFVGDD DVLNHILDRE GGAKLKKERA QLLVNPKKII KKPEYDLEED
        70         80         90        100        110        120
DQEVLKDQNY VEIMGRDVQE SLKNGSATGG GNKVYSFQNR KHSEKMAKLA SELAKTPQKS
       130        140        150        160        170        180
VSFSLKNDPE ITINVPQSSK GHSASDKVQP KNNDKSEFLS TAPRSLRKRL IVPRSHSDSE
       190        200        210        220        230        240
SEYSASNSED DEGVAQEHEE DTNAVIFSQK IQAQNRVVSA PVGKETPSKR MKRDKTSDLV
       250        260        270        280        290        300
EEYFEAHSSS KVLTSDRTLQ KLKRAKLDQQ TLRNLLSKVS PSFSAELKQL NQQYEKLFHK
       310        320        330        340        350        360
WMLQLHLGFN IVLYGLGSKR DLLERFRTTM LQDSIHVVIN GFFPGISVKS VLNSITEEVL
       370        380        390        400        410        420
DHMGTFRSIL DQLDWIVNKF KEDSSLELFL LIHNLDSQML RGEKSQQIIG QLSSLHNIYL
       430        440        450        460        470        480
IASIDHLNAP LMWDHAKQSL FNWLWYETTT YSPYTEETSY ENSLLVKQSG SLPLSSLTHV
       490        500        510        520        530        540
LRSLTPNARG IFRLLIKYQL DNQDNPSYIG LSFQDFYQQC REAFLVNSDL TLRAQLTEFR
       550        560        570
DHKLIRTKKG TDGVEYLLIP VDNGTLTDFL EKEEEEA

Isoforms

Sequence View

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Evidence Names:

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Protein Neighborhood

Domains & Features

2 N-termini - 4 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q13416-1-unknown	MSKPEL...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q13416-83-unknown	KNGSAT...	83		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC14415

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...QNYVEI	72	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000396641
...VQESLK	82	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC14415
...KMAKLA	109	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000386390
...EEEEA	577	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAM_HUMAN	82	ESLK.\|.KNGS	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)