O75494: Serine/arginine-rich splicing factor 10
Protein names | - Serine/arginine-rich splicing factor 10 - 40 kDa SR-repressor protein - SRrp40 - FUS-interacting serine-arginine-rich protein 1 - Splicing factor SRp38 - Splicing factor, arginine/serine-rich 13A - TLS-associated protein with Ser-Arg repeats - TASR - TLS-associated protein with SR repeats - TLS-associated serine-arginine protein - TLS-associated SR protein |
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Gene names | SRSF10 |
Organism | Homo sapiens |
Protease Family | |
Protease ID | |
Chromosome location | |
UniProt ID | O75494 |
3
N-termini
3
C-termini
2
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MSRYLRPPNT SLFVRNVADD TRSEDLRREF GRYGPIVDVY VPLDFYTRRP RGFAYVQFED
70 80 90 100 110 120
VRDAEDALHN LDRKWICGRQ IEIQFAQGDR KTPNQMKAKE GRNVYSSSRY DDYDRYRRSR
130 140 150 160 170 180
SRSYERRRSR SRSFDYNYRR SYSPRNSRPT GRPRRSRSHS DNDRFKHRNR SFSRSKSNSR
190 200 210 220 230 240
SRSKSQPKKE MKAKSRSRSA SHTKTRGTSK TDSKTHYKSG SRYEKESRKK EPPRSKSQSR
250 260
SQSRSRSKSR SRSWTSPKSS GH
Isoforms
- Isoform 2 of Serine/arginine-rich splicing factor 10 - Isoform 3 of Serine/arginine-rich splicing factor 10 - Isoform 4 of Serine/arginine-rich splicing factor 10 - Isoform 5 of Serine/arginine-rich splicing factor 10 - Isoform 6 of Serine/arginine-rich splicing factor 10Sequence View
10 20 30 40 50 60
MSRYLRPPNT SLFVRNVADD TRSEDLRREF GRYGPIVDVY VPLDFYTRRP RGFAYVQFED
70 80 90 100 110 120
VRDAEDALHN LDRKWICGRQ IEIQFAQGDR KTPNQMKAKE GRNVYSSSRY DDYDRYRRSR
130 140 150 160 170 180
SRSYERRRSR SRSFDYNYRR SYSPRNSRPT GRPRRSRSHS DNDRFKHRNR SFSRSKSNSR
190 200 210 220 230 240
SRSKSQPKKE MKAKSRSRSA SHTKTRGTSK TDSKTHYKSG SRYEKESRKK EPPRSKSQSR
250 260
SQSRSRSKSR SRSWTSPKSS GH
10 20 30 40 50 60
MSRYLRPPNT SLFVRNVADD TRSEDLRREF GRYGPIVDVY VPLDFYTRRP RGFAYVQFED
70 80 90 100 110 120
VRDAEDALHN LDRKWICGRQ IEIQFAQGDR KTPNQMKAKE GRNVYSSSRY DDYDRYRRSR
130 140 150 160 170 180
SRSYERRRSR SRSFDYNYRR SYSPRNSRPT GRPRRSRSHS DNDRFKHRNR SFSRSKSNSR
190 200 210 220 230 240
SRSKSQPKKE MKAKSRSRSA SHTKTRGTSK TDSKTHYKSG SRYEKESRKK EPPRSKSQSR
250 260
SQSRSRSKSR SRSWTSPKSS GH
10 20 30 40 50 60
MSRYLRPPNT SLFVRNVADD TRSEDLRREF GRYGPIVDVY VPLDFYTRRP RGFAYVQFED
70 80 90 100 110 120
VRDAEDALHN LDRKWICGRQ IEIQFAQGDR KTPNQMKAKE GRNVYSSSRY DDYDRYRRSR
130 140 150 160 170 180
SRSYERRRSR SRSFDYNYRR SYSPRNSRPT GRPRRSRSHS DNDRFKHRNR SFSRSKSNSR
190 200 210 220 230 240
SRSKSQPKKE MKAKSRSRSA SHTKTRGTSK TDSKTHYKSG SRYEKESRKK EPPRSKSQSR
250 260
SQSRSRSKSR SRSWTSPKSS GH
10 20 30 40 50 60
MSRYLRPPNT SLFVRNVADD TRSEDLRREF GRYGPIVDVY VPLDFYTRRP RGFAYVQFED
70 80 90 100 110 120
VRDAEDALHN LDRKWICGRQ IEIQFAQGDR KTPNQMKAKE GRNVYSSSRY DDYDRYRRSR
130 140 150 160 170 180
SRSYERRRSR SRSFDYNYRR SYSPRNSRPT GRPRRSRSHS DNDRFKHRNR SFSRSKSNSR
190 200 210 220 230 240
SRSKSQPKKE MKAKSRSRSA SHTKTRGTSK TDSKTHYKSG SRYEKESRKK EPPRSKSQSR
250 260
SQSRSRSKSR SRSWTSPKSS GH
10 20 30 40 50 60
MSRYLRPPNT SLFVRNVADD TRSEDLRREF GRYGPIVDVY VPLDFYTRRP RGFAYVQFED
70 80 90 100 110 120
VRDAEDALHN LDRKWICGRQ IEIQFAQGDR KTPNQMKAKE GRNVYSSSRY DDYDRYRRSR
130 140 150 160 170 180
SRSYERRRSR SRSFDYNYRR SYSPRNSRPT GRPRRSRSHS DNDRFKHRNR SFSRSKSNSR
190 200 210 220 230 240
SRSKSQPKKE MKAKSRSRSA SHTKTRGTSK TDSKTHYKSG SRYEKESRKK EPPRSKSQSR
250 260
SQSRSRSKSR SRSWTSPKSS GH
Protein Neighborhood
Domains & Features
3 N-termini - 3 C-termini - 2 Cleavages - 0 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
O75494-1-unknown | MSRYLR... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
O75494-1-unknown | MSRYLR... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt90721 | |||
O75494-1-unknown | MSRYLR... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt90722 | |||
O75494-1-unknown | MSRYLR... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt90723 | |||
O75494-1-unknown | MSRYLR... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt90724 | |||
O75494-1-unknown | MSRYLR... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt90725 | |||
O75494-55-unknown | YVQFED... | 55 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC5255 | |||
O75494-55-unknown | YVQFED... | 55 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt139536 | |||
O75494-55-unknown | YVQFED... | 55 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt139537 | |||
O75494-55-unknown | YVQFED... | 55 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt139538 | |||
O75494-55-unknown | YVQFED... | 55 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt139539 | |||
O75494-55-unknown | YVQFED... | 55 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt139541 | |||
O75494-95-unknown | QMKAKE... | 95 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC13837 | |||
O75494-95-unknown | QMKAKE... | 95 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt142105 | |||
O75494-95-unknown | QMKAKE... | 95 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt142106 | |||
O75494-95-unknown | QMKAKE... | 95 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt142107 | |||
O75494-95-unknown | QMKAKE... | 95 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt142108 | |||
O75494-95-unknown | QMKAKE... | 95 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt142111 |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...PRGFAY | 54 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC5255 | |||
...PRGFAY | 54 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt122626 | |||
...PRGFAY | 54 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt122627 | |||
...PRGFAY | 54 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt122628 | |||
...PRGFAY | 54 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt122629 | |||
...PRGFAY | 54 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt122631 | |||
...RKTPNQ | 94 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC13837 | |||
...RKTPNQ | 94 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt125290 | |||
...RKTPNQ | 94 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt125291 | |||
...RKTPNQ | 94 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt125292 | |||
...RKTPNQ | 94 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt125293 | |||
...RKTPNQ | 94 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt125295 | |||
...KSSGH | 262 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
...KSSGH | 262 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt86339 |
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
CATL1_HUMAN | 54 | GFAY.|.YVQF | inferred from experiment | unknown | MEROPS | Schilling O | Biniossek ML et al.:Proteomic identification of pro... (C01.060) | 21967108, |
GRAM_HUMAN | 94 | TPNQ.|.QMKA | inferred from experiment | unknown | MEROPS | Bovenschen N | de Poot SA et al.:Human and mouse granzyme M disp... (S01.139) | 21564021, |
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
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